Gut Microbiome
Conditions
Brief summary
The objective of the proposed research is to determine the effects of fresh mango consumption on gut microbiome, and its relationship with skin health, sexual and mental health in relatively healthy adults.
Interventions
OTHERLow fat cookies
To determine the effects of low fat cookie consumption on physiological indicators of sexual, mental, skin, and gut health
OTHERMango
To determine the effects of mango consumption on physiological indicators of sexual, mental, skin, and gut health
Sponsors
San Diego State University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Generally healthy subjects * BMI 20-40 kg/m2
Exclusion criteria
* Smoker * Pregnant woman * Required antibiotics use * Required dietary supplement use * Required medication of metabolic disorders, mental health and sexual health * Allergy to mango or wheat
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of sexual health questionnaire scores | Baseline and week 4 | Change of sexual health questionnaire scores will be determined to examine effects of mango consumption vs low-fat cookies. |
| Change of depression questionnaire scores | Baseline and week 4 | Change of depression questionnaire scores will be determined to examine effects of mango consumption vs low-fat cookies. |
| Change of skin hydration scores | Baseline, 1 min post application and week 4consumption | Change of skin hydration scores will be determined to examine effects of mango consumption vs low-fat cookies |
| Change of microbiome diversity | Baseline and week 4 | Change of microbiome diversity will be determined to examine effects of mango consumption vs low-fat cookies. |
Countries
United States
Outcome results
None listed