Healthy
Conditions
Keywords
Mitochondria-targeted antioxidant, Skeletal muscle biopsies
Brief summary
The purpose of this study is to determine mitoquinone mesylate concentration levels in skeletal muscle samples obtained after intake of an acute oral dose of MitoQ.
Interventions
Subjects ingest 8x20 mg MitoQ capsules
Sponsors
Study design
Eligibility
Inclusion criteria
* Healthy, * Male * 18-40 years of age
Exclusion criteria
* Previous use of MitoQ or CoQ-10 within 30 days of screening appointment * Ongoing use of MitoQ * Smoking * Ongoing treatment with medications * Disease deemed by the MD to infer a risk to participate in the trial
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Muscle mitoquinone mesylate concentration | Before oral administration of MitoQ | Concentration of mitoquinone mesylate in skeletal muscle |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Blood mitoquinone mesylate concentration | Before as well as 0.5, 1, 1.5, 2, 3, 4 and 5 hours after oral administration of MitoQ | Concentration of mitoquinone mesylate in venous blood |
Countries
Denmark