Conivaptan

DRUG13 trials

Sponsors

Cumberland Pharmaceuticals, Columbia University, Northwestern University, Albert Einstein Healthcare Network, Hennepin County Medical Center, Minneapolis

Conditions

Acute Cerebrovascular AccidentAcute Decompensated Heart FailureCerebral EdemaCerebral HemorrhageChronic Heart FailureEuvolemiaHeart FailureHypervolemia

Phase 1

Conivaptan for the Reduction of Cerebral Edema in Intracerebral Hemorrhage- A Safety and Tolerability Study

CompletedNCT03000283

Jesse CorryCerebral Edema, Cerebral Hemorrhage, Intracerebral Hemorrhage +1

Start: 2017-03-22End: 2019-04-15Updated: 2020-04-17

Phase 2

Safety and Efficacy Study of YM087 (Conivaptan) in Patients With Acute Decompensated Heart Failure

CompletedNCT00057356

Cumberland PharmaceuticalsChronic Heart Failure

Start: 2002-11-30End: 2004-03-31Updated: 2014-05-02

A Study to Assess the Safety and Effects of Intravenous (IV) Conivaptan on the Hepatic Hemodynamic Response in Cirrhotic Patients

CompletedNCT00592475

Cumberland PharmaceuticalsLiver Cirrhosis

Start: 2007-12-31End: 2008-11-30Updated: 2014-05-15

Study of Stroke Related Edema Treatments

WithdrawnNCT01954290

University of FloridaAcute Cerebrovascular Accident, Cerebral Edema

Start: 2015-09-30End: 2015-09-30Updated: 2016-12-14

Phase 3

An Open-Label Study of YM087 (Conivaptan) in Patients With Euvolemic or Hypervolemic Hyponatremia

CompletedNCT00379847

Cumberland PharmaceuticalsHyponatremia

Start: 2004-02-29End: 2005-06-30Updated: 2014-05-02

Study of Efficacy & Safety for 3 Infusion Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia

CompletedNCT00478192

Cumberland PharmaceuticalsHyponatremia

Start: 2007-04-30End: 2008-08-31Updated: 2014-05-15

Safety and Efficacy of Conivaptan for the Correction of Hyponatremia in Neurological Patients

WithdrawnNCT00684164

Columbia UniversityHyponatremia

Start: 2008-05-31End: 2010-06-30Updated: 2015-03-06

Safety and Efficacy of Conivaptan in Hyponatremic Patients With Symptomatic Acute Decompensated Heart Failure (ADHF)

TerminatedNCT00843986

Cumberland PharmaceuticalsAcute Decompensated Heart Failure, Hyponatremia

Start: 2009-04-30End: 2009-08-31Updated: 2014-05-15

Phase 4

A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia

CompletedNCT00435591

Cumberland PharmaceuticalsEuvolemia, Hypervolemia, Hyponatremia

Start: 2007-01-31End: 2008-09-30Updated: 2014-05-15

Use of Conivaptan (Vaprisol) for Hyponatremic Neuro-ICU Patients

TerminatedNCT00727090

Northwestern UniversityHyponatremia

Start: 2008-08-31End: 2010-02-28Updated: 2022-03-28

Diuretic and Renal Effects of Vaprisol When Administered Along With Furosemide and Nesiritide Continuous Infusion

WithdrawnNCT00806910

Albert Einstein Healthcare NetworkHeart Failure

Start: 2008-10-31End: 2010-02-28Updated: 2011-06-23

Effects on Exercise Hemodynamics of Vasopressin Blockade by Conivaptan Infusion in Heart Failure Patients

CompletedNCT01752543

Finn GustafssonHeart Failure

Start: 2013-12-31End: 2015-06-30Updated: 2015-06-17

Unknown Phase

Comparing the Effects of Conivaptan and Diuretics on Plasma Neurohormones and Renal Blood Flow in Patients With Chronic Congestive Heart Failure

Hennepin County Medical Center, MinneapolisHeart Failure

Start: 2009-07-31End: 2010-03-31Target: 8Updated: 2009-06-18

Related Papers

Conivaptan for the Reduction of Cerebral Edema in Intracerebral Hemorrhage: A Safety and Tolerability Study.

2020-05-0113 citations

Use of Conivaptan (Vaprisol) for hyponatremic neuro-ICU patients.

2010-08-0125 citations