Neuroblastoma, Neuroblastoma (NB), Neuroblastoma (NBL), Neuroblastoma (Measurable Disease), Neuroblastoma Recurrent, Neuroblastoma in Children, Neuroblastoma. CNS
Conditions
Keywords
FMT, fecal transplant, fecal microbiota transplant, microbiome, dysbiosis
Brief summary
This study uses fecal microbiota transplant (FMT) to correct gut microbiome dysbiosis prior to and during standard-of-care neuroblastoma treatment
Detailed description
Patients with neurobastoma and concurrent dysbiosis showing a bifidobacteria-bacteroides gap will undergo fecal microbiota transplant as an adjunctive to standard-of-care oncology treatment.
Interventions
BIOLOGICALFecal Microbial Transplantation
This study will utilize donor stool from an infant
Sponsors
Microbiome Research Foundation
ProgenaBiome
Eligibility
Sex/Gender
ALL
Age
5 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* willingness of parent/guardian to sign ICF * diagnosis of neuroblastoma * dysbiosis of the gut microbiome
Exclusion criteria
* parent/guardian unwilling to sign ICF * dysbiosis does not show a bifidobaceteria-bacteroides gap * severely abnormal screening lab values
Countries
United States
Outcome results
None listed