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Gamma Knife Radiosurgery on Tectal Plate Gliomas

Impact of Gamma Knife Radiosurgery on Tectal Plate Gliomas

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07015710
Enrollment
60
Registered
2025-06-11
Start date
2021-01-01
Completion date
2024-12-01
Last updated
2025-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gamma Knife Radiosurgery, Tectal Plate Gliomas

Brief summary

This study aimed to assess the impact of gamma knife radiosurgery on tectal plate gliomas (TPGs).

Detailed description

Tectal plate gliomas (TPGs) represent a subset of brainstem gliomas that are predominantly slow-growing, low-grade tumors and rarely produce neurological deficits. Viable options include biopsy and monitoring with serial neuroimaging, surgical resection, radiotherapy (either early following surgery or late on evidence of disease progression), chemotherapy, and stereotactic radiosurgery (SRS). SRS using Gamma Knife radiosurgery (GKRS) has been identified in small case series as a safe and promising approach for managing TPGs that necessitate intervention beyond mere observation.

Interventions

Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).

Sponsors

Al-Azhar University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
5 Years to 55 Years
Healthy volunteers
No

Inclusion criteria

* Age from 5 to 55 years. * Both sexes. * Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).

Exclusion criteria

* High-grade glioma. * Tumor extension beyond the tectal region.

Design outcomes

Primary

MeasureTime frameDescription
Incidence of responseOne year post-procedureIncidence of response was recorded.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026