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Is The Only Buccal Infiltration Anesthesia with Lidocaine Enough for Extraction of Mandibular Anterior Incisors and Premolar Teeth?

Is The Only Buccal Infiltration Anesthesia with Lidocaine Enough for Extraction of Mandibular Anterior Incisors and Premolar Teeth? A Randomized, Prospective, Split-Mouth Designed Clinical Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200425003
Enrollment
Unknown
Registered
2020-04-25
Start date
2019-11-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Although infiltration anesthesia has been used successfully in mandibular anterior tooth extraction&#44

Interventions

Extraction with only buccal infiltration anesthesia on one side (n=66),Extraction with buccal and additional lingual infiltration anesthesia on the other side (n=66)
Active Comparator Procedure/Surgery,Experimental Procedure/Surgery

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: • age of 18 years or older, • patients with bilateral mandibular premolar or incisor teeth definitely requiring nonsurgical removal with local anesthesia, • patients with willingness to give informed consent and were cooperate with the study, • patients with American Society of Anesthesiology (ASA) physical status class I and II,

Exclusion criteria

Exclusion criteria: • ASA > II, • patients with any systemic diseases including uncontrolled hypertension, diabetes or malignancy or any medical conditions, • bleeding disorders, using antiplatelet or anticoagulant therapy; • using or previous chemotherapy, radiotherapy and bisphosphonate therapy, • any acute infection or local inflammation in the local exraction area; • local pathology (e.g., cyst or tumor) associated with the tooth to be extracted, • systemic viral, fungal or bacterial infections, • allergy to the lidocaine or the other drugs used in the surgical protocol, • using any anti-inflammatory, antidepressant or sedative medication in the last 12 hours as it may change the perception of pain, • pregnancy or lactation or using oral contraceptives; • consumption of alcohol or smoking were excluded from the study.

Design outcomes

Primary

MeasureTime frame
Injection pain after the local infiltration anesthesia immediately after injection Visual Analog Scale and Face Pain Scale

Secondary

MeasureTime frame
Extraction pain after removal of mandibular teeth immediately after extraction of the tooth Visual Analog Scale and Face Pain Scale

Contacts

Public ContactBilal Ege

Adıyaman University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery

miregein@gmail.com+90507 927 97 34

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026