capsule
Sponsors
Nanfang Hospital, Southern Medical University, Morphic Therapeutic Inc., Kartos Therapeutics Inc., Mirum Pharmaceuticals Inc., Acerta Pharma B.V.
Conditions
Advanced or Recurrent Endometrial CancerFibrostenosing Crohn’s DiseaseFungal infectionGastric diseasesMantle Cell LymphomaMetastatic Castration-Resistant Prostate CancerMetastatic Medullary Thyroid CancerModerately to Severely Active Crohn’s Disease
Phase 1
Phase 2
A Phase 2b, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of 3 Active Dose Regimens of MORF-057 in Adults with Moderately to Severely Active Ulcerative Colitis (EMERALD-2)
Active, not recruitingCTIS2022-500953-17-00
Start: 2023-03-23Target: 172Updated: 2025-12-11
A Randomized Double-Blind Placebo-Controlled Study to Evaluate Efficacy and Safety of Volixibat in the Treatment of Cholestatic Pruritus in Patients with Primary Sclerosing Cholangitis (VISTAS)
Active, not recruitingCTIS2023-505764-11-00
Start: 2022-06-10Target: 105Updated: 2025-11-24
A Phase 2/3 Study of Navtemadlin as Maintenance Therapy in Subjects with TP53WT Advanced or Recurrent Endometrial Cancer Who Responded to Chemotherapy
CompletedCTIS2022-502196-31-00
Start: 2023-08-21End: 2024-07-26Target: 140Updated: 2024-05-15
A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of 2 Active Dose Regimens of MORF-057 in Adults with Moderately to Severely Active Crohn’s Disease (GARNET)
RecruitingCTIS2023-508158-24-00
Start: 2024-06-25Target: 150Updated: 2025-12-02
TSPO ligands in the treatment of depression: proof-of-concept of efficacy and underlying mechanisms of action
CompletedCTIS2024-512698-29-00
Start: 2024-07-25End: 2025-11-21Target: 50Updated: 2025-06-26
The effect of amantadine as add-on therapy for motor fluctuations in advanced Parkinson’s disease: a randomized double-blinded placebo-controlled trial
RecruitingCTIS2023-509728-16-00
Start: 2025-10-10Target: 132Updated: 2026-01-23
A trial of prednisolone in combination with SPI-62 or placebo in participants with polymyalgia rheumatica (PMR)
CompletedCTIS2024-517406-29-00
Start: 2022-07-26End: 2025-04-25Target: 72Updated: 2025-02-14
A Phase 2b, Randomized, Placebo-controlled, Double-blind, Dose-ranging Trial to Assess the Efficacy and Safety of Ontunisertib in Patients with Fibrostenosing Crohn’s Disease
Not yet recruitingCTIS2026-525197-19-00
Target: 33Updated: 2026-09-22
Phase 3
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined with Abiraterone Acetate and Prednisone (AA-P) versus Placebo Combined with AA-P as First-Line Treatment in Patients with Metastatic Castration-Resistant Prostate Cancer
Active, not recruitingCTIS2023-509396-16-00
Start: 2021-11-08Target: 136Updated: 2025-12-05
A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study of Bendamustine and Rituximab (BR) Alone Versus in Combination with Acalabrutinib (ACP-196) in Subjects with Previously Untreated Mantle Cell Lymphoma
Active, not recruitingCTIS2023-509354-58-00
Start: 2017-07-14Target: 198Updated: 2025-07-29
A Phase 3, Randomized, Double-blind, Add-on Study Evaluating the Safety and Efficacy of Navtemadlin Plus Ruxolitinib vs Placebo Plus Ruxolitinib in Patients with Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
RecruitingCTIS2023-504724-25-00
Start: 2024-10-16Target: 126Updated: 2025-10-06
Phase 4
Pharmacokinetics of fluconazole given orally or intravenously as prophylaxis or therapy to children and adolescents with invasive fungal infections (FOCUS)
Not yet recruitingCTIS2024-518305-17-01
Target: 30Updated: 2024-12-02
A Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Cabozantinib (XL184) at 60 mg/Day Compared to 140 mg/Day in Progressive, Metastatic Medullary Thyroid Cancer Patients
Active, not recruitingCTIS2024-516480-90-00
Start: 2015-11-23Target: 10Updated: 2025-12-17
Unknown Phase
Standing type magnetically guided capsule versus gastroscopy for gastric examination
Active, not recruitingChiCTR1800018346
Start: 2018-04-17Updated: 2018-09-17
A Prospective, Randomized, Placebo-controlled, Double-blind Study to Assess the Efficacy of Bacillus Coagulans Unique IS2 on Improving Bowel Movement Characteristics, Gastrointestinal-related Symptoms and Quality of Life in Healthy Adult Participants
CompletedNCT05123664
Start: 2022-04-11End: 2023-12-20Updated: 2024-03-06