depression curcumin depression inflammation
Conditions
Interventions
Curcumin ( add on antidepressant),Placebo ( add on antidepressant)
Sponsors
Agricultural Research Developmental Agency ( Public Organization)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Montgomery Asberg depressive rating scale (MADRS) more than 20 scores 2. Normal CBC. EKG,BUN/Cr, Liver function test 3. Accept to participate in the study
Exclusion criteria
Exclusion criteria: 1.Pregnant women ( Negative pregnancy test) 2. No previous history of curcumin allergy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| depressive scores 16 weeks Questionnaires,anxiety scores, quality of life scores 16 weeks Questionnaires | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxidative stress biomarkers baseline and after 12 week of treatment blood specimen analysis | — |
Countries
Thailand
Contacts
Public ContactBuranee Kanchanatawan
King Chulalongkorn Memorial Hospital
Outcome results
None listed