Benazepril

DRUG11 trials

Conditions

ACE InhibitorAngiotensin II Type 1 Receptor BlockersChronic Kidney FailureDiabetesDiabetes MellitusDilated CardiomyopathyDisease ProgressionDose-Response Relationship,Drug

Phase 2

A multi-center, randomized, placebo- and active-controlled, parallel-group, 24-week proof of concept and dose-finding study to evaluate efficacy, safety, and tolerability of XXB750 in patients with heart failure

CompletedCTIS2023-504678-39-00

Novartis Pharma AGHeart Failure

Start: 2024-03-13End: 2024-11-08Target: 424Updated: 2024-11-08

Phase 3

Preventing ESRD in Overt Nephropathy of Type 2 Diabetes

CompletedNCT00494715

Mario Negri Institute for Pharmacological ResearchDiabetes

Start: 2007-05-31End: 2016-04-30Updated: 2016-06-01

Preventing Microalbuminuria in Type 2 Diabetes

CompletedNCT00503152

Mario Negri Institute for Pharmacological ResearchDiabetes

Start: 2007-05-31End: 2016-09-30Updated: 2019-09-06

Phase 4

Treatment of High Blood Pressure Using Olmesartan With Hydrochlorothiazide Compared to an ACE Inhibitor With a Calcium Channel Blocker

CompletedNCT00185120

Daiichi SankyoHypertension

Start: 2005-09-30End: 2006-09-30Target: 152Updated: 2012-01-18

Comparison Between Losartan and Benazepril in Diabetic Hypertensive Patients Not Controlled by Amlodipine

CompletedNCT01603940

Hospital Universitario Pedro ErnestoDiabetes Mellitus, Hypertension

Start: 2012-05-31End: 2015-01-31Updated: 2016-02-01

Supramaximal Titrated Inhibition of RAAS in Dilated Cardiomyopathy

CompletedNCT01917149

Xijing HospitalDilated Cardiomyopathy

Start: 2005-03-31End: 2013-12-31Updated: 2014-05-19

Unknown Phase

Benazepril for Advanced Chronic Renal Insufficiency

TerminatedNCT00270426

Southern Medical University, ChinaChronic Kidney Failure

Updated: 2006-05-05

Long-Term Renoprotection of Optimal Antiproteinuric Doses of Benazepril and Losartan in Chronic Renal Insufficiency

TerminatedNCT00338091

Southern Medical University, ChinaACE Inhibitor, Angiotensin II Type 1 Receptor Blockers, Disease Progression +3

Start: 2002-01-31End: 2006-05-31Updated: 2006-06-20

Safety of Dual Blockage of Rennin-angiotensin System in Patients With Advanced Renal Insufficiency

TerminatedNCT00630708

Nanfang Hospital, Southern Medical UniversityRenal Insufficiency, Chronic

Start: 2008-02-29End: 2014-03-31Target: 309Updated: 2016-04-05

Renal Protective Effects of Renin Angiotensin System (RAS) Inhibitor in Peritoneal Dialysis Patients

CompletedNCT00721773

Sun Yat-sen UniversityRenal Function Disorder

Start: 2008-09-30End: 2014-10-31Updated: 2015-05-20

Low Dose Versus Aggressive Inhibition of the Renin-Angiotensin-Aldosterone (RAS) to Treat Microalbuminuria

CompletedNCT00907374

Charles Drew University of Medicine and ScienceMicroalbuminuria

Start: 2005-07-31End: 2009-04-30Updated: 2012-03-30

Clinical Journal of the American Society of Nephrology2022-11-2272 citations

Preventing microalbuminuria with benazepril, valsartan, and benazepril–valsartan combination therapy in diabetic patients with high-normal albuminuria: A prospective, randomized, open-label, blinded endpoint (PROBE) study

PLoS Medicine2021-07-1411 citations

Efficacy and Safety of Supramaximal Titrated Inhibition of Renin-Angiotensin-Aldosterone System in Idiopathic Dilated Cardiomyopathy

ESC Heart Failure2015-07-1415 citations