Obesity
Conditions
Interventions
Twenty normal-weight and twenty overweight or obese women (20-40 years old) received two different meals, rich in saturated fatty acid (26% of energy intake), including orange juice (500 mL)- test me
Other
Sponsors
Universidade Federal de Viçosa
Universidade Federal de Viçosa
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Women, age between 20-40 years-old, normal-weight (BMI: 18,5-24,9 kg/m2) or overweight/Obesity (BMI: 25,0-35,0 kg/m2), no smokers
Exclusion criteria
Exclusion criteria: Pregnancy or lactiontion or menopause. Infections or inflammation in the experiment days; Inflammatory, heart, liver, renal, gastrointestinal and respiratory diseases; Hormonal treatment or prescribed drug that affect glucose metabolism; Alcoholic or drug dependence; Smoking; Recent follow-up of diets designed to weight loss or unstable weight in the last three months (higher than 5% usual weight); To be athlete
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The consumption of orange juice will prevent the postprandial inflammatory response (C-reactive protein, C3 complement and cytokines concentrations as well as gene expression of gene inflammatory promoters in peripheral blood mononcluear cells - PBMC) to saturated fatty acid intake, at posprandial times (2, 3 or 5 h), compared to control meal (water intake);The inflammatory posprandial response (2, 3 or 5 h) to saturated fatty acid intake will be increased among overweight women, at posprandial times, compared to normal-weight women;The improvement in the inflammatory posprandial response (2, 3 or 5 h) to orange juice consumption will be lower in overweight women, compared to normal-weight women | — |
Secondary
| Measure | Time frame |
|---|---|
| The metabolic response (serum glucose, insulin, triglycerides, uric acid, total cholesterol, HDL-c and LDL-c concentrations) to saturated fatty acid intake will be different between normal-weight and obese women at postprandial time | — |
Countries
Brazil
Contacts
Public ContactHelen Hermana Hermsdorff
Universidade Federal de Viçosa
Outcome results
None listed