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Randomized Controlled Trial comparing Lumbar Epidural Anesthesia and Controlled Group in Patients undergoing Laparoscopic Colorectal Surgery in the Aspects of Short-term Surgical Recovery Outcomes, Stress Response and the Incidence of Acute Kidney Injury

Randomized Controlled Trial comparing Lumbar Epidural Anesthesia and Controlled Group in Patients undergoing Laparoscopic Colorectal Surgery in the Aspects of Short-term Surgical Recovery Outcomes, Stress Response and the Incidence of Ac

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20150708002
Enrollment
50
Registered
2015-07-08
Start date
2015-09-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient undergoing laparoscopic colorectal surgery laparoscopic colorectal surgery

Interventions

no intervention,An epidural catheter will be inserted before general anesthesia in any of the first to forth lumbar interspaces with a depth of 3&#45
4 centimeters of catheter&#45
in&#45
space. A loading dose of 10 mL of 0.25% Bupivacaine will be administered via epidural catheter and maintained with continuous infusion of 0.25% Bupivacaine at rate 5 mL/Hr throughout the operation. Af
the patient in the epidural group will get another two more consecutive intermittent doses of 4&#45
mg epidural morphine in 8&#45
ml normal saline at the 18 th and 36 th postoperative hour&#44
respectively
No Intervention No treatment,Experimental Procedure/Surgery
Control,ContinuouscLumbar Epidural Anesthesia

Sponsors

Ratchadapiseksompotch Fund
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: a. patients scheduled for elective laparoscopic colon resection b. age between 18-80 years c. American Society of anesthesiologists physical status I-III d. Elective surgery

Exclusion criteria

Exclusion criteria: a. Conversion to open surgery b. Medical contraindications to Epidural Anesthesia c. Chronic use of analgesic drugs

Design outcomes

Primary

MeasureTime frame
Time to first tolerance of soft diet daily interview—

Secondary

MeasureTime frame
Serum cortisol level baseline, intraoperative, postoperative day 1 Laboratory test,Visual Analog Pain Score twice a day until postoperative day 3 Interview,Opioid consumption daily Record from IV-PCA,Urine NGAL level baseline, postoperative day 1 Laboratory test,Complication daily Interview—

Countries

Thailand

Contacts

Public ContactBenjamas Kiatkasemsan

Chulalongkorn University

book_let@hotmail.com+6689-668-5205

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026