Botulinum toxin injection

DRUG20 trials

Sponsors

Cliniques universitaires Saint-Luc- Université Catholique de Louvain, Meshalkin Research Institute of Pathology of Circulation, University Hospital, Clermont-Ferrand, Johns Hopkins University, University of Florida

Conditions

Activity of Daily LivingAtrial FibrillationBlepharospasmBotulismBruxismCerebral PalsyCervical Dystonia, PrimaryChronic Exertional Compartment Syndrome

Phase 2

Botulinum Toxin Injection in Epicardial Fat Pads To Treat Atrial Fibrillation After Cardiac Surgery

CompletedNCT01842529

Meshalkin Research Institute of Pathology of CirculationIndications for CABG, Paroxysmal Atrial Fibrillation

Start: 2012-09-30End: 2013-12-31Updated: 2014-01-31

Botulinum Toxin Injection for Preventing Secondary Atrial Fibrillation in Patient With Supra-ventricular Tachyarrythmias

Meshalkin Research Institute of Pathology of CirculationSupra-ventricular Tachyarrhythmias

Start: 2013-06-30End: 2016-02-29Target: 60Updated: 2015-09-23

Botulinum Toxin Injection Into Epicardial Fat Pads to Prevent Atrial Fibrillation in Patients Undergoing Cardiac Surgery

Meshalkin Research Institute of Pathology of CirculationAtrial Fibrillation

Start: 2015-09-30End: 2018-03-31Target: 170Updated: 2017-09-08

Partial Blocks of Rectus Femoris and Soleus With Botulinum Toxin Type A (Xeomin®) to Improve Gait in Hemiparesis

Assistance Publique - Hôpitaux de ParisHemiparesis After Stroke, Traumatic Brain Injury

Start: 2014-12-31End: 2018-12-31Target: 66Updated: 2017-04-19

Comparison of Non-Surgical Treatment Options for Chronic Exertional Compartment Syndrome (CECS)

CompletedNCT04409600

Walter Reed National Military Medical CenterChronic Exertional Compartment Syndrome

Start: 2020-11-05End: 2024-12-06Updated: 2026-03-06

Phase 3

Efficacy Study of Selective Tibial Neurotomy in the Treatment of the Spastic Equinovarus Foot Among Adult Hemiplegic Patients

CompletedNCT00825097

Cliniques universitaires Saint-Luc- Université Catholique de LouvainSpastic Equinovarus Foot, Stroke

Start: 2008-10-31End: 2011-12-31Updated: 2011-12-23

Efficacy of Botulinum Toxin A in the Treatment of Bruxism-related Symptomatology

TerminatedNCT04722809

Centre Hospitalier Universitaire DijonBruxism

Start: 2022-05-25End: 2022-08-31Updated: 2024-08-26

Botulinum Toxin Injection After Sternotomies to Improve Scar Aspect and Impact

Not yet recruitingNCT07013240

University Hospital, BordeauxSternotomy Closure,Open Heart Surgery

Start: 2025-07-05End: 2027-02-28Target: 50Updated: 2025-06-10

Phase 4

EMG-Based Evaluation of Occlusal Splint and Masseter Botox Effects on Head and Neck Muscles

RecruitingNCT07082972

Istanbul UniversityMasticatory Muscle Pain, Myofascial Pain Syndrome (MPS)

Start: 2025-09-01End: 2026-12-01Target: 56Updated: 2025-07-24

Validation of TU-NMS questionnaire, prevalence, and benefit of botulinum toxin injection on non-motor symptoms in primary craniocervical dystonia

Active, not recruitingTCTR20251124004

Patients enrolled in this study must be age over 18 years and were diagnosed with CCD by neurologists according to the diagnostic criteria. Patients with significant cognitive impairment, secondary dystonia, generalized dystonia, focal limb dystonia, deep brain stimulation, and illiteracy were excluded from the study. The patient should not been treated with BoTN injection within the last 3 months prior to the first assessment. Craniocervical dystonia, dystonia, non-motor symptoms

Start: 2023-01-01Target: 26Updated: 2026-03-30

Unknown Phase

Effectiveness of Two Techniques in Injection Site Spotting for Botulinum Toxin Injections: Echography or Electro Stimulation.

CompletedNCT01935544

University Hospital, Clermont-FerrandStroke

Start: 2013-11-19End: 2019-02-12Updated: 2019-10-09

Peroral Endoscopic Myotomy Versus Botulinum Toxin Injection in Spastic Esophageal Disorders

WithdrawnNCT02663206

Johns Hopkins UniversityEsophageal Achalasia, Esophageal Motility Disorders, Esophageal Spasm, Diffuse

Start: 2016-09-30End: 2020-07-31Updated: 2018-01-12

Effects of Botulinum Toxin on Muscle and Brain Activity

TerminatedNCT02837185

University of FloridaCervical Dystonia, Primary

Start: 2016-08-31End: 2018-09-26Updated: 2018-09-28

A Pilot Study of the Effect of Botulinum Toxin Type a (Dysport®, Abobotulinum Toxin A) Injection on Changes in Musculotendinous Length and Dynamics of Hamstring Muscles During Gait in Children With Spastic Cerebral Palsy Walking With Excessive Knee Flexion

CompletedNCT02917967

Yonsei UniversityCerebral Palsy

Start: 2016-11-15End: 2018-09-03Updated: 2019-01-16

Pressure and Flow Study Before and After Treatments for EMD. The pFlow Study

Fundacion Miguel ServetEsophageal Motility Disorders, Gastro-esophageal Reflux

Start: 2019-05-15End: 2022-06-30Target: 60Updated: 2019-04-10

Analysis of Gait Before and After Botulinum Toxin Treatment in Patients With Focal Dystonia

CompletedNCT03938363

University Hospital, GrenobleBlepharospasm, Cervical Dystonia, Primary

Start: 2019-10-23End: 2022-06-13Updated: 2025-12-22

Intrapapillary Botulinum Toxin Injection for PREvention of Post-surgical PAncREactic Fistula

RecruitingNCT04220931

Assistance Publique - Hôpitaux de ParisDistal Pancreatectomy, Postoperative Pancreatic Fistula

Start: 2023-03-27End: 2027-03-01Target: 460Updated: 2023-07-10

Using Shear Wave Ultrasound Elastography for Follow up After Anti-spastic Intervention Among Stroke Patients

National Taiwan University HospitalActivity of Daily Living, Botulism, Spasticity, Muscle +2

Start: 2020-09-30End: 2021-12-31Target: 100Updated: 2020-09-16

Evaluation of Tibial Nerve Selective Neurotomy Compared to Botulinum Toxin Injections for Spastic Foot Treatment in Post-stroke Patients According to a Goal-centered Approach

RecruitingNCT05874154

Hospices Civils de LyonPost Stroke Seizure, Spastic Foot

Start: 2024-01-02End: 2027-03-02Target: 60Updated: 2025-07-14

Efficacy of One or Two Botulinum Toxin Injections in the Treatment of Chronic Lateral Epicondylalgia: a Retrospective Study (EPITOX)

Active, not recruitingNCT06765694

University Hospital, BrestLateral Epicondylitis

Start: 2024-11-01End: 2025-10-31Target: 80Updated: 2025-01-09

Related Papers

Agonist and antagonist activation at the ankle monitored along the swing phase in hemiparetic gait.

2021-08-2013 citations

Efficacy of two injection-site localisation techniques for botulinum toxin injections: a single-blind, crossover, randomised trial protocol among adults with hemiplegia due to stroke

BMJ Open2016-11-014 citations

Long-Term Suppression of Atrial Fibrillation by Botulinum Toxin Injection Into Epicardial Fat Pads in Patients Undergoing Cardiac Surgery

Circulation Arrhythmia and Electrophysiology2015-10-21110 citations