Postoperative Radiotherapy

RADIATION19 trials

Sponsors

Chinese Academy of Medical Sciences, Lisette Nixon, Guangxi Medical University, Zhongnan Hospital, Bielefeld University

Conditions

Adenoid Cystic CarcinomaBrain MetastasesBreast AdenocarcinomaBreast CancerBreast Cancer Early Stage Breast Cancer (Stage 1-3)Breast CarcinomaBreast NeoplasmsCancer

Phase 2

Adjuvant IMRT With Concommitant Raltitrexed Chemotherapy for Locally Advanced Gastric Cancer After D0/D1 Radical Resection

Zhongnan HospitalGastric Cancer

Start: 2017-01-31End: 2019-12-31Target: 48Updated: 2018-01-05

Concurrent Immunotherapy With Postoperative Radiotherapy in Intermediate/High Risk HNSCC Patients Unfit for Cisplatin: The IMPORT Study (IMPORT)

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityHead and Neck Squamous Cell Carcinoma

Start: 2020-08-10End: 2024-08-09Target: 316Updated: 2021-04-15

Postoperative Radiotherapy With Nimotuzumab ± Benmelstobart in Intermediate-Risk Head and Neck Squamous Cell Carcinoma

Not yet recruitingNCT07535567

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityHead and Neck Squamous Cell Carcinoma

Start: 2026-05-05End: 2028-12-31Target: 386Updated: 2026-04-30

Efficacy and Safety of Postoperative Concurrent Chemoradiotherapy for Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma: A Multicenter Prospective Phase II Study

RecruitingNCT07636824

Cancer Institute and Hospital, Chinese Academy of Medical SciencesExtrahepatic Cholangiocarcinoma and Gallbladder Carcinoma

Start: 2026-06-16End: 2029-05-30Target: 92Updated: 2026-06-24

Intensified Adjuvant Therapy for High-Risk Newly Diagnosed Glioblastoma With Subtotal Resection or Short-Term Progression

RecruitingNCT07670026

Second Affiliated Hospital, School of Medicine, Zhejiang UniversityGlioblastoma

Start: 2025-12-01End: 2027-12-01Target: 31Updated: 2026-06-25

Phase 3

Post-operative Adjuvant Treatment for HPV-positive Tumours (PATHOS)

Active, not recruitingNCT02215265

Lisette NixonHuman Papillomavirus (HPV)-Positive Oropharyngeal Cancer

Start: 2015-10-31End: 2028-04-30Target: 1269Updated: 2025-02-19

NeoRad Breast Cancer Study

RecruitingNCT04261244

Bielefeld UniversityBreast Cancer

Start: 2024-02-01End: 2034-03-31Target: 1826Updated: 2025-05-07

Unknown Phase

Study of Postoperative 3D-CRT/IMRT in Hepatocellular Carcinoma

CompletedNCT01456156

Chinese Academy of Medical SciencesHepatocellular Cancer

Start: 2008-01-31End: 2017-01-31Updated: 2017-07-05

Radiotherapy in Hepatocellular Carcinomas After Hepatectomy With Narrow Margin (<1 cm) and / or Microvascular Invasion

Guangxi Medical UniversityHepatoCellular Carcinoma

Start: 2017-11-01End: 2022-11-01Target: 620Updated: 2018-07-10

Comparison Between IORT and Postoperative Radiotherapy in Breast Conserving Surgery

TerminatedNCT04789889

Xiangyun ZongQuality of Life

Start: 2021-03-01End: 2025-02-28Updated: 2025-06-02

Neoadjuvant vs. Intraoperative vs. Adjuvant Resection Cavity Radiotherapy of Brain Metastases

Active, not recruitingNCT05871307

University Hospital HeidelbergBrain Metastases, Radiotherapy

Start: 2024-02-01End: 2029-05-01Target: 90Updated: 2026-05-27

Swebcg 91:A RT. Breast Conserving Surgery With or Without Radiotherapy for Breast Cancer Patients

Active, not recruitingNCT06637202

Region SkaneBreast Cancer Early Stage Breast Cancer (Stage 1-3)

Start: 1991-01-01End: 2025-12-31Updated: 2024-10-15

Preoperative Radiation Therapy and Immediate Breast Reconstruction

RecruitingNCT06739655

Cancer Research AntwerpBreast Adenocarcinoma, Breast Carcinoma, Breast Neoplasms +2

Start: 2025-02-20End: 2038-02-20Target: 180Updated: 2026-02-04

Safety and Efficacy of IMPT or IMRT for Breast Cancer

RecruitingNCT06826885

Ruijin HospitalBreast Cancer, Efficacy and Safety, Intensity Modulated Radiation Therapy +2

Start: 2024-12-01End: 2029-11-30Target: 500Updated: 2025-02-14

Postoperative Radiotherapy for Early-stage Oral Tongue Squamous Cell Carcinoma Patients With Risk Factors: a Prospective, Multicenter, Randomized Controlled, Open-labelled Trial

RecruitingNCT07402525

Second Affiliated Hospital, School of Medicine, Zhejiang UniversityOral Tongue Squamous Cell Carcinoma

Start: 2026-01-26End: 2031-07-30Target: 190Updated: 2026-02-11

Impact of Postoperative Radiotherapy Versus PD-1 Inhibitor Maintenance on Survival in Resectable Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma

Not yet recruitingNCT07457099

Zhujiang HospitalLocally Advanced Oral Squamous Cell Carcinoma, Locally Advanced Oropharyngeal Squamous Cell Carcinoma

Start: 2026-04-01End: 2028-06-30Target: 85Updated: 2026-03-09

SPARE-1st: Surgery Alone vs Surgery Plus Postoperative Radiotherapy for Sinonasal Adenoid Cystic Carcinoma

Not yet recruitingNCT07563088

Eye & ENT Hospital of Fudan UniversityAdenoid Cystic Carcinoma, Sinonasal Carcinoma

Start: 2026-05-01End: 2032-05-01Target: 200Updated: 2026-05-12

Adjuvant Moderately Hypofractionated Intensity-modulated Radiotherapy for Cervical Cancer

RecruitingNCT07684508

Manni HuangCervical Cancers, Hypofractionated Radiotherapy, Intensity-modulated Radiotherapy

Start: 2026-07-01End: 2030-12-30Target: 154Updated: 2026-07-06

Postoperative Radiotherapy and Lymph Node Dissection After Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma

CompletedNCT07705412

Tongji HospitalEsophageal Squamous Cell Carcinoma (ESCC)

Start: 2025-09-01End: 2026-06-30Updated: 2026-07-15

Related Papers

Preoperative Radiation Therapy and Immediate Breast Reconstruction, a phase 3 randomized controlled trial in the Belgian population (PRADAIIBE): a study protocol

BMC Cancer2026-04-27

Abstract P3-10-22: Preoperative radiotherapy versus postoperative radiotherapy after neoadjuvant chemotherapy in high-risk breast cancer: a prospective, randomized, international multicentre Phase III trial—NeoRad

Clinical Cancer Research2025-06-13

The potential radiosensitization target PFKFB3 is related to response to radiotherapy in SweBCG91RT: a randomized clinical trial with long-term follow-up.

2025-02-28

Transoral Laser or Robotic Surgery Outcomes for Oropharyngeal Carcinoma

JAMA Otolaryngology–Head & Neck Surgery2024-10-1011 citations

Survival outcomes of concurrent radiotherapy and toripalimab versus radiotherapy alone for elderly patients with postoperative head and neck squamous cell carcinoma unfit for cisplatin.

Journal of Clinical Oncology2024-06-011 citations

Feasibility and quality of life of postoperative concurrent radiotherapy and toripalimab in elderly patients with head and neck squamous cell carcinoma (IMPORT trial).

Journal of Clinical Oncology2022-06-01

Phase 2 Study of Adjuvant Radiotherapy Following Narrow‐Margin Hepatectomy in Patients With HCC

Hepatology2021-06-0880 citations

PATHOS: A phase II/III trial of risk-stratified, reduced intensity adjuvant treatment in patients undergoing transoral surgery for human papillomavirus (HPV)-positive oropharyngeal cancer.

Journal of Clinical Oncology2018-05-2017 citations

DARS: a phase III randomised multicentre study of dysphagia- optimised intensity- modulated radiotherapy (Do-IMRT) versus standard intensity- modulated radiotherapy (S-IMRT) in head and neck cancer.

2016-10-0678 citations

PATHOS: a phase II/III trial of risk-stratified, reduced intensity adjuvant treatment in patients undergoing transoral surgery for Human papillomavirus (HPV) positive oropharyngeal cancer

BMC Cancer2015-08-26249 citations