Neostigmine + Atropine

DRUG7 trials

Conditions

Colorectal SurgeryEmergence AgitationExtubation ReadinessGeneral Anesthesia Using Endotracheal IntubationNasal SurgeryNeostigmineNeuromuscular BlockadeNeuromuscular Blockade Reversal Agent

Phase 1

Recovery Times of Half Dose Sugammadex and Neostigmine for Rocuronium-induced Neuromuscular Blockade

RecruitingNCT06794450

Universitas PadjadjaranNeuromuscular Blocking Agents, Recovery Time, Reversal of Neuromuscular Blockade

Start: 2024-11-05End: 2025-02-28Target: 60Updated: 2025-01-28

Phase 3

Neuromuscular Blocking Agents on Gastrointestinal Function Following Colorectal Surgery

Not yet recruitingNCT07271875

Xijing HospitalColorectal Surgery, Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus

Start: 2026-01-01End: 2027-12-31Target: 560Updated: 2025-12-09

Phase 4

Efficacy, Safety, and Pharmacokinetics of Sugammadex for Reversal of Neuromuscular Blockade (NMB) in Pediatric Participants (MK-8616-089)

CompletedNCT03351608

Merck Sharp & Dohme LLCNeuromuscular Blockade

Start: 2018-02-12End: 2020-01-28Updated: 2021-02-05

Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)

CompletedNCT03909165

Merck Sharp & Dohme LLCNeuromuscular Blockade

Start: 2019-07-23End: 2023-09-21Updated: 2025-07-25

The Effect of Neostigmine and Sugammadex on the Optic Nerve Sheath Diameter

RecruitingNCT07666984

Cukurova UniversityNeuromuscular Blockade Reversal Agent

Start: 2026-06-04End: 2026-07-10Target: 86Updated: 2026-06-24

Unknown Phase

Sugammadex and Time to Extubation in Ophthalmic Surgery

CompletedNCT06632067

China Medical University HospitalExtubation Readiness, General Anesthesia Using Endotracheal Intubation, Neostigmine +2

Start: 2023-08-01End: 2023-08-31Updated: 2024-10-08

Emergence Agitation

Active, not recruitingNCT07253428

Ain Shams UniversityEmergence Agitation, Nasal Surgery

Start: 2025-10-30End: 2026-01-31Target: 486Updated: 2025-11-28

Related Papers

Sugammadex for Reversal of Neuromuscular Blockade in Neonates and Infants Less than 2 Years Old: Results from a Phase IV Randomized Clinical Trial

Anesthesiology2025-05-055 citations

Sugammadex for reversal of neuromuscular blockade in pediatric patients: Results from a phase IV randomized study

Pediatric Anesthesia2021-12-0822 citations