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Efficacy of Preemptive Analgesia on Tourniquet and Post-Operative Pain Relief in Open Carpal Tunnel Release : A Prospective Randomized Control Trial

Efficacy of Preemptive Analgesia on Tourniquet and Post-Operative Pain Relief in Open Carpal Tunnel Release : A Prospective Randomized Control Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200317006
Enrollment
40
Registered
2020-03-17
Start date
2019-02-26
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who were diagnosed as carpal tunnel syndrome and underwent operated under local anaesthesia with 1% xylocaine injection at surgical site and used tourniquet at arm for hemostasis. Tourniquet pain&#44

Interventions

received 300 mg of gabapentin&#44
200 mg of celecoxib and 500 mg of acetaminophen&#44
two hours prior to surgery,Received 3 placebo&#44
two hours prior to surgery
Experimental Drug,Placebo Comparator Drug

Sponsors

H.R.H. Maha Chakri Sirindhorn Medical Center (MSMC)
Lead Sponsor
H.R.H. Maha Chakri Sirindhorn Medical Center (MSMC)
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age > 18 years old Patient who are diagnosed with CTS by clinical Patient who has indication for open carpal tunnel release

Exclusion criteria

Exclusion criteria: Patient who refused operative treatment Patient who has indication for opponenplasty Patient who has history of allergy to Gabapentin, NSAIDs, sulfonamide, paracetamol and corn flour Patient who has contraindications to using a tourniquet Patient who has history of GI bleeding Pregnancy or breast feeding women Patients who had received analgesics within 48 hours before surgery Patient who could not read or understand the consent form and data collection form

Design outcomes

Primary

MeasureTime frame
Tourniquet site pain Postoperatively VAS,Surgical site pain 6, 12, 24 hours postoperatively VAS

Secondary

MeasureTime frame
Acetaminophen consumption 24 hours postoperatively Number of acetaminophen (tablets)

Countries

Thailand

Contacts

Public ContactNaphakkhanith Dhanachanvisith

H.R.H. Maha Chakri Sirindhorn Medical Center (MSMC)

best_072@hotmail.com0897669602

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026