Axillary Lymph Node Dissection

PROCEDURE17 trials

Sponsors

Alliance for Clinical Trials in Oncology, European Organisation for Research and Treatment of Cancer - EORTC, ETOP IBCSG Partners Foundation, University of Miami, Institut du Cancer de Montpellier - Val d'Aurelle

Conditions

Breast CancerBreast Cancer Stage IBreast Cancer Stage IIBreast Cancer Stage IIIBreast CarcinomaBreast Carcinoma Metastatic in Lymph NodeBreast NeoplasmsBreast Surgery

Phase 1

Axillary Lymph Node Preservation Surgery in Reducing Lymphedema in Patients With Breast Cancer

TerminatedNCT00932035

City of Hope Medical CenterBreast Cancer

Start: 2009-06-30End: 2014-05-31Updated: 2017-06-07

Phase 2

Surgery to Remove the Sentinel Lymph Node and Axillary Lymph Nodes After Chemotherapy in Treating Women With Stage II, Stage IIIA, or Stage IIIB Breast Cancer

CompletedNCT00881361

Alliance for Clinical Trials in OncologyBreast Cancer

Start: 2009-07-31End: 2023-04-15Updated: 2023-04-27

Axillary Reverse Mapping

CompletedNCT01381315

University of Kansas Medical CenterBreast Cancer

Start: 2009-09-30End: 2016-05-31Updated: 2017-01-10

Internal Mammary Sentinel Lymph Node Biopsy in Early Breast Cancer Patients With Clinically Axillary Node -Negative

CompletedNCT01642511

Shandong Cancer Hospital and InstituteBreast Cancer

Start: 2012-01-31End: 2015-03-31Updated: 2018-04-04

Enzalutamide and Paclitaxel Before Surgery in Treating Patients With Stage I-III Androgen Receptor-Positive Triple-Negative Breast Cancer

CompletedNCT02689427

M.D. Anderson Cancer CenterInvasive Breast Carcinoma, Stage IA Breast Cancer AJCC v7, Stage IB Breast Cancer AJCC v7 +9

Start: 2016-09-22End: 2023-11-15Updated: 2024-09-19

Phase 3

Lymph Node Removal in Treating Women Who Have Stage I or Stage IIA Breast Cancer

CompletedNCT00003855

Alliance for Clinical Trials in OncologyBreast Cancer

Start: 1999-04-30End: 2011-02-28Updated: 2020-04-29

Comparison of Complete Axillary Lymph Node Dissection With Axillary Radiation Therapy in Treating Women With Invasive Breast Cancer

CompletedNCT00014612

European Organisation for Research and Treatment of Cancer - EORTCBreast Cancer

Start: 2001-02-28End: 2013-03-31Updated: 2013-10-29

Axillary Lymph Node Dissection Versus no Dissection in Breast Cancer With Positive Sentinel Lymph Node

WithdrawnNCT01796444

Shandong Cancer Hospital and InstituteBreast Cancer

Start: 2013-01-31End: 2026-06-30Updated: 2018-04-05

Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection

Active, not recruitingNCT03927027

Alliance for Clinical Trials in OncologyBreast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III

Start: 2019-07-29End: 2027-01-01Updated: 2026-01-26

Phase 4

Selective Lymph Node Dissection Using Fluorescent Dye in Node-positive Breast Cancer

Samsung Medical CenterBreast Neoplasms

Start: 2016-05-31End: 2017-04-30Target: 150Updated: 2016-09-20

Magseed Magnetic Marker in Locating Axillary Lymph Nodes in Patients With Breast Cancer Undergoing Surgery

CompletedNCT03038152

M.D. Anderson Cancer CenterBreast Carcinoma Metastatic in Lymph Node, Stage IIA Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7 +3

Start: 2017-04-11End: 2021-03-01Updated: 2021-03-05

Unknown Phase

Surgical Resection With or Without Axillary Lymph Node Dissection in Treating Women With Node-Negative Breast Cancer and Sentinel Lymph Node Micrometastases

CompletedNCT00072293

ETOP IBCSG Partners FoundationBreast Cancer

Start: 2001-12-31End: 2017-03-31Updated: 2018-01-23

Thoracoscopic Sentinel Lymph Node Biopsy in Patients With Stage I or Stage II Breast Cancer

CompletedNCT00450723

University of MiamiBreast Cancer

Start: 2004-05-31End: 2011-03-31Updated: 2017-02-07

Radiation Therapy During Surgery in Treating Older Women With Stage I Breast Cancer

CompletedNCT00556777

Institut du Cancer de Montpellier - Val d'AurelleBreast Cancer

Start: 2004-04-19End: 2008-12-31Updated: 2025-03-06

Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy

RecruitingNCT04109079

University Hospitals of Derby and Burton NHS Foundation TrustBreast Cancer, Neoplasm, Breast, Sentinel Lymph Node

Start: 2021-02-26End: 2030-02-28Target: 1900Updated: 2026-03-30

Axillary Node Dissection w or w/o LVB in Node Positive Breast Cancer Patients

Not yet recruitingNCT05970107

Case Comprehensive Cancer CenterNode-positive Breast Cancer

Start: 2026-06-01End: 2028-12-01Target: 400Updated: 2026-02-19

Omission of Axillary Lymph Node Dissection in Case of Tumor Spread to Lymph Nodes in the Armpit in Breast Cancer

Not yet recruitingNCT06869629

Karolinska InstitutetBreast Cancer, Breast Carcinoma, Breast Surgery

Start: 2026-01-01End: 2040-12-31Target: 1380Updated: 2025-12-05

Related Papers

Omission of axillary lymph node dissection in patients with breast cancer with axillary pathological complete response confirmed by stained region lymph node biopsy after neoadjuvant systemic therapy (SrLNB study): study protocol for a single-arm, single-centre, phase-II trial

BMJ Open2025-03-01

Node marking techniques and targeted axillary dissection in patients with cN1 disease undergoing neoadjuvant chemotherapy: Analysis of initial 500 participants in the ATNEC trial.

Journal of Clinical Oncology2024-06-01

Practice patterns in ongoing neoadjuvant ATNEC trial for patients with cT1-3N1M0 breast cancer: Response to neoadjuvant chemotherapy (NACT), targeted axillary dissection and breast conservation rates.

Journal of Clinical Oncology2023-06-01

Abstract OT1-09-02: ATNEC: A multicentre, randomized trial investigating whether axillary treatment can be avoided in T1-3N1M0 breast cancer patients with no residual cancer in the axillary lymph nodes after neoadjuvant chemotherapy

Cancer Research2023-03-012 citations

ATNEC: A multicenter, randomized trial investigating whether axillary treatment can be avoided in patients with T1-3N1M0 breast cancer with no residual cancer in the lymph glands after neoadjuvant chemotherapy.

Journal of Clinical Oncology2022-06-019 citations

Exercise versus usual care after non-reconstructive breast cancer surgery (UK PROSPER): multicentre randomised controlled trial and economic evaluation

BMJ2021-11-1068 citations

Axillary management in T1-3N1M0 breast cancer patients with needle biopsy proven nodal metastases at presentation after neoadjuvant chemotherapy (ATNEC).

Journal of Clinical Oncology2021-05-204 citations

Surgical Management of the Axilla in Clinically Node-Positive Breast Cancer Patients Converting to Clinical Node Negativity through Neoadjuvant Chemotherapy: Current Status, Knowledge Gaps, and Rationale for the EUBREAST-03 AXSANA Study.

2021-03-29112 citations

Abstract OT-04-01: Axillary management in T1-3N1M0 breast cancer patients with needle biopsy proven nodal metastases at presentation after neoadjuvant chemotherapy - ATNEC (ClinicalTrials.gov NCT04109079)

Cancer Research2021-02-151 citations

Multidisciplinary considerations in the treatment of triple‐negative breast cancer

CA A Cancer Journal for Clinicians2020-09-2815 citations

Comprehensive profiling of androgen receptor-positive (AR+) triple-negative breast cancer (TNBC) patients (pts) treated with standard neoadjuvant therapy (NAT) +/- enzalutamide.

Journal of Clinical Oncology2020-05-2011 citations

Evaluation of predictive biomarkers for AR therapy and to identify the LAR subtype of TNBC.

Journal of Clinical Oncology2019-05-20

Tailored axillary surgery with or without axillary lymph node dissection followed by radiotherapy in patients with clinically node-positive breast cancer (TAXIS): study protocol for a multicenter, randomized phase-III trial.

2018-12-04108 citations

Axillary dissection versus no axillary dissection in patients with breast cancer and sentinel-node micrometastases (IBCSG 23-01): 10-year follow-up of a randomised, controlled phase 3 trial.

2018-09-05363 citations

Lymphedema symptoms and limb measurement changes in breast cancer survivors treated with neoadjuvant chemotherapy and axillary dissection: results of American College of Surgeons Oncology Group (ACOSOG) Z1071 (Alliance) substudy.

2018-07-0664 citations

Factors associated with lymphedema in patients/women with node positive breast cancer treated with neoadjuvant chemotherapy and axillary dissection on a prospective clinical trial.

Journal of Clinical Oncology2018-05-20

Effect of Axillary Dissection vs No Axillary Dissection on 10-Year Overall Survival Among Women With Invasive Breast Cancer and Sentinel Node Metastasis

JAMA2017-09-121760 citations

Ten-year survival results of ACOSOG Z0011: A randomized trial of axillary node dissection in women with clinical T1-2 N0 M0 breast cancer who have a positive sentinel node (Alliance).

Journal of Clinical Oncology2016-05-2013 citations

[Internal mammary sentinel lymph node biopsy in breast cancer: accurate staging and individualized treatment].

PubMed2016-01-01

Effect of the use of immediate reconstruction on the rates of bilateral mastectomy and adjuvant radiation therapy use in women with node-positive breast cancer treated with neoadjuvant chemotherapy on ACOSOG Z1071 (Alliance).

Journal of Clinical Oncology2015-05-201 citations

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