Certolizumab

DRUG12 trials

Sponsors

University of Rochester, Baylor College of Medicine, Memorial Sloan Kettering Cancer Center, Jagiellonian University, Brigham and Women's Hospital

Conditions

Ankylosing SpondylitisArthritis, RheumatoidAtopic DermatitisCardiovascular DiseaseChronic Nonbacterial OsteomyelitisChronic Recurrent Multifocal OsteomyelitisCrohns DiseaseEnthesitis

Phase 1

Certolizumab in Combination With Chemotherapy for Patients With Stage IV Lung Adenocarcinomas

CompletedNCT02120807

Memorial Sloan Kettering Cancer CenterStage IV Lung Adenocarcinoma

Start: 2014-04-15End: 2023-01-24Updated: 2023-01-26

Phase 2

Adding Certolizumab to Chemotherapy + Nivolumab in People Who Have Lung Cancer That Can Be Treated With Surgery

RecruitingNCT04991025

Memorial Sloan Kettering Cancer CenterLung Cancer, Lung Cancer Stage II, Lung Cancer Stage III

Start: 2022-10-19End: 2026-10-31Target: 60Updated: 2025-10-17

A Study to Evaluate the Nipocalimab and Certolizumab Combination Therapy in Participants With Active Rheumatoid Arthritis

CompletedNCT06028438

Janssen Research & Development, LLCArthritis, Rheumatoid

Start: 2023-08-15End: 2024-10-29Updated: 2025-10-16

Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty

Not yet recruitingNCT07138898

NYU Langone HealthRheumatic Disease

Start: 2025-09-30End: 2027-09-30Target: 80Updated: 2025-08-24

Phase 3

Treatment of Rheumatoid Arthritis With DMARDs: Predictors of Response

RecruitingNCT03414502

University of NebraskaRheumatoid Arthritis

Start: 2007-12-10End: 2029-03-31Target: 400Updated: 2025-08-08

Phase 4

Effects of Biological Treatment on Blood Pressure and Endothelial Function in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

Jagiellonian UniversityAnkylosing Spondylitis, Hypertension, Psoriatic Arthritis +1

Start: 2013-06-30Target: 100Updated: 2014-05-07

Utilization of a Microdevice for Psoriasis and Atopic Dermatitis

Not yet recruitingNCT07352566

University of California, San FranciscoAtopic Dermatitis, Psoriasis

Start: 2026-01-01End: 2030-06-01Target: 10Updated: 2026-01-20

Unknown Phase

Certolizumab and Lower Extremity Lymph Flow in Rheumatoid Arthritis (RA)

CompletedNCT01098201

University of RochesterRheumatoid Arthritis

Start: 2010-10-31End: 2014-07-31Updated: 2015-09-21

EUS Evaluation of Perianal and Peri-rectal Fistulizing Crohn's Disease With CERTOLIZUMAB Treatment

TerminatedNCT01582568

Baylor College of MedicineCrohns Disease

Start: 2011-06-30End: 2014-03-31Updated: 2016-02-19

Lipids, Inflammation, and CV Risk in RA

CompletedNCT02714881

Brigham and Women's HospitalCardiovascular Disease, Rheumatoid Arthritis

Start: 2016-10-17End: 2022-12-21Updated: 2026-01-21

Ultrasound Enthesitis Response in Psoriatic Arthritis

CompletedNCT03955861

Belfast Health and Social Care TrustEnthesitis, Psoriasis, Psoriatic Arthritis

Start: 2019-02-14End: 2021-07-17Updated: 2022-02-07

CHronic Nonbacterial Osteomyelitis International Registry

RecruitingNCT04725422

Seattle Children's HospitalChronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal Osteomyelitis

Start: 2018-08-01End: 2050-08-31Target: 2000Updated: 2024-07-30

Related Papers

Nipocalimab, an anti-FcRn monoclonal antibody, in participants with moderate to severe active rheumatoid arthritis and inadequate response or intolerance to anti-TNF therapy: results from the phase 2a IRIS-RA study

RMD Open2024-06-0114 citations

Interplay Between Systemic Inflammation, Myocardial Injury, and Coronary Microvascular Dysfunction in Rheumatoid Arthritis: Results From the LiiRA Study

Journal of the American Heart Association2024-04-3012 citations

Phase I trial of the TNF-α inhibitor certolizumab plus chemotherapy in stage IV lung adenocarcinomas

Nature Communications2022-10-1518 citations

The relationship between the nail and systemic enthesitis in psoriatic arthritis

Rheumatology Advances in Practice2021-01-016 citations

Abstract 15089: Specificity for Inflammatory Pathways and Myocardial Injury Associated With Coronary Microvascular Dysfunction in Rheumatoid Arthritis

Circulation2020-11-121 citations

Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential.

2016-09-0125 citations

A phase I trial of certolizumab plus chemotherapy in patients with stage IV lung adenocarcinomas.

Journal of Clinical Oncology2016-05-20