Osteoarthritis of knee Antiinflammatory, intraarticular corticosteroid, IACS, platelet-rich plasma, PRP, knee osteoarthritis, synovial thickness fold, ultrasonography
Conditions
Interventions
Platelet rich plasma (PRP) prepared by using centrifuged autologous blood to retrieve plasma layer that contained high concentration of platelets. The PRP then are injected into the osteoarthritic kne
Platelet rich plasma(PRP),Intraarticular corticosteroid (IACS)
Sponsors
Department of orthopedic, Phramongkutklao hospital
Thanainit Chotanaphuti
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients who had been diagnosed as osteoarthritis knee according to American college of rheumatology
Exclusion criteria
Exclusion criteria: secondary osteoarthritis knee, inflammatory joint disease, previous knee infection, or previous knee surgery, high risk for injection treatment such as immunocompromised host, on anticoagulants, hemophilia or other bleeding disorders; and susceptibility to platelet dysfunction such as antiplatelet drugs use, low platelet count(<150,000/mm3), or autoimmune disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Synovial thickness 0, 1, 2, 4, 12 week Ultrasound | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analog Scale 0, 1, 2, 4, 12 week Visual analog scale,Functional outcome score 0, 1, 2, 4, 12 week Modified WOMAC score Thai version,Adverse events 0, 1, 2, 4, 12 week Adverse effect after injection | — |
Countries
Thailand
Contacts
Public ContactNatpawee Tanthaprabha
Phramongkutklao hospital
Outcome results
None listed