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Can intravenous lidocaine definitely attenuate propofol requirement and improve outcomes among colonoscopic patients under intravenous sedation?: A double-blinded, randomized controlled trial

Can intravenous lidocaine definitely attenuate propofol requirement and improve outcomes among colonoscopic patients under intravenous sedation?: A double-blinded, randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210517001
Enrollment
70
Registered
2021-05-17
Start date
2021-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The propofol-sparing effect of intravenous lidocaine in patients undergoing colonoscopy with bispectral index monitoring. bispectral index, colonoscopy, lidocaine, monitoring, propofol

Interventions

Lidocaine 1.5 mg/kg iv bolus then infusion 4 mg/kg/h,Normal saline bolus and infusion
Experimental Drug,Placebo Comparator No treatment

Sponsors

Phramongkutklao hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 20 to 80 years 2. American Society of Anesthesiologists physical status I-III

Exclusion criteria

Exclusion criteria: 1. Severe cardiovascular and pulmonary diseases 2. Liver or renal insufficiency 3. Mental disorders 4. language barrier 5. history of colectomy 6. history of being allergic to lidocaine

Design outcomes

Primary

MeasureTime frame
Total dosage of intravenous propofol At the end of the operation Milligram of propofol

Secondary

MeasureTime frame
a comparison of hemodynamic variations, episodes of oxygen desaturation, the duration of full consciousness and prompt response to the PACU, the sedative level , patient satisfaction, pain score Within 60 minutes in the recovery room Verbal numerical rating score (VNRS), blood pressure and oxygen saturation percent changes, patient satisfaction, BIS

Countries

Thailand

Contacts

Public ContactKrisana Nongnuang

Phramongkutkal hospitsl

krisana-anesth@hotmail.com66891530992

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026