Malaria Pregnancy and Childbirth
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Symptoms of malaria such as fever (T 37.5oc), headaches, body pains within 24 hours before presentation. 2.Microscopically-confirmed P. falciparum malaria with parasitaemia of at least one plus (1-10 parasites/100 thick film field). 3.Consent to participate in the study 4.Willingness/ability to comply with follow-up schedule
Exclusion criteria
Exclusion criteria: 1.Severe malaria or danger signs of severe malaria (e.g. loss of consciousness, convulsions, anuria) 2.Women in the first trimester of pregnancy 3.Use of any anti-malarial drug other than sulphadoxine pyrimethamine less than 7 days before presentation 4.Other concurrent pregnancy related diseases e.g. urinary tract infections. 5.History of reaction to any of the drugs. 6.Patients not tolerating orally.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To compare the efficacy of the artemether/lumefantrine and artesunate amodiaquine fixed dose combinations in pregnant women with acute uncomplicated falciparum malaria | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the pregnancy outcome in these women | — |
Countries
Nigeria