Fecal Microbial Transplantation

BIOLOGICAL20 trials

Sponsors

Beth Israel Deaconess Medical Center, University of California, Irvine, Stony Brook University, London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's, Soroka University Medical Center

Conditions

Alcoholic HepatitisAtopic DermatitisCholangitis AcuteClostridium Difficile InfectionContinuous Glucose MonitoringCrohn DiseaseCrohn's DiseaseCrohns Disease

Early Phase 1

Fecal Microbial Transplantation in Patients With Crohn's Disease

CompletedNCT03267238

Stony Brook UniversityCrohn Disease

Start: 2017-06-16End: 2022-02-15Updated: 2022-02-21

Fecal Microbial Transplantation for C. Difficile and/or Ulcerative Colitis or Indeterminate Colitis

CompletedNCT03268213

Stony Brook UniversityClostridium Difficile Infection, Indeterminate Colitis, Ulcerative Colitis

Start: 2013-11-30End: 2022-02-15Updated: 2022-02-22

Efficacy of Fecal Microbial Transplantation Treatment in Adults With Atopic Dermatitis

CompletedNCT04613037

Tel-Aviv Sourasky Medical CenterAtopic Dermatitis

Start: 2017-11-01End: 2019-07-30Updated: 2020-11-03

Phase 1

Impact of Fecal Biotherapy (FBT) on Microbial Diversity in Patients With Moderate to Severe Inflammatory Bowel Disease

CompletedNCT01847170

Beth Israel Deaconess Medical CenterCrohn's Disease

Start: 2013-05-31End: 2016-11-30Updated: 2017-03-03

Fecal Microbial Transplantation in Combination With Immunotherapy in Melanoma Patients (MIMic)

Active, not recruitingNCT03772899

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sMelanoma

Start: 2019-03-27End: 2026-08-31Target: 20Updated: 2025-03-28

Phase 2

Fecal Microbiota Transplantation As a Potential Treatment for Parkinson's Disease

CompletedNCT03876327

Soroka University Medical CenterParkinson Disease

Start: 2015-08-19End: 2020-06-30Updated: 2020-08-05

Fecal Microbial Transplantation for Ileal Pouch Anal Anastomosis Patients

Tel-Aviv Sourasky Medical CenterIleal Pouch Anal Anastomosis

Start: 2018-07-05End: 2024-12-31Target: 40Updated: 2020-04-07

Fecal Microbiota Transplant vs Standard Treatment for Recurrent Non-Obstructive Cholangitis

Not yet recruitingNCT07509346

Puerta de Hierro University HospitalCholangitis Acute, Recurrence

Start: 2026-06-01End: 2029-12-31Target: 44Updated: 2026-04-03

Phase 3

Efficacy of Fecal Microbial Transplantation Treatment in Adults With Atopic Dermatitis

Tel-Aviv Sourasky Medical CenterAtopic Dermatitis

Start: 2020-10-15End: 2024-06-01Target: 50Updated: 2022-07-22

Fecal Microbial Transplantation in Severe Alcoholic Hepatitis

F.D. Roosevelt Teaching Hospital with Policlinic Banska BystricaAlcoholic Hepatitis

Start: 2018-04-01End: 2022-12-30Target: 50Updated: 2022-08-03

Unknown Phase

Fecal Microbiota Transplant for Recurrent Clostridium Difficile Infection

CompletedNCT02326636

University of California, IrvineClostridium Difficile Infection

Start: 2014-04-30End: 2018-10-26Updated: 2023-08-21

Fecal Microbial Transplantation and Vedolizumab Treatment of Crohn's Disease

Tel-Aviv Sourasky Medical CenterCrohn Disease, Microbial Substitution

Start: 2018-07-03End: 2023-01-31Target: 80Updated: 2020-04-01

Efficacy and Safety of Fecal Microbiota Transplantation in Patients with Irritable Bowel Syndrome

Active, not recruitingNCT06697119

Seoul National University HospitalIrritable Bowel Disease

Start: 2023-03-09End: 2027-04-25Updated: 2024-11-20

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Crohn Disease on Advanced Therapies

RecruitingNCT06890637

All India Institute of Medical SciencesCrohns Disease

Start: 2025-03-15End: 2028-03-15Target: 168Updated: 2025-04-04

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Crohn Disease

RecruitingNCT06890650

All India Institute of Medical SciencesCrohn Disease

Start: 2025-03-15End: 2028-03-15Target: 168Updated: 2025-04-04

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Ulcerative Colitis

RecruitingNCT06895252

All India Institute of Medical SciencesUlcerative Colitis (UC)

Start: 2025-03-15End: 2028-03-15Target: 220Updated: 2025-04-04

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Ulcerative Colitis on Advanced Therapies

RecruitingNCT06906445

All India Institute of Medical SciencesUlcerative Colitis

Start: 2025-03-15End: 2028-03-15Target: 220Updated: 2025-04-02

Fecal Microbiota Transplantation Among Adult Patients With Hematological Malignancies

Enrolling by invitationNCT07172191

Del-Pest Central Hospital - National Institute of Hematology and Infectious DiseasesMalignant Hematologic Neoplasm

Start: 2025-10-01End: 2030-12-31Target: 100Updated: 2025-09-15

Fecal Microbiota Transplant for Neuroblastoma in a Single Patient

ProgenaBiomeNeuroblastoma, Neuroblastoma. CNS, Neuroblastoma in Children +4

Updated: 2025-11-03

Fecal Microbiota Transplantation Intervention on Microbiota Composition and Insulin Sensitivity in Diabetes

RecruitingNCT07375797

Central Jutland Regional HospitalContinuous Glucose Monitoring, Diabetes Mellitus Type 2, Fecal Microbiota Transplantation (FMT) +1

Start: 2026-02-05End: 2026-09-01Target: 16Updated: 2026-02-19

Related Papers

Improved survival in advanced melanoma patients treated with fecal microbiota transplantation using healthy donor stool in combination with anti-PD1: final results of the MIMic phase 1 trial

Journal for ImmunoTherapy of Cancer2025-08-018 citations

3PM-guided innovation in treatments of severe alcohol-associated hepatitis utilizing fecal microbiota transplantation

The EPMA Journal2024-10-313 citations

Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity

Cancer Discovery2024-04-0353 citations

Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial.

2023-07-06313 citations

614 Microbiome modification with fecal microbiota transplant from healthy donors before anti-PD1 therapy reduces primary resistance to immunotherapy in advanced and metastatic melanoma patients

Regular and Young Investigator Award Abstracts2022-11-013 citations

Fecal microbiota transplantation followed by anti–PD-1 treatment in patients with advanced melanoma.

Journal of Clinical Oncology2022-06-0111 citations

Metagenomic and Bile Acid Metabolomic Analysis of Fecal Microbiota Transplantation for Recurrent Clostridiodes Difficile and/or Inflammatory Bowel Diseases

Medical Research Archives2022-01-0111 citations

Fecal microbiota transplant as a potential treatment for Parkinson's disease - A case series.

2021-06-3088 citations

P864 Combination of fecal microbiota transplantation from healthy donors with anti-PD1 immunotherapy in treatment-naïve advanced or metastatic melanoma patients

Poster presentations2020-04-0112 citations