Healthy condition Rice, Antioxidant, Antiinflammation, Antiaging, Healthy Volunteers
Conditions
Interventions
All the subjects run in by Consuming Hom Mali Rice 300 g/d for 14 days before Intervention by Tubtim Chumphae Rice 300 g/d for 14 days.,All the subjects run in by Consuming Hom Mali Rice 300 g/d for 1
Tubtim Chumphae Rice,Hom Mali Rice
Sponsors
Program Management Unit Competitiveness (PMUC)
Eligibility
Sex/Gender
All
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Both male and female volunteers, aged between 45-65 years, with normal physical health, that is, no congenital disease and not taking medicine. 2. Has a standard weight Measure body mass index (BMI 18.5-24.9 kg/m2) 3. Assess health status With the Thai version of the General Health Questionnaire (GHQ) assessment, it was within normal limits. 4. Can communicate Can read and write Thai
Exclusion criteria
Exclusion criteria: 1. Have a chronic disease that requires continuous medication, including cardiovascular disease or Clogged arteries from blood clots, lung disease, diseases of the thyroid gland, adrenal gland, pituitary gland, cancer, diabetes, allergies, liver disease, and a history of brain injury. 2. Take fat-reducing medicine, Blood sugar lowering medicine, Blood pressure lowering drugs or drugs that interfere with platelet function, such as aspirin and nonsteroidal anti-inflammatory drugs. 3. Take other dietary supplements that affect the brain, heart, and blood vessels, as well as metabolic processes such as weight loss and fat reduction. 4. Total cholesterol level more than 239 mg/dL, triglycerides more than150 mg/dL, bad cholesterol LDL-C more than 159 mg/dL. 5. Are obese and are currently being treated with medication. 6. Drink more than 5 alcoholic beverages per day. 7. Smoke more than 10 cigarettes per day. 8. Currently using birth control pills 9. Are pregnant or plan to become pregnant during the research period. 10. Breastfeeding. 11. Currently participating in other projects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of Oxidative stress baseline and 7, 14 day Malondialdehyde (MDA) , 8-OHDG, 8-isoprostane, OxLD | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in mental health conditions baseline and 7, 14 day Questionnaire (GHQ) ,Changes in biochem-cardiovascular baseline and 7, 14 day glucose concentration (AUC), insulin, Homeostatic Model Assessment for Insulin Resistance, HOMA-IR) (lipid profiles, oxidized LDL),Changes in cardiovascular baseline and 7, 14 day BP, Blood flow, cerebral blood flow, Atherogenic index in plasma (AIP), VCAM1,Changes in Inflammatory markers baseline and 14 day Il-6, IL-10, IL-17, TNF-alpha, CRP),Changes in Immune markers baseline and 14 day CD4+, CD8+, CD28+ ,T cells mononuclear cells (PBMC),Changes in Polyphenolic compounds baseline and 14 day Polyphenolic compounds concentration in serum,Changes in neuromarkers baseline and 14 day Brain Derived Nerve Growth Factor (BDNF), serum amyloid-A, SAA , cortisol,Changes in homeostasis baseline and 14 day Nrf2, sirtuin1 ,Changes in probiotics in gut baseline and 14 day Lactobacillus spp , Bifidobacterium spp, Short chain fatty acid | — |
Countries
Thailand
Contacts
Public ContactJintanaporn Wattanathorn
Faculty of Medicine, Khon Kaen University
Outcome results
None listed