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The effect of a substance in Green tea in the decrease of compounds formed in the food preparation process that affect human health

Effect of Epigallocatechin-3-Gallate on serum concentrations of Carboxymethyl-Lysine in Inflammation, Insulin Resistance and Endothelial dysfunction caused by acute ingestion of a meal high in advanced glycation end products

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2b8p4n
Enrollment
Unknown
Registered
2018-08-22
Start date
2017-05-20
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention of the ills caused by the ingestion of fat and advanced glycation end products (AGEs) in healthy women.

Interventions

The study was a randomized, double-blind, placebo-controlled, crossover clinical trial with 16 ( all the women participate in both groups - placebo and intervention) healthy young women, 18 to 25 year
Dietary supplement

Sponsors

Faculdade de Nutrição da Universidade Federal de Goiás
Lead Sponsor
Faculdade de Nutrição da Universidade Federal de Goiás
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 25 Years

Inclusion criteria

Inclusion criteria: Female; healthy; eutrophic (BMI between 18.5 kg / m2 and 24.9 kg / m2) and age between 18 and 25 years.

Exclusion criteria

Exclusion criteria: Cardiovascular, pulmonary or metabolic diseases; use of anti-inflammatory medications and corticosteroids; food restrictions related to the meal used in the study (potato chips, bacon and Parmesan cheese); pregnant and / or lactating; smoker.

Design outcomes

Primary

MeasureTime frame
The expected outcome for the present study is 10% reduction in advanced glycation end products (AGE), measured by serum carboxymethyl lysine, and triglycerides concentrations 120 minutes after epigallocatechin-3-gallate administration and AGE-rich meal intake.

Secondary

MeasureTime frame
An improvement in insulin resistance (5%) is expected after (120 min) the epigallocatechin-3-gallate administration and AGE-rich meal intake.;A reduction in insulin resistance (5%) is expected after (120 min) the epigallocatechin-3-gallate administration and AGE-rich meal intake.

Countries

Brazil

Contacts

Public ContactJoão Mota

Faculdade de Nutrição da Universidade Federal de Goiás

jfemota@gmail.com+55-062-32096270

Outcome results

None listed

Source: REBEC (via WHO ICTRP)