Central nervous system infection is a factor associated with an increase in perioperative mortality. Post-operative neurosurgical infection still highly prevalent and lethal syndrome. Nowadays, the Surviving Sepsis Campaign (SSC) has been developed as a guideline, but no study explores the clinical outcome. neurosurgical infection after craniotomy, mortality rate, surviving Sepsis Campaign, sepsis, Protocol
Conditions
Interventions
The Neurosurgical Sepsis protocol recommended one-hour bundles of sepsis care that consisted of obtaining blood lactate level, hemocultures before empirical antibiotics, and appropriate empirical anti
One hour bundle protocol,Usual care
Sponsors
Phramongkutklao Hospital Foundation
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: All consecutive neurosurgical patients with sepsis and septic shock admitted to the neurosurgical intensive care unit.
Exclusion criteria
Exclusion criteria: The patients that refused to study. The patients that had pre-existing systemic disease. The patients that were significantly limiting life expectancy. The patients that were transferred to tertiary care hospital. The patients that were intolerance to protocol. The patients that were pulmonary embolism. The patients that were congestive heart failure or acute myocardial infarction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day medians survival analysis before and after the sepsis and septic shock treatment care bundle was set up 28 day 28-day medians survival analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| differences in ICU length of stay, ventilator, vasopressor-free day, and factors associated with mortality 28 day Patient reported outcome using a review sepsis and septic shock data base | — |
Countries
Thailand
Contacts
Public ContactPANU BOONTOTERM
Phramongkutklao College of Medicine and Hospital
Outcome results
None listed