Experimental Biological/Vaccine,Active Comparator Drug

4 trials

Sponsors

Department of orthopedic, Phramongkutklao hospital, Strategic Wisdom and Research Institute, Medeze Group PCL

Conditions

Osteoarthritis of knee Antiinflammatory, intraarticular corticosteroid, IACS, platelet-rich plasma, PRP, knee osteoarthritis, synovial thickness fold, ultrasonographyPhysician-diagnosed early-stage knee osteoarthritis (Kellgren Lawrence grade II).Chronic knee pain persisting for a minimum of three months. A (WOMAC) pain subscale score more than 40 . early osteoarthritisPlaque type psoriasis Psoriasis, psoriasis vulgaris, plaque type psoriasis, topical postbiotic, cytokineRotator cuff injury Rotator cuff, platelet-rich plasma, PRP, MRI

Phase 1

Phase I Safety Run In and Phase II Randomized Open Label, Blinded Endpoint Trial of Autologous Adipose Derived Mesenchymal Stromal Cells versus Hyaluronic Acid in Early Knee Osteoarthritis.

Active, not recruitingTCTR20251020005

Medeze Group PCLPhysician-diagnosed early-stage knee osteoarthritis (Kellgren Lawrence grade II).Chronic knee pain persisting for a minimum of three months. A (WOMAC) pain subscale score more than 40 . early osteoarthritis

Start: 2025-10-12Target: 75Updated: 2026-08-03

Phase 2

Platelet-rich plasma reduces tear size in partial supraspinatus tendon tears compared to conventional steroid injection

Active, not recruitingTCTR20210428004

Rotator cuff injury Rotator cuff, platelet-rich plasma, PRP, MRI

Start: 2020-05-01Target: 32Updated: 2026-08-03

Efficacy and safety of topical solution from Lactobacillus paracasei MSMC 39-1 compared to topical corticosteroid in the treatment of mild severity chronic plaque type psoriasis

Active, not recruitingTCTR20250227004

Strategic Wisdom and Research InstitutePlaque type psoriasis Psoriasis, psoriasis vulgaris, plaque type psoriasis, topical postbiotic, cytokine

Start: 2025-01-30Target: 30Updated: 2026-08-03

Phase 3

Anti-inflammatory effect of platelet-rich plasma compared with Intraarticular corticosteroid in osteoarthritis knee: A randomized controlled trial

Active, not recruitingTCTR20240728001

Department of orthopedic, Phramongkutklao hospitalOsteoarthritis of knee Antiinflammatory, intraarticular corticosteroid, IACS, platelet-rich plasma, PRP, knee osteoarthritis, synovial thickness fold, ultrasonography

Start: 2022-12-01Target: 80Updated: 2026-08-03

Related Papers

Effects of Platelet-Rich Plasma in Tear Size Reduction in Partial-Thickness Tear of the Supraspinatus Tendon Compared to Corticosteroids Injection.

2023-02-089 citations