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Effectiveness of Tranexamic acid in reducing blood loss during myomectomy in federal Medical Centre, Owerri: A randomised controlled trial

Effectiveness of Tranexamic acid in reducing blood loss during myomectomy in federal Medical Centre, Owerri: A randomised controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202001691971779
Enrollment
60
Registered
2020-01-14
Start date
2019-11-14
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine fibroid

Interventions

Intravenous Tranexamic acid

Sponsors

Onwukwe Emeka
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1) Consenting women scheduled to have abdominal (laparotomy and ) myomectomy 2) uterine size of 16 weeks and above with multiple uterine fibroids

Exclusion criteria

Exclusion criteria: 1) women with known allergy to Tranexamic acid 2) women with current and / or previous thromboembolic disease 3) women with bleeding disorders 4) women taking combine oral contraceptive pills 5) women who had received Gonadotrophin Releasing hormone analogue within three month of the proposed surgery 6) women who are receiving Tranexamic acid for menorrhagia within one month of surgery

Design outcomes

Primary

MeasureTime frame
Estimated intraoperative blood loss

Secondary

MeasureTime frame
Packed cell volume postoperative;Number of participants requiring blood transfusion;The number of units of whole blood transfused;Duration of sugery

Countries

Nigeria

Contacts

Public ContactOnyedikachi Ezirim

Resident Doctor

teddyezirim@yahoo.com+2347038715726

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026