Brain PET scan

PROCEDURE13 trials

Sponsors

Avid Radiopharmaceuticals

Conditions

Alzheimer DiseaseAlzheimer's DiseaseCognitive DeclineCorticobasal DegenerationDepressionFrontotemporal DementiaMild Cognitive ImpairmentProgressive Supranuclear Palsy

Early Phase 1

Exploratory Evaluation of Flortaucipir Injection in Healthy Volunteers and Cognitively Impaired Subjects

CompletedNCT04474405

Avid RadiopharmaceuticalsAlzheimer Disease

Start: 2013-08-16End: 2013-12-09Updated: 2020-09-25

Phase 1

A Study of Flortaucipir PET in Healthy Volunteers and Cognitively Impaired Subjects

CompletedNCT01992380

Avid RadiopharmaceuticalsAlzheimer's Disease

Start: 2013-11-13End: 2014-05-30Updated: 2020-09-07

Tau Imaging in Subjects With Progressive Supranuclear Palsy, Corticobasal Degeneration and Healthy Volunteers

CompletedNCT02167594

Avid RadiopharmaceuticalsCorticobasal Degeneration, Progressive Supranuclear Palsy

Start: 2014-08-12End: 2016-07-11Updated: 2020-08-28

Tau Imaging in Professional Fighters

CompletedNCT02278354

Avid RadiopharmaceuticalsAlzheimer's Disease

Start: 2015-02-18End: 2017-02-03Updated: 2020-09-10

Flortaucipir PET Imaging in Subjects With FTD

CompletedNCT03040713

Avid RadiopharmaceuticalsFrontotemporal Dementia

Start: 2017-04-11End: 2018-10-24Updated: 2020-09-25

Flortaucipir 18F PET Imaging in BIOCARD Study

TerminatedNCT03052972

Avid RadiopharmaceuticalsCognitive Decline

Start: 2017-03-23End: 2018-08-17Updated: 2020-09-25

Flortaucipir PET Imaging in the Preclinical, Prodromal and Dementia Phases of Alzheimer's Disease

CompletedNCT04468347

Avid RadiopharmaceuticalsAlzheimer Disease, Mild Cognitive Impairment

Start: 2014-10-31End: 2018-02-28Updated: 2020-09-25

Phase 2

Analysis of 18F-AV-1451 PET Imaging in Cognitively Healthy, MCI, and AD Subjects

CompletedNCT02016560

Avid RadiopharmaceuticalsAlzheimer's Disease

Start: 2013-12-31End: 2017-07-28Updated: 2020-09-22

Imaging Characteristics of a Follow-up 18F-AV-1451 Scan

TerminatedNCT02051764

Avid RadiopharmaceuticalsAlzheimer's Disease

Start: 2014-05-31End: 2016-12-31Updated: 2020-09-07

Clinical Evaluation of Flortaucipir F 18

CompletedNCT02278367

Avid RadiopharmaceuticalsAlzheimer's Disease, Depression, Traumatic Brain Injury

Start: 2014-12-31End: 2019-06-26Updated: 2020-09-10

Tau Screening Study in Patients With Early Symptomatic AD

CompletedNCT03322462

Avid RadiopharmaceuticalsAlzheimer Disease

Start: 2017-11-21End: 2018-08-31Updated: 2020-08-24

Tau Screening Study in Subjects With Early Symptomatic AD

CompletedNCT03467477

Avid RadiopharmaceuticalsAlzheimer Disease

Start: 2018-03-08End: 2018-11-15Updated: 2020-08-24

Phase 3

Evaluation of Flortaucipir PET Signal and Cognitive Change in Early Alzheimer's Disease

CompletedNCT03901105

Avid RadiopharmaceuticalsAlzheimer Disease

Start: 2019-03-28End: 2019-04-28Updated: 2020-08-28

Related Papers

18F-flortaucipir PET imaging: Biodistribution in the Japanese population and diagnostic accuracy by Japanese readers

Annals of Nuclear Medicine2026-07-17

Quantitative‐ and visual read‐based flortaucipir PET T+ criteria for the pathophysiological assessment of Alzheimer’s Disease

Alzheimer s & Dementia2024-12-01

Tau Positivity for Flortaucipir using a Commercial Tau Quantification Software: Comparison to Visual Interpretation

Alzheimer s & Dementia2024-12-01

A comparison of two novel visual read‐based methods for high tau identification from flortaucipir‐PET

Alzheimer s & Dementia2023-12-011 citations

Distinct associations between tau PET and cognitive impairment across brain regions and cognitive domains in Alzheimer’s disease

Alzheimer s & Dementia2023-12-011 citations

Bayesian network analysis of BIN1 risk allele and other risk factors and biomarkers of Alzheimer’s disease

Alzheimer s & Dementia2023-12-011 citations

To Assess Mediation Effects of BIN1 Risk Variant rs6733839 and APOE4 on Alzheimer’s disease Pathology

Alzheimer s & Dementia2023-12-011 citations

Tau as a diagnostic instrument in clinical trials to predict amyloid in Alzheimer's disease

Alzheimer s & Dementia Translational Research & Clinical Interventions2023-07-0116 citations

Data‐Driven Methods Highlight Early Signals of Tau in Patients Lacking Global Uptake: Facilitating Enrollment in Clinical Trials

Alzheimer s & Dementia2022-12-01

Aggregated Tau Measured by Visual Interpretation of Flortaucipir Positron Emission Tomography and the Associated Risk of Clinical Progression of Mild Cognitive Impairment and Alzheimer Disease

JAMA Neurology2021-02-1553 citations