Cholestyramine

DRUG20 trials

Sponsors

Tamura Shigeki, National Heart, Lung, and Blood Institute (NHLBI), Shiraz University of Medical Sciences, Louisville Metabolic and Atherosclerosis Research Center, Sanofi

Conditions

Acute Graft Versus Host DiseaseAdvanced Pancreatic AdenocarcinomaCardiovascular DiseasesCoronary DiseaseDIABETESDIABETIC NEUROPATHYDIABETIC RETINOPATHYGastric post-ESD ulcers Gastric post-ESD ulcers

Phase 1

Pharmacokinetic and Tolerability Study of 14 mg Single Dose of Teriflunomide in Subjects With Severe Renal Impairment

CompletedNCT01239459

SanofiRenal Impairment

Start: 2010-11-30End: 2011-03-31Updated: 2012-03-01

A Study to Evaluate the Pharmacokinetic Profiles of Single 14 mg Teriflunomide Tablet in Healthy Chinese Volunteers

CompletedNCT02046629

SanofiMultiple Sclerosis

Start: 2014-05-31End: 2014-07-31Updated: 2014-08-21

Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

RecruitingNCT05443425

City of Hope Medical CenterAcute Graft Versus Host Disease, Hematopoietic and Lymphoid System Neoplasm

Start: 2023-06-16End: 2027-01-05Target: 18Updated: 2025-07-04

A Study to Evaluate the Effect of Cholestyramine on LOXO-783 in Healthy Participants

CompletedNCT05894928

Eli Lilly and CompanyHealthy

Start: 2023-06-07End: 2023-07-09Updated: 2023-09-26

Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer

RecruitingNCT06454383

City of Hope Medical CenterAdvanced Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8 +1

Start: 2024-05-13End: 2026-11-13Target: 19Updated: 2025-04-10

Phase 2

Harvard Atherosclerosis Reversibility Project (HARP)

CompletedNCT00000461

National Heart, Lung, and Blood Institute (NHLBI)Cardiovascular Diseases, Coronary Disease, Heart Diseases +1

Start: 1986-12-31End: 1992-11-30Updated: 2016-03-16

An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

CompletedNCT02890992

SanofiHypercholesterolaemia

Start: 2016-09-15End: 2019-02-22Updated: 2019-09-06

Effect of cholestyramine on post-ESD ulcer healing

RecruitingJPRN-jRCTs031200235

Tamura ShigekiGastric post-ESD ulcers Gastric post-ESD ulcers

Start: 2021-03-08Target: 100Updated: 2025-07-18

Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma in African-American and European-American Patients

Active, not recruitingNCT05014646

City of Hope Medical CenterSmoldering Plasma Cell Myeloma

Start: 2022-03-07End: 2027-01-16Updated: 2026-03-05

Phase 3

Lipid Research Clinics Coronary Primary Prevention Trial (CPPT)

CompletedNCT00000488

National Heart, Lung, and Blood Institute (NHLBI)Cardiovascular Diseases, Coronary Disease, Heart Diseases +1

Start: 1973-06-30End: 1989-10-31Updated: 2016-04-14

Post Coronary Artery Bypass Graft (CABG) Study

CompletedNCT00000463

National Heart, Lung, and Blood Institute (NHLBI)Cardiovascular Diseases, Coronary Disease, Heart Diseases +1

Start: 1987-04-30End: 1998-12-31Updated: 2016-04-14

NHLBI Type II Coronary Intervention Study

CompletedNCT00000594

National Heart, Lung, and Blood Institute (NHLBI)Cardiovascular Diseases, Coronary Disease, Heart Diseases +3

Start: 1971-11-30End: 1976-11-30Updated: 2012-04-27

Effect of Teriflunomide on Immune Cell Subsets in the Blood of Patients With Multiple Sclerosis

CompletedNCT01863888

SanofiMultiple Sclerosis

Start: 2013-10-31End: 2015-01-31Updated: 2015-03-13

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia

CompletedNCT03510715

SanofiHypercholesterolemia

Start: 2018-08-31End: 2020-02-17Updated: 2020-12-29

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

CompletedNCT03510884

SanofiHypercholesterolaemia

Start: 2018-05-31End: 2022-08-05Updated: 2023-05-06

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

RecruitingNCT06141473

SanofiMultiple Sclerosis

Start: 2023-12-13End: 2027-05-06Target: 1600Updated: 2026-03-05

Phase 4

A Single Research Site Bile Acid Sequestrant Acceptability (BASA) Scale Pilot Validation Study

CompletedNCT01062269

Louisville Metabolic and Atherosclerosis Research CenterHealthy

Start: 2010-01-31End: 2010-04-30Updated: 2011-07-12

Comparison of Colesevelam Hydrogen Chloride (HCl) Powder For Oral Suspension Versus Generic Cholestyramine Through Use of the Bile Acid Sequestrant Acceptability (BASA) Scale

CompletedNCT01122108

Louisville Metabolic and Atherosclerosis Research CenterHealthy

Start: 2010-04-30End: 2010-06-30Updated: 2010-10-07

PRELIMINARY EVALUATION OF PHARMACOLOGICAL LOWERING OF AGEs

CompletedNCT02249897

University of ChileDIABETES, DIABETIC NEUROPATHY, DIABETIC RETINOPATHY

Start: 2015-01-31End: 2017-12-31Updated: 2018-02-14

Unknown Phase

Low Doses of Cholestyramine in the Treatment of Hyperthyroidism

CompletedNCT00677469

Shiraz University of Medical SciencesGraves Disease

Start: 2007-07-31End: 2008-01-31Updated: 2008-05-14

Related Papers

Alirocumab in Pediatric Patients With Heterozygous Familial Hypercholesterolemia

JAMA Pediatrics2024-02-0524 citations

Efficacy and Safety of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia: Phase 3, Multinational Open-Label Study

Arteriosclerosis Thrombosis and Vascular Biology2022-11-0337 citations

PCSK9 inhibition with alirocumab in pediatric patients with heterozygous familial hypercholesterolemia: The ODYSSEY KIDS study.

2020-03-2836 citations

Teri-DYNAMIC: Exploring the impact of teriflunomide on immune cell population size, receptor repertoire, and function in patients with RRMS

2017-01-012 citations

TERI-DYNAMIC: Exploring the Impact of Teriflunomide on Immune Cell Population Size, Receptor Repertoire, and Function in Patients With RRMS (P5.282)

Neurology2016-04-055 citations