Anti-VEGF
Sponsors
Allergan, Tyrogenex, Ocular Therapeutix, Inc., Wenzhou Medical University, Johns Hopkins University
Conditions
AMDAge-Related Macular DegenerationAge-Related Macular Degeneration (AMD)Anti-VEGFBranch Retinal Vein OcclusionCardiac ToxicityColorectal AdenocarcinomasDiabetic Macular Edema
Phase 1
CLN-0046: Treatment of AMD Subjects With OTX-TKI
CompletedNCT03630315
Start: 2019-02-18End: 2024-01-10Updated: 2024-07-10
Study to Test the Safety and Tolerability of PF-07062119 in Patients With Selected Advanced or Metastatic Gastrointestinal Tumors.
TerminatedNCT04171141
Start: 2019-11-19End: 2023-11-28Updated: 2025-01-16
Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD
CompletedNCT04626128
Start: 2020-12-15End: 2022-10-13Updated: 2023-09-18
Phase 2
X-82 to Treat Age-related Macular Degeneration
TerminatedNCT02348359
Start: 2015-03-16End: 2018-01-12Updated: 2022-02-11
BITS-TO-HCC Study: HAIC+Iparomlimab/Tuvonralimab + Bevacizumab + SBRT for BCLC-C HCC With PVTT and/or Oligometastases
RecruitingNCT07062055
Start: 2025-07-25End: 2029-07-25Target: 54Updated: 2026-04-01
Unknown Phase
A Retrospective Study of Anti-Vascular Endothelial Growth Factor (VEGF) Injections for Retinal Vein Occlusion or Diabetic Macular Edema
CompletedNCT01918371
Start: 2013-08-02End: 2014-09-04Updated: 2019-04-18
Anti-VEGF Instead of Intraoperative PRP in Proliferative Diabetic Retinopathy
NCT03633266
Start: 2018-09-01End: 2022-12-01Target: 220Updated: 2018-08-17
Anti-VEGF Instead of Intraoperative Fan-shaped Photocoagulation in BRVO Combined With Vitreous Hemorrhage
NCT03637283
Start: 2018-10-01End: 2021-12-01Target: 100Updated: 2018-08-17
Anti-VEGF Therapy for Subfoveal Hemorrhage in Patients With Neovascular Age-Related Macular Degeneration
TerminatedNCT03699618
Start: 2019-05-29End: 2020-01-06Updated: 2020-02-19
Influence of Systemic Parameters in Diabetic Macular Edema - LIPSIA Study
NCT03762226
Start: 2018-09-01End: 2021-12-31Target: 100Updated: 2018-12-03
Effects of Anti-VEGF Targeted Drugs on Patients' Blood Pressure and Endothelial Function
NCT04962438
Start: 2019-07-05End: 2021-12-30Target: 30Updated: 2021-07-15
A Study on the Treatment Strategy of NVG Secondary to PDR
CompletedNCT05156021
Start: 2021-12-12End: 2022-12-31Updated: 2023-08-21
Seven-year Outcomes Following Intensive Anti-VEGF Therapy in Wet AMD
CompletedNCT05678517
Start: 2010-01-01End: 2022-12-06Updated: 2023-01-10
Efficacy Analysis of Anti-VEGF Drugs Combined With Micropulse Laser in the Treatment of Diabetic Macular Edema
NCT05759884
Start: 2022-02-01End: 2024-06-30Target: 40Updated: 2023-03-08
Anti-PD-1/PD-L1 Antibodies Plus Anti-VEGF Antibody Treatment in Patients With Advanced-Stage HCC
RecruitingNCT06537908
Start: 2024-08-01End: 2029-12-31Target: 50Updated: 2025-12-15