MitoQ

DIETARY_SUPPLEMENT20 trials

Sponsors

Antipodean Pharmaceuticals, Inc., University of Delaware, University of Colorado, Boulder, University of Nebraska, Virginia Commonwealth University

Conditions

AgingAlzheimer Disease, Early OnsetAmyotrophic Lateral Sclerosis ALSBlood PressureCardiovascular DiseasesCardiovascular Risk FactorChronic Kidney DiseaseChronic Obstructive Pulmonary Disease

Early Phase 1

Mitochondrial Derived Reactive Oxygen Species on Cardiovascular Health in Chronic Obstructive Pulmonary Disease (COPD)

TerminatedNCT05605548

Virginia Commonwealth UniversityChronic Obstructive Pulmonary Disease

Start: 2023-02-16End: 2024-07-30Updated: 2025-02-27

MitoQ and Exercise Effects on Vascular Health

Active, not recruitingNCT05686967

University of Colorado, DenverAging, Menopause

Start: 2023-01-16End: 2025-11-30Updated: 2025-03-25

Phase 2

A Trial of MitoQ for the Treatment of People With Parkinson's Disease

CompletedNCT00329056

Antipodean Pharmaceuticals, Inc.Parkinson's Disease

Start: 2006-05-31End: 2007-11-30Updated: 2010-07-21

MARVEL: Mitochondrial Anti-oxidant Therapy to Resolve Inflammation in Ulcerative Colitis

Active, not recruitingNCT04276740

University of EdinburghUlcerative Colitis Flare

Start: 2022-05-31End: 2026-11-30Updated: 2026-01-13

Mitochondrial-targeted Antioxidant Supplementation for Improving Age-related Vascular Dysfunction in Humans

Active, not recruitingNCT04851288

University of Colorado, BoulderAging

Start: 2021-04-02End: 2026-12-31Target: 112Updated: 2025-11-12

Mini-MARVEL - Mitochondrial Antioxidant Therapy in Ulcerative Colitis

WithdrawnNCT05539625

University of EdinburghUlcerative Colitis

Start: 2025-09-01End: 2026-10-31Updated: 2026-01-09

MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction

RecruitingNCT06191965

Mclean HospitalCognitive Impairment, Mitochondrial Alteration, Schizophrenia and Related Disorders

Start: 2024-06-01End: 2027-01-31Target: 100Updated: 2025-09-25

Effects of an Antioxidant Supplement on Blood Vessel Health

RecruitingNCT06424756

University of GeorgiaHealthy

Start: 2024-07-01End: 2030-03-31Target: 60Updated: 2024-12-09

ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize Treatments

CompletedNCT06429059

Duke UniversityAmyotrophic Lateral Sclerosis ALS

Start: 2024-06-12End: 2025-06-24Updated: 2025-09-26

Phase 4

Mitochondrial Oxidative Stress and Vascular Health in Chronic Kidney Disease

University of DelawareChronic Kidney Disease

Start: 2017-07-01End: 2019-09-30Target: 24Updated: 2019-04-25

Unknown Phase

The Efficacy of Oral Mitoquinone (MitoQ) Supplementation for Improving Physiological in Middle-aged and Older Adults

CompletedNCT02597023

University of Colorado, BoulderAging

Start: 2015-09-30End: 2017-12-31Updated: 2018-04-12

Impacts of Mitochondrial-targeted Antioxidant on Peripheral Artery Disease Patients

CompletedNCT03506633

University of NebraskaPeripheral Arterial Disease, Peripheral Artery Disease

Start: 2018-09-05End: 2022-01-17Updated: 2025-04-01

Effects of Mitochondrial-targeted Antioxidant on Mild Cognitive Impairment (MCI) Patients

WithdrawnNCT03514875

University of NebraskaAlzheimer Disease, Early Onset, Mild Cognitive Impairment

Start: 2019-11-11End: 2022-07-18Updated: 2023-08-15

Chronic Kidney Disease and Heart Failure With Preserved Ejection Fraction: The Role of Mitochondrial Dysfunction

CompletedNCT03960073

Virginia Commonwealth UniversityHeart Failure With Preserved Ejection Fraction, Renal Insufficiency, Chronic

Start: 2019-07-31End: 2022-09-30Updated: 2022-12-19

Concentration of MitoQ in Human Skeletal Muscle

University of CopenhagenHealthy

Start: 2019-09-08End: 2020-09-30Target: 10Updated: 2019-09-23

Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia

RecruitingNCT04109820

University of PittsburghSickle Cell Disease

Start: 2020-03-01End: 2027-06-30Target: 15Updated: 2025-06-19

The Influence of Mitochondrial-Derived Reactive Oxygen Species on Racial Disparities in Neurovascular Function

RecruitingNCT04334135

Auburn UniversityBlood Pressure, Cardiovascular Risk Factor, Racial Disparities +1

Start: 2020-10-02End: 2025-08-31Target: 60Updated: 2024-05-29

Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle

CompletedNCT04558190

University of CopenhagenInsulin Resistance

Start: 2020-09-02End: 2021-11-01Updated: 2021-12-02

Mitochondria Oxidative Stress and Vascular Health Study

CompletedNCT05561556

Auburn UniversityCardiovascular Diseases, Hypertension, Racism +1

Start: 2022-12-06End: 2025-09-26Updated: 2025-09-29

MitoQ & Cardiopulmonary Responses During Exercise

CompletedNCT06069245

Ball State UniversityHealthy

Start: 2022-09-14End: 2023-04-30Updated: 2023-10-05

Related Papers

Do not sleep on vitamin D: vitamin D is associated with sleep variability in apparently healthy adults.

2025-01-284 citations

Mitochondrial-targeted antioxidant supplementation for improving age-related vascular dysfunction in humans: A study protocol

Frontiers in Physiology2022-09-1532 citations

Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults

Hypertension2018-04-16404 citations

Mitochondrial‐Targeted Antioxidant (MitoQ) Improves Vascular Function in Healthy Late Middle‐Aged and Older Adults

The FASEB Journal2018-04-011 citations