Antiarrhythmic drug

DRUG13 trials

Sponsors

Biosense Webster, Inc., Hospital Clinic of Barcelona, Valley Health System, University of Rostock, Yonsei University

Conditions

Antiarrhythmic ToxicityArrhythmiaAtrial FibrillationAtrial Fibrillation (AF)Atrial Fibrillation New OnsetAtrial FlutterCardiovascular DiseasesCatheter Ablation

Phase 3

NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation

CompletedNCT00116428

Biosense Webster, Inc.Arrhythmia, Atrial Fibrillation, Heart Diseases

Start: 2004-10-01End: 2011-03-01Updated: 2017-10-24

Continuation of Antiarrhythmics Following Ventricular Tachycardia Catheter Ablation

TerminatedNCT04208997

Vanderbilt University Medical CenterCatheter Ablation, Tachycardia, Ventricular

Start: 2019-12-19End: 2021-06-30Updated: 2022-11-14

Phase 4

Study of Ablation Versus antiaRrhythmic Drugs in Persistent Atrial Fibrillation

CompletedNCT00863213

Hospital Clinic of BarcelonaAtrial Fibrillation

Start: 2009-03-31End: 2012-12-31Updated: 2013-04-26

Catheter Ablation for Recently Diagnosed Paroxysmal Atrial Fibrillation

WithdrawnNCT01505296

Valley Health SystemAtrial Fibrillation

Start: 2011-12-31End: 2014-01-31Updated: 2014-12-16

CRyoAblation vs AntiaRrhythmic Drugs for Persistent Atrial Fibrillation Trial

CompletedNCT03716934

Hospital San Carlos, MadridAtrial Fibrillation

Start: 2018-06-27End: 2022-04-18Updated: 2025-09-15

Unknown Phase

Therapy of Atrial Flutter by Afib Ablation

University of RostockAtrial Fibrillation, Atrial Flutter

Start: 2010-08-31End: 2017-08-31Target: 100Updated: 2014-01-31

Prospective Randomized Clinical Trial for Effect of Stellate Ganglion Block in Medically Refractory Ventricular Tachycardia

Yonsei UniversityRefractory Ventricular Tachycardia

Start: 2019-03-31End: 2019-09-30Target: 20Updated: 2019-02-11

STOP AF First: Cryoballoon Catheter Ablation in an Antiarrhythmic Drug Naive Paroxysmal Atrial Fibrillation

CompletedNCT03118518

Medtronic Cardiac Ablation SolutionsAtrial Fibrillation, Atrial Fibrillation New Onset

Start: 2017-06-23End: 2020-06-25Updated: 2025-02-13

Trial to Evaluate the Efficacy and Safety of Substrate Ablation of Monomorphic Ventricular Tachycardia

CompletedNCT03734562

Hospital General Universitario Gregorio MarañonMonomorphic Ventricular Tachycardia

Start: 2010-07-31End: 2017-09-30Updated: 2019-03-15

Use of Antiarrhythmic Drugs in Pediatrics

Assiut UniversityAntiarrhythmic Toxicity

Start: 2021-10-01End: 2022-10-01Target: 100Updated: 2021-05-06

EfFect of Ablation of Persistent AtriaL Fibrillation on COgNitive Function in Individuals With Mild Cognitive Impairment

RecruitingNCT05790707

Poitiers University HospitalMild Cognitive Impairment, Persistent Atrial Fibrillation

Start: 2023-04-21End: 2027-07-01Target: 120Updated: 2026-01-23

MANAGE-VT Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry

RecruitingNCT06455488

CorVita Science FoundationVentricular Tachycardia

Start: 2020-07-20End: 2030-07-20Target: 130Updated: 2024-06-12

The Safety and Efficacy of Pulsed Field Ablation for Patients With Persistent Atrial Fibrillation Comorbid With HFpEF.

Enrolling by invitationNCT07077811

Affiliated Hospital of Nantong UniversityAtrial Fibrillation (AF), Cardiovascular Diseases, Heart Failure +1

Start: 2025-06-01End: 2028-06-01Target: 158Updated: 2025-07-22

Related Papers

The Cost-Effectiveness of First-Line Cryoablation vs First-Line Antiarrhythmic Drugs in Canadian Patients With Paroxysmal Atrial Fibrillation.

2023-11-236 citations

An economic evaluation of first-line cryoballoon ablation versus antiarrhythmic drug therapy for the treatment of paroxysmal atrial fibrillation from a German healthcare service payer perspective

European Heart Journal2023-11-012 citations

An economic evaluation of first-line cryoballoon ablation vs antiarrhythmic drug therapy for the treatment of paroxysmal atrial fibrillation from a U.S. Medicare perspective

Heart Rhythm O22023-07-2713 citations

Bayesian analysis of the Substrate Ablation vs. Antiarrhythmic Drug Therapy for Symptomatic Ventricular Tachycardia trial

EP Europace2023-06-277 citations

Substrate Ablation vs Antiarrhythmic Drug Therapy for Symptomatic Ventricular Tachycardia.

2022-04-01117 citations

Cryoballoon Ablation as Initial Therapy for Atrial Fibrillation.

2020-11-16445 citations

Catheter ablation vs. antiarrhythmic drug treatment of persistent atrial fibrillation: a multicentre, randomized, controlled trial (SARA study)

European Heart Journal2013-10-17388 citations

Catheter Ablation Yields Greater Benefits Than Drugs in SARA Study

MD Conference Express2013-08-01

Improvements in symptoms and quality of life in patients with paroxysmal atrial fibrillation treated with radiofrequency catheter ablation versus antiarrhythmic drugs.

2010-10-1299 citations

Comparison of antiarrhythmic drug therapy and radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation: a randomized controlled trial.

2010-01-01870 citations