General Anesthesia Using Endotracheal Intubation, Ophthalmologic Surgical Procedure, Sugammadex, Neostigmine, Extubation Readiness
Conditions
Keywords
sugammadex, general anesthesia, ophthalmologic surgical procedures
Brief summary
This study is to invastigate if patients treated with sugammadex compared to neostigmine/atropine would be extubate faster upon emergence of anesthesia.
Detailed description
This is a retrospective case-control study including patients aged 18 years or older who underwent ophthalmic surgeries under general anesthesia with tracheal intubation between 2020 and 2022. Patients who received rocuronium as the sole neuromuscular blocking agent and were maintained with sevoflurane or desflurane and intravenous fentanyl were included. Based on the choice of reversal agent for neuromuscular blockade, patients were divided into two groups: the sugammadex group or the neostigmine group. Patients who underwent emergency surgery or combined surgeries with other specialties were excluded. Patient characteristics, including age, gender, ASA classification, weight, and height, were collected. Anesthesia-related medications were recorded. The time points of anesthesia induction, start and end of surgery, reversal agent administration, and tracheal extubation were documented.
Interventions
DRUGsugammadex
sugammadex used for neuromuscular reversal
Neostigmine and Atropine used for neuromuscular reversal
Sponsors
China Medical University Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
aged 18 years or older ophthalmic surgeries under general anesthesia with tracheal intubation between 2020 and 2022 received rocuronium as the sole neuromuscular blocking agent maintained with sevoflurane or desflurane and intravenous fentanyl
Exclusion criteria
emergency surgery combined surgeries with other specialties
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time From reversal to extubation | Time From reversal to extubation | Time From reversal to extubation |
| Time From the end of surgery to reversal | Time From the end of surgery to reversal | Time From the end of surgery to reversal |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time From induction to the end of surgery | Time From induction to the end of surgery | Time From induction to the end of surgery |
Countries
Taiwan
Outcome results
None listed