NIV

DEVICE16 trials

Sponsors

Institut für Pneumologie Hagen Ambrock eV, Guy's and St Thomas' NHS Foundation Trust, Tufts Medical Center, Southeast University, China, Universitaire Ziekenhuizen KU Leuven

Conditions

Acute Exacerbation of COPDAcute Hypercapnic Respiratory FailureAcute Respiratory Distress in Adult Intensive CareAcute Respiratory FailureAcute Respiratory Failure Post Surgical (Diagnosis)Acute Respiratory Failure Requiring ReintubationAcute on Chronic Respiratory FailureCOPD

Unknown Phase

Intelligent Volume Assured Pressure Support to Improve Sleep Quality and Respiratory Events in Patients With Non Invasive Ventilation

CompletedNCT01986413

Institut für Pneumologie Hagen Ambrock eVChronic Hypercapnic Respiratory Failure, COPD

Start: 2013-07-31End: 2014-06-30Updated: 2015-03-24

ECCO2R as an Adjunct to NIV in AECOPD

CompletedNCT02086084

Guy's and St Thomas' NHS Foundation TrustChronic Obstructive Pulmonary Disease

Start: 2015-12-01End: 2020-12-31Updated: 2021-08-11

Treatment of Dyspnea in Do-not-intubate Patients

TerminatedNCT02114944

Tufts Medical CenterAcute on Chronic Respiratory Failure, Acute Respiratory Failure, Dyspnea

Start: 2014-04-30End: 2023-12-01Target: 400Updated: 2025-05-13

Effects of HFNC on Moderate and Severe Respiratory Failure Patients

Southeast University, ChinaRespiratory Failure

Start: 2016-01-31End: 2017-12-31Target: 246Updated: 2016-02-22

Non-invasive Ventilation and Physical Activity

TerminatedNCT02951572

Universitaire Ziekenhuizen KU LeuvenNeuromuscular Diseases

Start: 2013-02-28End: 2017-06-30Updated: 2020-11-23

High-flow Nasal Cannula Oxygen Therapy With or Without NIV During the Weaning Period

CompletedNCT03121482

Poitiers University HospitalAcute Respiratory Failure Requiring Reintubation

Start: 2017-04-20End: 2018-04-17Updated: 2019-03-13

High Flow Nasal Therapy Versus Noninvasive Ventilation in COPD Exacerbation

CompletedNCT03370666

Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone PalermoCOPD Exacerbation

Start: 2018-02-15End: 2020-04-15Updated: 2020-04-30

Oxygenation Methods and Non-invasive Ventilation in Patients With Acute Respiratory Failure and a do Not Intubate Order

Poitiers University HospitalAcute Respiratory Failure, Cancer, Cardiac Insufficiency +2

Start: 2018-08-07End: 2020-01-31Target: 330Updated: 2018-09-28

Interest of Hypnosis When Setting up Non-invasive Ventilation in a Conscious Patient With COPD and/or Obesity With a BMI Greater Than 30, Suffering Fromacute Respiratory Distress in Adult Intensive Care

RecruitingNCT04220463

Rennes University HospitalAcute Respiratory Distress in Adult Intensive Care, Chronic Obstructive Pulmonary Disease (COPD), Obesity With a BMI Greater Than 30

Start: 2021-11-20End: 2025-11-20Target: 50Updated: 2025-06-24

Extracorporeal CO2 Removal for Acute Decompensation of COPD

WithdrawnNCT04582799

University of BolognaPulmonary Disease, Chronic Obstructive

Start: 2024-08-01End: 2024-08-01Updated: 2025-04-01

Postoperative Noninvasive Ventilation After Upper Abdominal Surgery in Chronic Obstructive Lung Disease

CompletedNCT04877353

South Valley UniversityAcute Respiratory Failure Post Surgical (Diagnosis)

Start: 2019-01-01End: 2020-11-15Updated: 2021-05-07

Effects of High-flow Oxygen Therapy and Non-invasive Ventilation on Lung Volumes and on Upper Airway

RecruitingNCT05643911

University Hospital, MontpellierRespiratory Failure

Start: 2023-01-27End: 2025-01-31Target: 56Updated: 2024-05-29

Comparing High-flow Nasal Cannula Oxygen and Noninvasive Ventilation to Standard Oxygenation in Non-selected ICU Patients Admitted for Hypoxemic ARF

RecruitingNCT05812911

University Hospital, MontpellierAcute Respiratory Failure

Start: 2023-05-23End: 2026-08-23Target: 2100Updated: 2025-05-07

High Flow Nasal Oxygen for Exacerbation COPD

RecruitingNCT06084117

Franciscus GasthuisAcute Exacerbation of COPD

Start: 2024-05-14End: 2026-12-01Target: 40Updated: 2025-08-21

HFNC vs. NIV in Acute COPD Exacerbations

CompletedNCT06495086

Haseki Training and Research HospitalAcute Hypercapnic Respiratory Failure, COPD Exacerbations, Respiratory Failure

Start: 2023-09-01End: 2024-05-01Updated: 2024-07-10

Sonographic Evaluation of Diaphragmatic Function Under Nasal High-flow (NHF) and Non-invasive Ventilation (NIV) in Respiratory Insufficiency

CompletedNCT07050147

Klinikum EmdenRespiratory Insufficiency

Start: 2019-07-01End: 2025-01-01Updated: 2025-07-03

Related Papers

Comparing high-flow nasal cannula oxygen and non-invasive ventilation to standard oxygenation in non-selected intensive care unit patients admitted for acute hypoxaemic respiratory failure: protocol for the KISS (Key oxygenation Interventions in Surgical and non-Surgical patients) adaptive randomised controlled trial.

2025-10-20

Study protocol for the HONIVAH trial: a single-centre randomised study assessing high-flow oxygen therapy versus non-invasive ventilation on lung volumes and the upper airway <b>in hypoxemic critically ill patients</b>

BMJ Open2025-09-01

Physiological Assessment of ECCO <sub>2</sub> R on the Work of Breathing in Exacerbations of COPD

COPD Journal of Chronic Obstructive Pulmonary Disease2024-12-05

A high-flow nasal cannula versus noninvasive ventilation in acute exacerbations of chronic obstructive pulmonary disease.

2024-10-284 citations

A randomised controlled trial of non-invasive ventilation compared with extracorporeal carbon dioxide removal for acute hypercapnic exacerbations of chronic obstructive pulmonary disease.

2022-04-2115 citations

Beneficial Effects of Noninvasive Ventilation after Extubation in Obese or Overweight Patients: A <i>Post Hoc</i> Analysis of a Randomized Clinical Trial

American Journal of Respiratory and Critical Care Medicine2021-11-2367 citations

Extracorporeal carbon dioxide removal for treatment of exacerbated chronic obstructive pulmonary disease (ORION): study protocol for a randomised controlled trial.

2021-10-196 citations

Non-invasive ventilation versus high-flow nasal oxygen for postextubation respiratory failure in ICU: a post-hoc analysis of a randomized clinical trial

Critical Care2021-06-2825 citations

Non-invasive ventilation alternating with high-flow nasal oxygen versus high-flow nasal oxygen alone after extubation in COPD patients: a post hoc analysis of a randomized controlled trial

Annals of Intensive Care2021-02-0928 citations

Comparison of high-flow nasal oxygen therapy and non-invasive ventilation in ICU patients with acute respiratory failure and a do-not-intubate orders: a multicentre prospective study OXYPAL

BMJ Open2021-02-019 citations

High flow nasal therapy versus noninvasive ventilation as initial ventilatory strategy in COPD exacerbation: a multicenter non-inferiority randomized trial.

2020-12-1481 citations

In vivo carbon dioxide clearance of a low-flow extracorporeal carbon dioxide removal circuit in patients with acute exacerbations of chronic obstructive pulmonary disease

Perfusion2020-01-1113 citations

Effect of Postextubation High-Flow Nasal Oxygen With Noninvasive Ventilation vs High-Flow Nasal Oxygen Alone on Reintubation Among Patients at High Risk of Extubation Failure

JAMA2019-10-02323 citations

Extracorporeal carbon dioxide removal for acute hypercapnic exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial.

2019-07-308 citations

High-flow nasal therapy versus noninvasive ventilation in COPD patients with mild-to-moderate hypercapnic acute respiratory failure: study protocol for a noninferiority randomized clinical trial.

2019-07-2228 citations

High-flow nasal cannula oxygen therapy alone or with non-invasive ventilation during the weaning period after extubation in ICU: the prospective randomised controlled HIGH-WEAN protocol

BMJ Open2018-09-0114 citations