healthy infants gestational age less than 32 weeks and weighing less than 1800 grams Preterm, Human milk, Human milk fortifier, Protein, Growth
Conditions
Interventions
In the adjustable fortification group, protein of 0.5 g/100 ml was initially added to the standard fortified HM to achieve a target of 3.5-4 g/kg/day protein. Further protein adjustments were made the
s protein metabolism, which was determined by blood urea nitrogen (BUN) weekly,Standard fortification was performed by adding a fixed amount of fortifier to mother'
s own milk or donor human milk 25 ml+ HMF 1 sachet (24 kcal/oz) as per the manufacture'
s recommendation HMF [Mead Johnson nutritional].
adjustable fortification,standard fortification
Sponsors
The Perinatal Society of Thailand
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All Preterm infants with GA < 32 weeks and weight < 1800 grams, admitted in the neonatal unit of QSNICH
Exclusion criteria
Exclusion criteria: major congenital anomalies, chromosomal abnormalities, gastrointestinal abnormalities (gastroschisis, omphalocele, bowel obstruction), post major surgery, intrauterine infection, SGA or LGA
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| growth outcomes the study duration was 28 days or discharge which ever comes first. birth weight, length, head circumference | — |
Secondary
| Measure | Time frame |
|---|---|
| chemical parameters weekly serum blood urea nitrogen (BUN), creatinine, and albumin,clinical outcomes the study duration was 28 days or discharge which ever comes first. confirmed necrotizing enterocolitis , feeding intolerance, late-onset neonatal culture-proven sepsis and other, nosocomial infections, length of stay, extrauterine growth restriction | — |
Countries
Thailand
Contacts
Public Contactsareeporn Iamprasertkul
Queen Sirikit National Institute of Child Health
Outcome results
None listed