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Combined Oral Contraceptive Pills after Unilateral Salpingo-oophorectomy and Hysterectomy in Patients with Endometrioma: A Randomized Controlled Study

Combined Oral Contraceptive Pills after Unilateral Salpingo-oophorectomy and Hysterectomy in Patients with Endometrioma: A Randomized Controlled Study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190417002
Enrollment
Unknown
Registered
2019-04-17
Start date
2019-04-12
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriotic cyst Endometriosis&#44

Interventions

No treatment,combined estrogen&#45
progestin pill composed of ethinyl estradiol (0.02 mg/tab)& Desogestrel (0.15 mg/tab)
control,combined estrogen&#45

Sponsors

Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1) healthy women age 20-50 years 2) diagnose endometrioma size at least 3 cm in diameter and performed unilateral salpingo-oophorectomy and hysterectomy already 3) No history of oral hormone within 3 months and no treatment history of รับ depot-medroxyprogesterone acetate (DMPA) or GnRH agonist 9 months before surgery 4) no contraindication for Ethinyl estradiol และDesogestrel 5) no desire for a child

Exclusion criteria

Exclusion criteria: 1) liver cirrhosis, chronic renal disease, coagulopathy or has a disease not suitable for surgery 2) have a contraindication to Ethinyl estradiol or Desgestrel 3) cannot tolerate to abnormal uterine bleeding, side effect of progestin-only pills 4) deny participating to the study

Design outcomes

Primary

MeasureTime frame
Pain symptom 0, 3, 6, 12, 18 months visual analogue scale, verbal rating scale,Pain symptom 0, 3, 6, 12, 18 months visual analogue scale, verbal rating scale,recurrent endometriotic cyst 6, 12, 18 months number of cyst

Secondary

MeasureTime frame
Side effect 0, 3, 6, 12, 18 months Bleeding amount and pattern

Countries

Thailand

Contacts

Public ContactAreepan Sophonsritsuk

Ramathibodi Hospital

areepan.sop@mahidol.ac.th0809096531

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026