Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Conditions
Keywords
breast cancer, radiotherapy
Brief summary
The main goal of the trial was to analyse the value of radiotherapy after breast conserving surgery for patients with breast cancer, and to find groups of patients where the treatment could be omitted.
Detailed description
The trial recruited patients between 1991-1996, and the primary outcome in terms of recurrences has been updated through the years since then. Tumour material has been collected in order to study prognostic and predictive factors for breast cancer patients that are treated today. Late side effects of the treatment are studied.
Interventions
RADIATIONpostoperative radiotherapy
50 Gy in 25 fractions
Sponsors
Region Skane
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
No minimum to 75 Years
Healthy volunteers
No
Inclusion criteria
* female * not over the age of 75 years * operated because of stage 1-2 invasive adenocarcinoma of the breast * radical excision of the tumour
Exclusion criteria
* earlier cancer except cancer in situ of the cervix or skin * distant metastases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Loco-regional recurrence | 35 years | Recurrence in the breast or regional lymph nodes |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| survival | 35 years | Does radiotherapy have an impact on survival? |
| Secondary malignancies | 35 years | Does radiotherapy have an impact on secondandary malignancies? |
Countries
Sweden
Outcome results
None listed