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ARTEMETHER-LUMEFANTRINE VERSUS ARTESUNATE- AMODIAQUINE IN PREGNANT WOMEN

Artemether-lumefantrine versus Artesunate-amodiaquine for treatment of uncomplicated plasmodium falciparum malaria in pregnancy; A randomized control trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201310000484185
Enrollment
150
Registered
2013-01-15
Start date
2013-01-17
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria Pregnancy and Childbirth

Interventions

Sponsors

Ukah Chukwuemeka Marcel
Lead Sponsor
Obafemi Awolowo university teaching hospitals complex
Collaborator

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1.Symptoms of malaria such as fever (T 37.5oc), headaches, body pains within 24 hours before presentation. 2.Microscopically-confirmed P. falciparum malaria with parasitaemia of at least one plus (1-10 parasites/100 thick film field). 3.Consent to participate in the study 4.Willingness/ability to comply with follow-up schedule

Exclusion criteria

Exclusion criteria: 1.Severe malaria or danger signs of severe malaria (e.g. loss of consciousness, convulsions, anuria) 2.Women in the first trimester of pregnancy 3.Use of any anti-malarial drug other than sulphadoxine pyrimethamine less than 7 days before presentation 4.Other concurrent pregnancy related diseases e.g. urinary tract infections. 5.History of reaction to any of the drugs. 6.Patients not tolerating orally.

Design outcomes

Primary

MeasureTime frame
1.To compare the efficacy of the artemether/lumefantrine and artesunate amodiaquine fixed dose combinations in pregnant women with acute uncomplicated falciparum malaria

Secondary

MeasureTime frame
To assess the pregnancy outcome in these women

Countries

Nigeria

Contacts

Public ContactMarcel Ukah
panyvinous@yahoo.com+2347030497456

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Mar 4, 2026