Overweight/obese men (BMI: 23-30 kg/m2) Overweight Obesity
Conditions
Interventions
High-fat meal plus aloe vera gel extract as a drink,High-fat meal plus aloe vera gel extract with 0.5 g acemannan as a drink,High-fat meal plus aloe vera gel extract with 1 g acemannan as a drink,-
Aloe vera gel extract,Acemannan (0.5 g),Acemannan (1 g),-
Sponsors
Chulalongkorn University
Eligibility
Sex/Gender
Male
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: - Age 20-40 years old men - BMI 23-30 kg/m2 - Fasting blood glucose < 100 mg/dl - Blood urea nitrogen (BUN) 8-24 mg/dL - Creatinine 0.84 - 1.21 mg/dL - Aspartate transaminase (AST) 8 - 48 U/L - Alanine transaminase (ALT) 7 - 55 U/L - Blood pressure < 120/80 mmHg - White blood cell count 3,500 - 10,500 cells/mcL - Healthy adult without underlying medical conditions and medicine taking - No smoker and alcohol users
Exclusion criteria
Exclusion criteria: - Chronic diseases such as diabetes mellitus, hypercholesterolemia, liver and kidney diseases etc. - Allergy to cow milk, wheat, gluten, butter, agar, bovine gelatin or aloe vera gel/acemannan - Using any dietary supplements or medications related to antioxidants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum triglyceride 0, 60, 120, 180, 300, 360 min Enzymetic colorimetric method,Antioxidant status 0, 30, 60, 90, 120, 180 min Colorimetric methods | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma glucose, serum insulin 0, 30, 60, 90, 120, 180 min Enzymetic colorimetric method, ELISA,Serum inflammatory cytokines 0, 360 min ELISA,Appitite sensation 0, 10, 30, 60, 90, 120, 180, 240, 300, 360 min Visual analogue scale (VAS) | — |
Countries
Thailand
Contacts
Public ContactProf. Sirichai Adisakwattana
Chulalongkorn Universiry
Outcome results
None listed