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Evaluation of the relationship between salt intake and blood pressure in different amounts of salt consumed

A double-blind, randomized clinical trial to evaluate the dose-response relationship between salt intake and blood pressure at different levels of salt intake

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7yjwpf
Enrollment
Unknown
Registered
2017-01-17
Start date
2013-03-20
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension Sodium in the diet

Interventions

The total calculated sample was composed by at least 75 individuals, 25 individuals for each group (normotensive, borderline and hypertensive). Those between 20 and 60 years old of both sexes were inc
using more than two antihypertensive drugs or secondary hypertension
diabetics (type I and II)
with history of atherosclerotic disease (acute myocardial infarction, stroke in the last 6 months)
individuals in need of some special diet (religious, dietary control, syndromes) and those who did not perform at least 4 main meals (lunch and / or dinner) per week, prepared at home. Study Procedur
In this phase, questionnaires were used on quality of life and risk factors for cardiovascular diseases, anthropometric and blood pressure measurements, food habits and salt consumption questionnaires
Behavioural

Sponsors

Universidade Federal de Goiás
Lead Sponsor
Liga de Hipertensão Arterial do Hospital das Clínicas da Universidade Federal de Goiás
Collaborator

Eligibility

Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Workers of Campus I of the Federal University of Goiás; Age between 20 and 60 years; Of both sexes.

Exclusion criteria

Exclusion criteria: Blood pressure greater than 160mmHg of systolic and 100mmHg of diastolic independent of the use of hypotensors; Use of more than two antihypertensive drugs or secondary hypertension; Type I and II diabetics; History of atherosclerotic disease; Need for special diet for any reason whether religious, dietary control or syndromes; Do not carry out at least 4 main meals per week, prepared at home, whether lunch or dinner.

Design outcomes

Primary

MeasureTime frame
Reduction of systolic blood pressure and diastolic blood pressure (mmHg) in the three groups evaluated (hypertensive, borderline and normotensive), verified by casual blood pressure measurement (in the office), by comparing the means of the casual measurements to each After the reduction of the use of addition salt delivered by the study every 4 weeks in three levels (6g, 5g and 4g of salt / day).;There was no significant reduction in systolic and diastolic blood pressure between normotensive and borderline subjects from baseline to the end of the study, and the hypertensive group significantly reduced systolic and diastolic blood pressure from the first to the last visit, as measured by the casual measure of Blood pressure (in the office), from a comparison of the casual measurements at each visit. The hypertensive group reduced 7.2 mmHg at systolic pressure and 4.3 mmHg at diastolic pressure (p <0.005), considering the initial and final values.

Secondary

MeasureTime frame
Secondary outcomes are not expected

Countries

Brazil

Contacts

Public ContactAna Luiza Sousa

Liga de Hipertensão Arterial do Hospital das Clínicas da Universidade Federal de Goiás

demmilima@gmail.com+55(62)981595010

Outcome results

None listed

Source: REBEC (via WHO ICTRP)