Dental caries Systemic inflammation Dental caries Systemic inflammation Children SII NLR PLR
Conditions
Interventions
The control group consists of pediatric patients who presented to the Pediatric outpatient clinic at Ataturk University Faculty of Medicine Hospital for routine examinations and laboratory tests. Thes
control group,patient group
Sponsors
Ataturk University
Eligibility
Sex/Gender
All
Age
2 Years to 14 Years
Inclusion criteria
Inclusion criteria: Patient Group (Dental Treatment Group): 1)Pediatric patients without any underlying systemic diseases or medical contraindications. 2)Pediatric patients diagnosed with untreated dental caries. 3)Pediatric patients who underwent dental treatment under general anesthesia. 4)Pediatric patients who presented to Ataturk University Research Hospital between 30.09.2024 and 30.12.2024. Control Group: 1)Children who attended the Pediatric outpatient clinic at Ataturk University Faculty of Medicine Hospital for routine clinical evaluations between 30.09.2024 and 30.12.2024. 2)Children with no dental caries. 3)Age and sex matched to the patient group. 4)Pediatric patients without any underlying systemic diseases
Exclusion criteria
Exclusion criteria: 1) Pediatric patients with a history of systemic diseases, genetic syndromes, or congenital malformations. 2)Patients with current upper respiratory tract infections or those actively undergoing pharmacological treatment. 3)Pediatric patients diagnosed with dental caries (excluded from the control group). 4)Children or parents who opted not to provide informed consent or declined participation in the study. 5)Pediatric patients exhibiting hematological abnormalities, including anemia, polycythemia, leukopenia, leukocytosis, thrombocytopenia, or thrombocytosis, as identified in complete blood count (CBC) analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systemic Inflammation Markers The evaluations will be conducted at the same time as the oral examination and CBC analysis, within the study's predefined time frame for data collection. Systemic inflammation markers (SII, NLR, PLR, NEUT, LYMPH, PLT) will be evaluated via complete blood count (CBC) analysis in children with and without untreated dental caries. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dental Health Indices (dmft/DMFT and pufa/PUFA) The evaluations will be conducted during the oral examination and treatment process, as part of routine assessments on the same day the dental procedure is performed Dental health assessed using the dmft/DMFT index (decayed, missing, and filled teeth) for primary and permanent teeth, and the pufa/PUFA index (pulpal involvement, ulceration, abscess). | — |
Countries
Turkey
Contacts
Public ContactFatma Sarac
Ataturk University
Outcome results
None listed