Acute Respiratory Failure Post Surgical (Diagnosis)
Conditions
Keywords
noninvasive ventilation, COPD, acute respiratory failure
Brief summary
In Qena university hospital a prospective, randomized study was carried out on 100 COPD patients, all were divided into; conventional therapy without NIV (C group) 50 patients or with prophylactic NIV(N group) 50 patients.NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery . Primary endpoint was the acute respiratory events (ARE) .Secondary endpoints were acute respiratory failure (ARF), intubation rate, mortality rate, infectious and non-infectious complications, and ICU stay.
Interventions
DEVICENIV
NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery
Sponsors
South Valley University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Intervention model description
Postoperative NIV
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
1. Inclusion criteria: * Age˃18 years, scheduled for upper abdominal surgery under general anesthesia. * Moderate to very severe COPD (GOLD II to IV). * ASA functional status II or greater. 2.
Exclusion criteria
* Contraindications to the application of NIV. * Sleep apnea syndrome. * Facial deformation. * Inability to follow the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| acute respiratory events | 28days | patients % |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| acute respiratory failure | 28 days | patients % |
| intubation rate | 28 days | patients % |
| ICU mortality | 28 days | patients % |
| ICU length of stay | 28 days | days |
| infectious and non infectious complications | 28 days | patients % |
Countries
Egypt
Outcome results
None listed