Embolism and thrombosis of unspecified vein
Conditions
Interventions
This will be a prospective interventionist study, whose intervention will be the use of a low-fat diet in patients with historical thrombotic Antiphospholipid Syndrome and dyslipidemia. The primary ev
Behavioural
Sponsors
Centro de Hematologia e Hemoterapia de Campinas - Hemocentro
Centro de Hematologia e Hemoterapia de Campinas - Hemocentro
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Subjects were selected from patients diagnosed with thrombosis associated with primary APS, followed at the Hemostasis outpatient clinic of the State University of Campinas (UNICAMP). All patients with primary APS and dyslipidemia who had a history of arterial or venous thrombosis of both sexes, aged over 18 years and diagnosed with dyslipidemia were included. The criteria for the diagnosis of dyslipidemia were: LDL-c above 100mg / dL, HDL-c below 40mg / dL (men) and 50mg / dL (women), TG above 200mg / dL, TC above 190mg / dL , non-HDL cholesterol above 130mg / dL or still on low-fat medications. LDL-c values above 100mg / dL were considered because they were patients with a history of thrombotic disease.
Exclusion criteria
Exclusion criteria: Patients diagnosed with systemic autoimmune disease or neoplasia were excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected Outcome 1: Evaluate whether the low-fat diet is associated with a decrease in Total Cholesterol and non-HDL cholesterol levels, after 6 months of nutritional monitoring with indication of the low-fat diet, by laboratory analysis;;Outcome found 1: Total cholesterol levels decreased significantly after nutritional intervention through the low-fat diet, as did non-HDL cholesterol after 6 months of follow-up.;Expected Outcome 2: Comparison of the mean difference after 6 months of nutritional follow-up through the indication of a low-fat diet, by laboratory analysis, a reduction in LDL-c levels and an increase in HDL-c.;Outcome found 2: There were no significant changes in LDL-c and HDL-c levels in this study | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome in this study | — |
Countries
Brazil
Contacts
Public ContactFernanda;Thays de Andrade Orsi;Rodrigues
Centro de Hematologia e Hemoterapia de Campinas - Hemocentro;Centro de Hematologia e Hemoterapia de Campinas - Hemocentro
Outcome results
None listed