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Concentration of MitoQ in Human Skeletal Muscle

Concentration of Mitoquinone Mesylate in Skeletal Muscle After a Single Oral Dose of MitoQ

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04098510
Acronym
MitoQ/muscle
Enrollment
10
Registered
2019-09-23
Start date
2019-09-08
Completion date
2020-09-30
Last updated
2019-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Mitochondria-targeted antioxidant, Skeletal muscle biopsies

Brief summary

The purpose of this study is to determine mitoquinone mesylate concentration levels in skeletal muscle samples obtained after intake of an acute oral dose of MitoQ.

Interventions

DIETARY_SUPPLEMENTMitoQ

Subjects ingest 8x20 mg MitoQ capsules

Sponsors

University of Copenhagen
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy, * Male * 18-40 years of age

Exclusion criteria

* Previous use of MitoQ or CoQ-10 within 30 days of screening appointment * Ongoing use of MitoQ * Smoking * Ongoing treatment with medications * Disease deemed by the MD to infer a risk to participate in the trial

Design outcomes

Primary

MeasureTime frameDescription
Muscle mitoquinone mesylate concentrationBefore oral administration of MitoQConcentration of mitoquinone mesylate in skeletal muscle

Secondary

MeasureTime frameDescription
Blood mitoquinone mesylate concentrationBefore as well as 0.5, 1, 1.5, 2, 3, 4 and 5 hours after oral administration of MitoQConcentration of mitoquinone mesylate in venous blood

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026