Effects of Watermelon or Low-fat Cookie Consumption on Wellness

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06323070

Enrollment

Registered

2024-03-21

Start date

2024-03-01

Completion date

2028-12-01

Last updated

2026-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight and Obesity

Brief summary

The objective of the proposed research is to determine the effects of fresh watermelon consumption on physiological indicators of wellness regarding sexual, skin and gut health in adults.

Interventions

OTHERLow-fat cookies

To determine the effects of low-fat cookie consumption on physiological indicators of wellness regarding sexual, skin, and gut health

OTHERWatermelon

To determine the effects of watermelon consumption on physiological indicators of wellness regarding sexual, skin, and gut health

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Generally healthy subjects * BMI 20-40 kg/m2

Exclusion criteria

* Smoker * Pregnant woman * Required antibiotics use * Required dietary supplement use * Required medication of metabolic disorders, mental health and sexual health * Allergy to watermelon or wheat

Design outcomes

Primary

Measure	Time frame	Description
Change of sexual health questionnaire scores	Baseline and week 4	Change of sexual health questionnaire scores will be determined to examine effects of watermelon consumption vs low-fat cookies.
Change of skin hydration scores	Baseline, 1 min post application and week 4 consumption	Change of skin hydration scores will be determined to examine effects of watermelon consumption vs low-fat cookies.
Change of microbiome diversity	Baseline and week 4	Change of skin hydration scores will be determined to examine effects of watermelon consumption vs low-fat cookies.

Secondary

Measure	Time frame	Description
Change of depression questionnaire scores	Baseline and week 4	Change of depression questionnaire scores will be determined to examine effects of watermelon consumption vs low-fat cookies.

Countries

United States

Contacts

CONTACTMee Young Hong, PhD

mhong2@sdsu.edu619-594-2392

PRINCIPAL_INVESTIGATORMee Young Hong, PhD

San Diego State University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026