Prophylactic cranial irradiation with hippocampal sparing technique in small cell lung cancer patients

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200725001

Enrollment

Registered

2020-07-25

Start date

2018-10-26

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who is diagnosed small cell lung cancer and fulfilled criterion for prophylactic cranial irradiation will be enrolled to this study hippocampal sparing&#44

Interventions

prophylactic cranial irradiation with hippocampal sparing technique in small cell lung cancer patients

No Intervention Radiation

prophylactic cranial irradiation

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.age 18 to 80 years old 2.ECOG 0-2 3.histopathological diagnosed small cell lung cancer 4.no evidence of brain metastasis on cranial-MRI 5.no progression of primary tumor and/or extra-cranial metastasis after complete standard treatment (chemotherapy and/or thoracic radiotherapy)

Exclusion criteria

Exclusion criteria: 1.history of previous cranial irradiation 2.evidence of leptomeningeal dissemination

Design outcomes

Primary

Measure	Time frame
Rate of hippocampal metastasis after cranial irradiation serial MRI and physical examination	—

Secondary

Measure	Time frame
cognitive function, 2-yr overall survival, rate of brain metastasis after cranial irradiation TMSE, serial MRI and physical examination	—

Countries

Thailand

Contacts

Public ContactBongkot Jia-Mahasap

Chiang Mai University

phung_nemo@hotmail.com053935450

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026