Effect of creatine supplementation associated with a program of weight training on muscle mass, strength and physical performance in elderly with reduced muscle mass

Effect of creatine supplementation associated with resistance training on muscle mass, strength and physical performance in Sarcopenic elderly

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

REBEC

Registry ID

RBR-7r7t52

Enrollment

Unknown

Registered

2015-03-02

Start date

2014-07-04

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia, elderly.

Interventions

Experimental group: 14 subjects supplemented with 5 grams creatine monohydrate per day after lunch, when there is no resistance training, or 5 grams of creatine plus 100 grams of maltodextrin immediat

Dietary supplement

Other

I02.233.543

D02.078.370.280

D26.660

Eligibility

Age

60 Years to 80 Years

Inclusion criteria

Inclusion criteria: Have between 60 and 80 years of age; Be diagnosed with sarcopenia.

Exclusion criteria

Exclusion criteria: Be vegetarian; Take any ergogenic aid in the last 6 months prior to study initiation; Ingest any medication that can affect muscle growth or the ability to train intensely during the study (statins, muscle relaxants, anti-inflammatory); Be involved in restricting food programs; Be involved in physical training programs; Received contrast or performed radioactive procedure last year; Have any kidney disease, liver disease and heart disease.

Design outcomes

Primary

Measure	Time frame
Increase body muscle mass by dual energy x-ray absorptiometry, from the variation of at least 10% in the pre and post intervention measurements.;Strength increase assessed by 10RM test performed in bench and leg press exercises, from the variation of at least 50% in the pre and post intervention measurements.;Increased muscle mass from the observation of variation of 4.7% in the pre and post intervention measurements and superior gain when compared to placebo group.;Significant increase, on the measurements of pre and post intervention, from the variation of 78.2% and 89.7% 4.7% performed in bench press and leg press exercises.	—

Measure

Time frame

Increase body muscle mass by dual energy x-ray absorptiometry, from the variation of at least 10% in the pre and post intervention measurements.;Strength increase assessed by 10RM test performed in bench and leg press exercises, from the variation of at least 50% in the pre and post intervention measurements.;Increased muscle mass from the observation of variation of 4.7% in the pre and post intervention measurements and superior gain when compared to placebo group.;Significant increase, on the measurements of pre and post intervention, from the variation of 78.2% and 89.7% 4.7% performed in bench press and leg press exercises.

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Secondary

Measure	Time frame
Increase bone mineral density by dual energy x-ray absorptiometry, from the variation of at least 5% in the pre and post intervention measurements.;Increase bone mineral content by dual energy x-ray absorptiometry, from the variation of at least 5% in the pre and post intervention measurements.;Bone mineral density did not change in pre and post intervention and between groups.;Bone mineral content did not change pre and post intervention and between groups.	—

Measure

Time frame

Increase bone mineral density by dual energy x-ray absorptiometry, from the variation of at least 5% in the pre and post intervention measurements.;Increase bone mineral content by dual energy x-ray absorptiometry, from the variation of at least 5% in the pre and post intervention measurements.;Bone mineral density did not change in pre and post intervention and between groups.;Bone mineral content did not change pre and post intervention and between groups.

—

Countries

Brazil

Contacts

Public ContactJoão Mota

Faculdade de Nutrição da Universidade Federal de Goiás

jfemota@gmail.com+55(62)32096270

Outcome results

None listed

Source: REBEC (via WHO ICTRP)