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Management of preterm labor based on cervical length: a randomized controlled trial

Management of preterm labor based on cervical length: a randomized controlled trial

Status
Recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250218004
Enrollment
50
Registered
2025-02-18
Start date
2024-01-24
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Singleton pregnancy woman GA 26 to 34 weeks presenting with preterm labor symptoms as premature contraction defined as regular uterine contractions more than4 times in 30 minute monitor by tocography, All woman will receive a transvaginal cervical length (TVCL) measurement and external fetal monitoring by cardiotocograph on admission. if TVCL less than 15mm the patient will be administered antenatal corticosteroid and tocolysis as they are at risk for preterm delivery. If TVCL more than 30

Interventions

expectant group (no interventions for preterm), patient will be managed expectantly and followed up of cervical length will be done ,intervention group woman will be received tocolytics and antenatal
no treatment,intervention

Sponsors

None listed

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. singleton pregnancy, gestational age 26to 33+6 weeks of gestation 2. Admitted to labor and delivery unit due to signs and symptoms of preterm labor defined as more than 4 times in 30 minutes 3. Cervical dilated less than 2 cm and effacement less than 80% with intact membranes 2 4. Age more than 18 years, able to inform consent

Exclusion criteria

Exclusion criteria: 1. Preterm pre-labor ruptured of membranes 2. Multiple gestations 3. Non-reassuring fetal heart rate status at time of admission 4. Non-viable fetus 5. Lethal fetal anomaly 6. Active vaginal bleeding 7. Suspected cervical insufficiency treated by prophylactic cervical cerclage or ultrasound indicated cerclage 8. History of previous classical caesarean section 9. Suspected chorioamnionitis requiring delivery 10. Unstable maternal conditions such as sepsis, preeclampsia with severe feature, hypovolemic shock, hemodynamic unstability 11. Unable to inform consent

Design outcomes

Primary

MeasureTime frame
Undeliver rate 7 days numbers of undelivered/total threatened preterm

Secondary

MeasureTime frame
Tocolytic use during treatment - 2 days Number of tocolytic use/total threaten preterm,gestational age at delivery at delivery days,Birthweight at delivery gram/weight

Countries

Thailand

Contacts

Public ContactSupakorn Chaiyakarn

Ramathibodi hospital

supagornchai.obgcbh@gmail.com0819133454

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026