This randomized comparative clinical study enrolled adult patients aged 18-80 years with Wagner-Meggitt grade 1-3 DFUs. Participants received either SOC wound management or SOC without topical anibiotic plus LTAPP using a standardized protocol. Patients were followed for up to 16 weeks or until healing/coverage. Outcomes included healed wounds, wound area reduction, wound volume reduction, exudate reduction, granulation tissue formation, necrotic tissue reduction, bacterial load reduction, time
Conditions
Interventions
Both groups received standard wound management, including wound cleansing with normal saline and debridement when clinically indicated. Dressing selection was determined by wound exudate level and inf
standard of wound care ,LTAPP
Sponsors
Thailand center of excellence for life science
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.diabetic foot patients age 18-8 yrs
Exclusion criteria
Exclusion criteria: 1. severe underlying disease such as CKD, sepsis 2.patients can not complete treatment 3.cancer patients 4.previous RT or on immunosuppressive drug 5.pregnancy or breast feeding 6.patients receive other treatment 7.patients had coagulopathy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| wound healing every 2 wk until visit 10 cmsqure/ and calculate by program | — |
Secondary
| Measure | Time frame |
|---|---|
| bacterial reduction every 2 wk until visit 10 few, moderated /culture report ,cost effective at 16th weeks US dollar / total cost in data sheet record | — |
Countries
Thailand
Contacts
Public Contactatthawit mongkornwong
prince of sonkla university
Outcome results
None listed