Adjuvant chemotherapy in the patients with stage II colon cancer that have MSI-H status and poor prognostic factors : to give or not to give?

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20180329003

Enrollment

200

Registered

2018-03-29

Start date

2018-03-23

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

To find out if the patients with stage II colon cancer that have MSI&#45

Interventions

Stage II colon cancer with poor prognostic factor with MSI&#45

H with adjuvant chemotherapy,Stage II colon cancer with poor prognostic factor with MSI&#45

H without adjuvant chemotherapy,Stage II colon cancer with poor prognostic factor with MSI&#45

L/MSS with adjuvant chemotherapy,Stage II colon cancer with poor prognostic factor with MSI&#45

L/MSS without adjuvant chemotherapy

Treatment,Treatment,Treatment,Treatment

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: -Patients with pathologically confirmed stage II colon cancer with poor prognostic factors -Age > 18 years -Available tissue specimen for MMR testing

Exclusion criteria

Exclusion criteria: -Not available tissue specimen for MMR testing

Design outcomes

Primary

Measure	Time frame
Disease free survival, overall survival 5 years after the operation Kaplan meier method	—

Secondary

Measure	Time frame
complication from treatment 6 months after the adjuvant chemotherapy percentage	—

Countries

Thailand

Contacts

Public ContactPrapon Kajanasilp

Colorectal division, Chulalongkorn hospital

pon5822@gmail.com0814939554

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Adjuvant chemotherapy in the patients with stage II colon cancer that have MSI&#45;H status and poor prognostic factors : to give or not to give?