Patients enrolled in this study must be age over 18 years and were diagnosed with CCD by neurologists according to the diagnostic criteria. Patients with significant cognitive impairment, secondary dystonia, generalized dystonia, focal limb dystonia, deep brain stimulation, and illiteracy were excluded from the study. The patient should not been treated with BoTN injection within the last 3 months prior to the first assessment. Craniocervical dystonia, dystonia, non-motor symptoms
Conditions
Interventions
Botulinum toxin injections were administered to affected craniofacial or cervical muscles. Patients were assessed before and one month after injection for changes in non-motor symptoms, quality of lif
Experimental Procedure/Surgery
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Participants who 1. visited the Botulinum Toxin (BoNT) clinic at Thammasat University Hospital between January and December 2023 2. were aged over 18 years 3. were diagnosed with craniocervical dystonia (CCD) by neurologists according to established diagnostic criteria
Exclusion criteria
Exclusion criteria: Patients 1. with significant cognitive impairment 2. with secondary dystonia 3. with generalized dystonia 4. with focal limb dystonia 5. who had undergone deep brain stimulation 6. who were illiterate 7. who had recieved with BoTN injection within the last 3 months prior to the first assessment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Validation of TU-NMSQuest (construct and concurrent validity) at baseline Spearman rank correlation | — |
Secondary
| Measure | Time frame |
|---|---|
| Efficacy of BoTN injection on non-motor symptoms of CCD 1 month after botulinum toxin injection McNemar test | — |
Countries
Thailand
Contacts
Public ContactPraween Lolekha
Thammasat University
Outcome results
None listed