Healthy Volunteers (Meningococcal Infection)
Conditions
Brief summary
The primary objective of the study was to demonstrate the non-inferiority of the antibody responses to meningococcal serogroups A, C, W, and Y (MenACYW) in terms of serum bactericidal assay using human complement (hSBA) vaccine seroprotection (antibody titer greater than or equal to \[\>=\] 1:8) when MenACYW Conjugate vaccine was administered concomitantly with Bexsero® in the second year of life compared to when MenACYW Conjugate vaccine was given alone. The secondary objectives were to compare the hSBA antibody response in terms of geometric mean titers (GMTs) against meningococcal serogroups A, C, W, and Y when MenACYW Conjugate vaccine was administered concomitantly with Bexsero® or when MenACYW Conjugate vaccine was given alone in the second year of life; to describe the hSBA and serum bactericidal assay using baby rabbit complement (rSBA) antibody responses against meningococcal serogroups A, C, W, and Y before and after the 1st dose of MenACYW Conjugate vaccine administered at 3 months of age, before and after the 2nd dose of MenACYW Conjugate vaccine administered at 12 to 13 months of age for Group 1 and Group 2; to describe the hSBA and rSBA antibody persistence against meningococcal serogroups A, C, W, and Y after the 1st dose of MenACYW Conjugate vaccine administered at 3 months of age for Group 1 and Group 2.
Detailed description
Study duration per participant was approximately 11 to 12 months.
Interventions
Pharmaceutical form: solution for injection; route of administration: intramuscular, 0.5 mL
Pharmaceutical form: suspension for injection; route of administration: deep intramuscular, 0.5 mL
Pharmaceutical form: powder and suspension for suspension injection; route of administration: deep intramuscular, 0.5 mL
Pharmaceutical form: oral suspension; route of administration: oral, 1.5 mL
Pharmaceutical form: suspension for injection; route of administration: intramuscular, 0.5 mL
Sponsors
Study design
Eligibility
Inclusion criteria
* Aged \>= 56 to less than or equal to (\<=) 89 days on the day of the first study visit. * Born at full term of pregnancy (\>= 37 weeks) and with a birth weight \>= 2.5 kilogram (kg) (or 5 lb and 8 oz). * Informed consent form had been signed and dated by the parent(s) or other legally acceptable representative (and by an independent witness if required by local regulations). * Participant and parent/legally acceptable representative were able to attend all scheduled visits and to comply with all trial procedures.
Exclusion criteria
\-- Participation at the time of study enrollment (or in the 4 weeks preceding the first trial vaccination) or planned participation during the present trial period in another clinical trial investigating a vaccine, drug, medical device, or medical procedure. * Receipt of any vaccine in the 4 weeks preceding the first trial vaccination (at Visit 1) or planned receipt of any vaccine in the 4 weeks before and/or following any trial vaccination except for influenza vaccination, which may be received at a gap of at least 2 weeks before or 2 weeks after any study vaccines. This exception includes monovalent pandemic influenza vaccines and multivalent influenza vaccines. * Previous vaccination against meningococcal disease with either the trial vaccine or another vaccine (i.e., mono- or polyvalent, polysaccharide, or conjugate meningococcal vaccine containing serogroups A, C, W, or Y; or meningococcal B serogroup-containing vaccine). * Previous vaccination (before Visit 1) with any pneumococcal, diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b (Hib), poliovirus, and/or rotavirus vaccines. Receipt of BCG vaccine at birth was acceptable. * Receipt of immune globulins, blood or blood-derived since birth. * Known or suspected congenital or acquired immunodeficiency, including Severe Combined Immunodeficiency disorder (SCID); or receipt of immunosuppressive therapy, such as anti-cancer chemotherapy or radiation therapy; or long-term systemic corticosteroid therapy (prednisone or equivalent for more than 2 consecutive weeks) since birth. * History of any neurologic disorders, including any seizures and progressive neurologic disorders or encephalopathy. * History of Neisseria meningitidis infection, confirmed either clinically, serologically, or microbiologically. * History of diphtheria, tetanus, pertussis, poliomyelitis, Hib, hepatitis B, Streptococcus pneumoniae, and/or rotavirus infection or disease. * At high risk for meningococcal infection during the trial (specifically, but not limited to, participants with persistent complement deficiency, with anatomic or functional asplenia, or participants travelling to countries with high endemic or epidemic disease). * History of Guillain-Barré syndrome. * Known systemic hypersensitivity to any of the vaccine components, or history of a life-threatening reaction to the vaccines used in the trial or to a vaccine containing any of the same substances including neomycin, kanamycin, polymyxin, formaldehyde, and latex. * Hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency. * History of intussusception or uncorrected congenital malformation of the gastrointestinal tract that would predispose to intussusception. * Verbal report of thrombocytopenia, contraindicating intramuscular vaccination in the investigator's opinion. * Bleeding disorder, or receipt of anticoagulants in the 3 weeks preceding inclusion, contraindicating intramuscular vaccination. * Chronic illness that, in the opinion of the investigator, was at a stage where it might interfere with trial conduct or completion. * Any condition which, in the opinion of the investigator, might interfere with the evaluation of the study objectives, including planning to leave the area of the study site before the end of the study. * Moderate or severe acute illness/infection (according to investigator judgment), or febrile illness (temperature \>= 38.0°C), or diarrhea or vomiting on the day of vaccination. A prospective participant should not be included in the study until the condition had resolved or the febrile event has subsided. * Identified as a natural or adopted child of the Investigator or employee with direct involvement in the proposed study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of Participants With Antibody Titers Greater Than or Equal to (>=) 1:8 Against Meningococcal Serogroups A, C, Y, and W Measured by hSBA After Vaccination: Groups 1 and 2 - PPAS3 | 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by serum bactericidal assay using human complement (hSBA) assay. Percentage of participants with antibody titers \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. Data for this outcome measure was not planned to be collected and analyzed for Group 3. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Before vaccination at the age of 3 months | GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by hSBA. Infancy was defined as up to 4 months of age. Titers were expressed in terms of 1/dilution. Data for this outcome measure was not planned to be collected and analyzed for Group 3. |
| Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) | GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by hSBA. Infancy was defined as up to 4 months of age. Titers were expressed in terms of 1/dilution. Data for this outcome measure was not planned to be collected and analyzed for Group 3. |
| Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Before vaccination at the age of 12 to 13 months | GMTs of antibodies against meningococcal serogroups A, C, Y, and W were measured by hSBA. Infancy was defined as up to 4 months of age. Titers were expressed in terms of 1/dilution. |
| Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | GMTs of antibodies against meningococcal serogroups A, C, Y, and W were measured by hSBA. Titers were expressed in terms of 1/dilution. |
| Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Before vaccination at the age of 3 months | GMTs of antibodies against meningococcal serogroups A, C, Y, and W were measured by serum bactericidal assay using baby rabbit complement (rSBA). Infancy was defined as up to 4 months of age. Titers were expressed in terms of 1/dilution. |
| Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) | GMTs of antibodies against meningococcal serogroups A, C, Y, and W were measured by rSBA. Infancy was defined as up to 4 months of age. Titers were expressed in terms of 1/dilution. |
| Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Before vaccination at the age of 12 to 13 months | GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by rSBA. Titers were expressed in terms of 1/dilution. |
| Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by rSBA. Titers were expressed in terms of 1/dilution. |
| Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Before vaccination at the age of 3 months | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.4 and \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.4 and \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Before vaccination at the age of 12 to 13 months | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.4 and \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Percentage of participants with antibody titers \>=1.4 and \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Before vaccination at the age of 3 months | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.8 and \>=1:128 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.8 and \>=1:128 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Before vaccination at the age of 12 to 13 months | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.8 and \>=1:128 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Percentage of participants with antibody titers \>=1.8 and \>=1:128 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Before vaccination at the age of 3 months, 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Fold-rise was calculated as ratio of post-vaccination titer (i.e., 30 days post-vaccination at the age of 3 months) to pre-dose titer at the age of 3 months. Infancy was defined as up to 4 months of age. |
| Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Before vaccination at the age of 3 months, 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Fold-rise was calculated as ratio of post-vaccination titer (i.e., 30 days post-vaccination at the age of 12 to 13 months) to pre-dose titer before vaccination at the age of 3 months. |
| Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Before vaccination at the age of 3 months, 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Fold-rise was calculated as ratio of post-vaccination titer (i.e., 30 days post-vaccination at the age of 3 months) to pre-dose titer at the age of 3 months. Infancy was defined as up to 4 months of age. |
| Geometric Mean Titers (GMTs) of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by hSBA. Titers were expressed in terms of 1/dilution. |
| Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Before vaccination at the age of 3 months up to 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) | The hSBA vaccine seroresponse against serogroups A, C, Y, and W was defined as post-vaccination hSBA titer \>=1:16 for participants with pre-vaccination hSBA titer \<1:8 or at least a 4-fold increase in hSBA titers from pre to post-vaccination for participants with pre-vaccination hSBA titers \>=1:8. Infancy was defined as up to 4 months of age. |
| Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Before vaccination at the age of 3 months up to 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | The hSBA vaccine seroresponse against serogroups A, C, Y, and W was defined as post-vaccination hSBA titer \>=1:16 for participants with pre-vaccination hSBA titer \<1:8 or at least a 4-fold increase in hSBA titers from pre to post-vaccination for participants with pre-vaccination hSBA titers \>=1:8. |
| Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Before vaccination at the age of 3 months up to 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) | The rSBA vaccine seroresponse against serogroups A, C, Y, and W was defined as post-vaccination rSBA titer \>=1:32 for participants with pre-vaccination rSBA titer \<1:8 or at least a 4-fold increase in hSBA titers from pre to post-vaccination for participants with pre-vaccination hSBA titers \>=1:8. Infancy was defined as up to 4 months of age. |
| Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Before vaccination at the age of 3 months up to 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | The rSBA vaccine seroresponse against serogroups A, C, Y, and W was defined as post-vaccination rSBA titer \>=1:32 for participants with pre-vaccination rSBA titer \<1:8 or at least a 4-fold increase in hSBA titers from pre to post-vaccination for participants with pre-vaccination hSBA titers \>=1:8. |
| Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Before vaccination at the age of 3 months | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Percentage of participants with hSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with hSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Before vaccination at the age of 12 to 13 months | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with hSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192; \>=1:16384; \>=1:32768; \>=1:65536 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) and before vaccination at the age of 12-13 months | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Percentage of participants with hSBA antibody titers \>=1.4 and \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Percentage of participants with hSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192; \>=1:16384; \>=1:32768; \>=1:65536 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Before vaccination at the age of 3 months | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with rSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with rSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Before vaccination at the age of 12 to 13 months | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with rSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192; \>=1:16384; \>=1:32768 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Percentage of participants with rSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192; \>=1:16384; \>=1:32768 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) and before vaccination at the age of 12-13 months | GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by hSBA. Titers were expressed in terms of 1/dilution. |
| Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) and before vaccination at the age of 12-13 months | GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by rSBA. Titers were expressed in terms of 1/dilution. |
| Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) and before vaccination at the age of 12-13 months | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Percentage of participants with rSBA antibody titers \>=1:8 and \>=1:128 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. |
| Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Within 7 days post any vaccination | A solicited reaction (SR) was defined as an expected adverse reaction (AR) (sign or symptom) observed and reported under the conditions (nature and onset) pre-listed (i.e., solicited) in the protocol and case report form (CRF) and considered as related to vaccination. Solicited injection site reactions included injection site tenderness, injection site erythema, and injection site swelling and were planned to be collected and reported for each vaccine separately; and not planned to be collected for Rotavirus vaccine as the vaccine was administered orally, and no injection site reactions were expected to occur. Reported AEs for each arm were presented as pre-specified in the study protocol. Here, '0' in number analyzed field for MenACYW categories signifies that no participant was evaluable because in Group 3 MenACYW vaccine was not administered. |
| Number of Participants With Solicited Systemic Reactions After Any Vaccination | Within 7 days after any vaccination | A SR was an expected AR (sign or symptom) observed and reported under the conditions (nature and onset) prelisted (i.e., solicited) in the CRB and considered as related to the product administered. Solicited systemic reactions included fever, vomiting, crying abnormal, drowsiness, appetite lost, and irritability. Reported AEs for each arm were presented as pre-specified in the study protocol. |
| Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Before vaccination at the age of 3 months, 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months) | Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Fold-rise was calculated as ratio of post-vaccination titer (i.e., 30 days post-vaccination at the age of 12 to 13 months) to pre-dose titer before vaccination at the age of 3 months. |
Countries
United Kingdom
Participant flow
Recruitment details
Study was conducted at 16 sites in United Kingdom from 10 October 2018 to 05 December 2022.
Pre-assignment details
A total of 788 participants were enrolled and randomized in the study.
Participants by arm
| Arm | Count |
|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) Participants aged 2 months (at the time of enrollment) received MenACYW Conjugate vaccine at 3 months and at 12 to 13 months of age, Bexsero® at 2, 4, and 12 to 13 months of age along with Infanrix hexa® vaccine at 2, 3, and 4 months of age; Rotarix® vaccine at 2 and 3 months of age; and Prevenar 13® vaccine at 2 and 4 months of age. | 314 |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) Participants aged 2 months (at the time of enrollment) received MenACYW Conjugate vaccine at 3 months and at 12 to 13 months of age, Bexsero® at 2 and 4 months of age along with Infanrix hexa® vaccine at 2, 3, and 4 months of age; Rotarix® vaccine at 2 and 3 months of age; and Prevenar 13® vaccine at 2 and 4 months of age. | 316 |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) Participants aged 2 months (at the time of enrollment) received Bexsero® at 2, 4, and 12 to 13 months of age along with Infanrix hexa® vaccine at 2, 3, and 4 months of age; Rotarix® vaccine at 2 and 3 months of age; and Prevenar 13® vaccine at 2 and 4 months of age. | 158 |
| Total | 788 |
Withdrawals & dropouts
| Period | Reason | FG000 | FG001 | FG002 |
|---|---|---|---|---|
| Overall Study | Adverse Event | 2 | 0 | 0 |
| Overall Study | Lost to Follow-up | 0 | 1 | 0 |
| Overall Study | Screen failure | 0 | 1 | 0 |
| Overall Study | Withdrawal by parent/legally acceptable representative | 11 | 9 | 8 |
Baseline characteristics
| Characteristic | Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Total | Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) |
|---|---|---|---|---|
| Age, Continuous | 64.7 days STANDARD_DEVIATION 6.88 | 64.4 days STANDARD_DEVIATION 6.85 | 64.8 days STANDARD_DEVIATION 7.03 | 63.9 days STANDARD_DEVIATION 6.73 |
| Race (NIH/OMB) American Indian or Alaska Native | 0 Participants | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Asian | 1 Participants | 9 Participants | 4 Participants | 4 Participants |
| Race (NIH/OMB) Black or African American | 0 Participants | 2 Participants | 0 Participants | 2 Participants |
| Race (NIH/OMB) More than one race | 4 Participants | 18 Participants | 4 Participants | 10 Participants |
| Race (NIH/OMB) Native Hawaiian or Other Pacific Islander | 0 Participants | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Unknown or Not Reported | 9 Participants | 15 Participants | 2 Participants | 4 Participants |
| Race (NIH/OMB) White | 300 Participants | 744 Participants | 148 Participants | 296 Participants |
| Sex/Gender, Customized Female | 148 Participants | 383 Participants | 81 Participants | 154 Participants |
| Sex/Gender, Customized Male | 166 Participants | 404 Participants | 77 Participants | 161 Participants |
| Sex/Gender, Customized Missing | 0 Participants | 1 Participants | 0 Participants | 1 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk | EG002 affected / at risk |
|---|---|---|---|
| deaths Total, all-cause mortality | 0 / 314 | 0 / 314 | 0 / 157 |
| other Total, other adverse events | 310 / 314 | 310 / 314 | 155 / 157 |
| serious Total, serious adverse events | 18 / 314 | 34 / 314 | 7 / 157 |
Outcome results
Percentage of Participants With Antibody Titers Greater Than or Equal to (>=) 1:8 Against Meningococcal Serogroups A, C, Y, and W Measured by hSBA After Vaccination: Groups 1 and 2 - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by serum bactericidal assay using human complement (hSBA) assay. Percentage of participants with antibody titers \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
Time frame: 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on Per-Protocol Analysis Set 3 (PPAS3) defined for accessing ACYW immune response data for participants who received at least 1 dose of study vaccine and had valid post-vaccination serology results of 2nd year of life, with no relevant protocol deviation. Here, 'number analyzed' = participants with available data for each specified category.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Antibody Titers Greater Than or Equal to (>=) 1:8 Against Meningococcal Serogroups A, C, Y, and W Measured by hSBA After Vaccination: Groups 1 and 2 - PPAS3 | Serogroup A | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Antibody Titers Greater Than or Equal to (>=) 1:8 Against Meningococcal Serogroups A, C, Y, and W Measured by hSBA After Vaccination: Groups 1 and 2 - PPAS3 | Serogroup Y | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Antibody Titers Greater Than or Equal to (>=) 1:8 Against Meningococcal Serogroups A, C, Y, and W Measured by hSBA After Vaccination: Groups 1 and 2 - PPAS3 | Serogroup W | 99.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Antibody Titers Greater Than or Equal to (>=) 1:8 Against Meningococcal Serogroups A, C, Y, and W Measured by hSBA After Vaccination: Groups 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Antibody Titers Greater Than or Equal to (>=) 1:8 Against Meningococcal Serogroups A, C, Y, and W Measured by hSBA After Vaccination: Groups 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Antibody Titers Greater Than or Equal to (>=) 1:8 Against Meningococcal Serogroups A, C, Y, and W Measured by hSBA After Vaccination: Groups 1 and 2 - PPAS3 | Serogroup A | 99.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Antibody Titers Greater Than or Equal to (>=) 1:8 Against Meningococcal Serogroups A, C, Y, and W Measured by hSBA After Vaccination: Groups 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Antibody Titers Greater Than or Equal to (>=) 1:8 Against Meningococcal Serogroups A, C, Y, and W Measured by hSBA After Vaccination: Groups 1 and 2 - PPAS3 | Serogroup Y | 100 percentage of participants |
Geometric Mean Titers (GMTs) of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by hSBA. Titers were expressed in terms of 1/dilution.
Time frame: 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (GEOMETRIC_MEAN) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers (GMTs) of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 1214 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers (GMTs) of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 963 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers (GMTs) of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 454 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers (GMTs) of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 578 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers (GMTs) of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 528 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers (GMTs) of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 205 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers (GMTs) of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 434 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers (GMTs) of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 744 titers |
Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1
GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by hSBA. Infancy was defined as up to 4 months of age. Titers were expressed in terms of 1/dilution. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
Time frame: 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months)
Population: Analysis was performed PPAS1. Here, 'number analyzed' = participants with available data for each specified category.
| Arm | Measure | Group | Value (GEOMETRIC_MEAN) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 10.8 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 78.0 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 9.44 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 4.67 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 3.81 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 9.63 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 6.33 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 61.2 titers |
Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
GMTs of antibodies against meningococcal serogroups A, C, Y, and W were measured by hSBA. Titers were expressed in terms of 1/dilution.
Time frame: 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (GEOMETRIC_MEAN) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 1214 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 454 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 963 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 578 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 744 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 205 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 528 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 434 titers |
Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1
GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by hSBA. Infancy was defined as up to 4 months of age. Titers were expressed in terms of 1/dilution. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
Time frame: Before vaccination at the age of 3 months
Population: Analysis was performed on per-protocol analysis set 1 (PPAS1) defined for accessing ACYW immune response data for participants who received at least 1 dose of study vaccine and had valid post-vaccination serology result of infancy (up to 4 months age) vaccination stage, with no relevant protocol deviations. Here, 'number analyzed' = participants with available data for each specified category.
| Arm | Measure | Group | Value (GEOMETRIC_MEAN) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 8.52 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 3.70 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 3.26 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 2.52 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 2.15 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 7.22 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 2.58 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 3.84 titers |
Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3
GMTs of antibodies against meningococcal serogroups A, C, Y, and W were measured by hSBA. Infancy was defined as up to 4 months of age. Titers were expressed in terms of 1/dilution.
Time frame: Before vaccination at the age of 12 to 13 months
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (GEOMETRIC_MEAN) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 30.2 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 45.8 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 25.2 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 34.6 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 10.4 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 9.90 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 22.6 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 8.44 titers |
Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2
GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by hSBA. Titers were expressed in terms of 1/dilution.
Time frame: 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) and before vaccination at the age of 12-13 months
Population: Analysis was performed on per-protocol analysis set 2 (PPAS2) defined for accessing ACYW immune response data for participants who received at least 1 dose of study vaccine in infancy and had valid post-vaccination serology results at 12 to13 months of age, with no relevant protocol violations. Here, 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (GEOMETRIC_MEAN) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup A: Before 12-13 months vaccination | 46.1 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup C: 30 days after 3-month vaccination | 95.1 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup C: Before 12-13 months vaccination | 24.4 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup Y: 30 days after 3-month vaccination | 9.69 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup Y: Before 12-13 months vaccination | 21.4 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup W: 30 days after 3-month vaccination | 4.32 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup W: Before 12-13 months vaccination | 29.4 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup A: 30 days after 3-month vaccination | 12.7 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup A: 30 days after 3-month vaccination | 9.28 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup A: Before 12-13 months vaccination | 31.4 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup Y: Before 12-13 months vaccination | 12.4 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup C: 30 days after 3-month vaccination | 59.4 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup W: Before 12-13 months vaccination | 11.2 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup C: Before 12-13 months vaccination | 16.6 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup W: 30 days after 3-month vaccination | 3.62 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup Y: 30 days after 3-month vaccination | 4.95 titers |
Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1
GMTs of antibodies against meningococcal serogroups A, C, Y, and W were measured by rSBA. Infancy was defined as up to 4 months of age. Titers were expressed in terms of 1/dilution.
Time frame: 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months)
Population: Analysis was performed on PPAS1. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (GEOMETRIC_MEAN) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 13.7 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 251 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 152 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 87.1 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 50.8 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 20.7 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 124 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 347 titers |
Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by rSBA. Titers were expressed in terms of 1/dilution.
Time frame: 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (GEOMETRIC_MEAN) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 1741 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 2620 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 1396 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 2491 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 1532 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 1508 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 2566 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 1414 titers |
Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1
GMTs of antibodies against meningococcal serogroups A, C, Y, and W were measured by serum bactericidal assay using baby rabbit complement (rSBA). Infancy was defined as up to 4 months of age. Titers were expressed in terms of 1/dilution.
Time frame: Before vaccination at the age of 3 months
Population: Analysis was performed on PPAS1. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (GEOMETRIC_MEAN) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 2.00 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 2.88 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 2.68 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 2.89 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 2.00 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 2.00 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 2.70 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 3.77 titers |
Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3
GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by rSBA. Titers were expressed in terms of 1/dilution.
Time frame: Before vaccination at the age of 12 to 13 months
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (GEOMETRIC_MEAN) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 32.0 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 58.0 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 58.0 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 8.00 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 8.00 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 169 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 6.96 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 3.48 titers |
Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2
GMTs of antibody against meningococcal serogroups A, C, Y, and W were measured by rSBA. Titers were expressed in terms of 1/dilution.
Time frame: 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) and before vaccination at the age of 12-13 months
Population: Analysis was performed on PPAS2. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (GEOMETRIC_MEAN) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup A: 30 days after 3-month vaccination | 80.6 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup A: Before 12-13 months vaccination | 21.5 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup C: 30 days after 3-month vaccination | 431 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup C: Before 12-13 months vaccination | 38.1 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup Y: 30 days after 3-month vaccination | 323 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup Y: Before 12-13 months vaccination | 69.8 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup W: 30 days after 3-month vaccination | 256 titers |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup W: Before 12-13 months vaccination | 16.0 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup W: Before 12-13 months vaccination | 4.67 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup A: 30 days after 3-month vaccination | 18.0 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup Y: 30 days after 3-month vaccination | 102 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup A: Before 12-13 months vaccination | 27.4 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup W: 30 days after 3-month vaccination | 90.5 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup C: 30 days after 3-month vaccination | 144 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup Y: Before 12-13 months vaccination | 20.7 titers |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Geometric Mean Titers of Antibodies Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W: Group 1 and 2 - PPAS2 | Serogroup C: Before 12-13 months vaccination | 11.8 titers |
Number of Participants With Solicited Injection Site Reactions After Any Vaccination
A solicited reaction (SR) was defined as an expected adverse reaction (AR) (sign or symptom) observed and reported under the conditions (nature and onset) pre-listed (i.e., solicited) in the protocol and case report form (CRF) and considered as related to vaccination. Solicited injection site reactions included injection site tenderness, injection site erythema, and injection site swelling and were planned to be collected and reported for each vaccine separately; and not planned to be collected for Rotavirus vaccine as the vaccine was administered orally, and no injection site reactions were expected to occur. Reported AEs for each arm were presented as pre-specified in the study protocol. Here, '0' in number analyzed field for MenACYW categories signifies that no participant was evaluable because in Group 3 MenACYW vaccine was not administered.
Time frame: Within 7 days post any vaccination
Population: Analysis was performed on safety analysis set. Here, 'number analyzed' = participants with available data for each specified category.
| Arm | Measure | Group | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Prevnar 13: Tenderness | 195 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Prevnar 13: Erythema | 214 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Bexsero: Tenderness | 266 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Prevnar 13: Swelling | 140 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Bexsero: Erythema | 271 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | MenACYW conjugate vaccine: Tenderness | 198 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Bexsero: Swelling | 234 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | MenACYW conjugate vaccine: Erythema | 220 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Infanrix hexa: Tenderness | 220 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Infanrix hexa: Erythema | 254 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Infanrix hexa: Swelling | 188 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | MenACYW conjugate vaccine: Swelling | 139 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | MenACYW conjugate vaccine: Tenderness | 161 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Prevnar 13: Tenderness | 196 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | MenACYW conjugate vaccine: Swelling | 111 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Infanrix hexa: Swelling | 189 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Prevnar 13: Erythema | 202 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Bexsero: Swelling | 192 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Infanrix hexa: Erythema | 231 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Prevnar 13: Swelling | 137 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Bexsero: Tenderness | 230 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | MenACYW conjugate vaccine: Erythema | 205 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Infanrix hexa: Tenderness | 216 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Bexsero: Erythema | 246 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Prevnar 13: Swelling | 69 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Infanrix hexa: Tenderness | 119 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Bexsero: Erythema | 136 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Bexsero: Swelling | 118 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Infanrix hexa: Erythema | 117 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Infanrix hexa: Swelling | 86 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Prevnar 13: Tenderness | 118 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Prevnar 13: Erythema | 104 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Injection Site Reactions After Any Vaccination | Bexsero: Tenderness | 138 Participants |
Number of Participants With Solicited Systemic Reactions After Any Vaccination
A SR was an expected AR (sign or symptom) observed and reported under the conditions (nature and onset) prelisted (i.e., solicited) in the CRB and considered as related to the product administered. Solicited systemic reactions included fever, vomiting, crying abnormal, drowsiness, appetite lost, and irritability. Reported AEs for each arm were presented as pre-specified in the study protocol.
Time frame: Within 7 days after any vaccination
Population: Analysis was performed on safety analysis set. Here, 'number analyzed' = participants with available data for each specified category.
| Arm | Measure | Group | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Appetite lost | 230 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Crying abnormal | 293 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Irritability | 306 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Fever | 100 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Drowsiness | 275 Participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Vomiting | 173 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Drowsiness | 275 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Appetite lost | 230 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Vomiting | 172 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Irritability | 299 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Crying abnormal | 273 Participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Fever | 86 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Irritability | 147 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Fever | 50 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Vomiting | 71 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Crying abnormal | 141 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Drowsiness | 137 Participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Number of Participants With Solicited Systemic Reactions After Any Vaccination | Appetite lost | 121 Participants |
Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Fold-rise was calculated as ratio of post-vaccination titer (i.e., 30 days post-vaccination at the age of 3 months) to pre-dose titer at the age of 3 months. Infancy was defined as up to 4 months of age.
Time frame: Before vaccination at the age of 3 months, 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months)
Population: Analysis was performed on PPAS1. Here, 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 5.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 45.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 70.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 29.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 82.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 25.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 18.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 53.8 percentage of participants |
Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Fold-rise was calculated as ratio of post-vaccination titer (i.e., 30 days post-vaccination at the age of 12 to 13 months) to pre-dose titer before vaccination at the age of 12 to 13 months.
Time frame: Before vaccination at the age of 12 to 13 months, 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 89.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 85.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 53.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 96.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Fold-rise was calculated as ratio of post-vaccination titer (i.e., 30 days post-vaccination at the age of 12 to 13 months) to pre-dose titer before vaccination at the age of 3 months.
Time frame: Before vaccination at the age of 3 months, 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 96.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 92.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 91.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in hSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 93.8 percentage of participants |
Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Fold-rise was calculated as ratio of post-vaccination titer (i.e., 30 days post-vaccination at the age of 3 months) to pre-dose titer at the age of 3 months. Infancy was defined as up to 4 months of age.
Time frame: Before vaccination at the age of 3 months, 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months)
Population: Analysis was performed on PPAS1. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 46.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 86.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 78.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 57.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 53.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 62.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 90.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 87.5 percentage of participants |
Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Fold-rise was calculated as ratio of post-vaccination titer (i.e., 30 days post-vaccination at the age of 12 to 13 months) to pre-dose titer before vaccination at the age of 12 to 13 months.
Time frame: Before vaccination at the age of 12 to 13 months, 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 83.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 71.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Fold-rise was calculated as ratio of post-vaccination titer (i.e., 30 days post-vaccination at the age of 12 to 13 months) to pre-dose titer before vaccination at the age of 3 months.
Time frame: Before vaccination at the age of 3 months, 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With >= 4-Fold Rise in rSBA Antibody Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with hSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months)
Population: Analysis was performed on PPAS1. Here, 'number analyzed' = participants with available data for each specified category and '0' in the number analyzed field denotes that no participant had available data for the specified titer category.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:64 | 7.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:64 | 66.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:8 | 73.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:512 | 1.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:128 | 54.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:64 | 2.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:256 | 1.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:256 | 32.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:128 | 1.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:512 | 20.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:4 | 87.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:1024 | 6.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:32 | 5.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: <1:4 | 18.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:256 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:128 | 4.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:4 | 81.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:64 | 7.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:8 | 66.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:32 | 21.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:16 | 40.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:16 | 51.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: <1:4 | 12.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: <1:4 | 6.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:16 | 21.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:4 | 93.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:32 | 21.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:8 | 35.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:8 | 87.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:4 | 56.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:16 | 85.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:128 | 1.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: <1:4 | 43.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:32 | 81.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: <1:4 | 14.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:4 | 85.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:8 | 66.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:16 | 42.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:32 | 19.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:64 | 9.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:128 | 2.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: <1:4 | 9.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:4 | 90.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:8 | 88.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:16 | 80.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:32 | 71.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:64 | 66.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:128 | 49.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:256 | 28.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:512 | 13.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:1024 | 5.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: <1:4 | 30.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:4 | 69.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:8 | 54.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:16 | 25.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:32 | 11.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:64 | 4.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:128 | 1.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: <1:4 | 53.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:4 | 46.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:8 | 27.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:16 | 13.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:32 | 4.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:64 | 1.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:16 | 6.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:32 | 16.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: <1:4 | 94.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:8 | 7.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: <1:4 | 21.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:4 | 5.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:4 | 21.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:8 | 2.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: <1:4 | 78.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:16 | 34.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:16 | 1.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:16 | 2.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:8 | 2.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:128 | 3.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:32 | 1.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:4 | 11.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:4 | 78.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:64 | 1.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: <1:4 | 89.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:64 | 9.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:64 | 1.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:8 | 51.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:32 | 3.6 percentage of participants |
Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Percentage of participants with hSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192; \>=1:16384; \>=1:32768; \>=1:65536 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'number analyzed' = participants with available data for each specified category and '0' in the number analyzed field denotes that no participant had available data for the specified titer category.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:16384 | 0.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:16 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:32 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:64 | 99.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:128 | 97.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:256 | 94.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:512 | 83.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:1024 | 68.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:2048 | 39.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4096 | 25.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:8192 | 10.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:16384 | 6.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:32768 | 0.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: <1:4 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:16 | 99.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:32 | 98.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:64 | 97.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:128 | 95.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:256 | 90.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:512 | 78.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:1024 | 64.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:2048 | 35.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4096 | 22.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:8192 | 8.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: <1:4 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:16 | 99.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:32 | 98.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:64 | 94.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:128 | 89.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:256 | 77.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:512 | 65.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 39.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 11.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 5.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:8192 | 1.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:16384 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: <1:4 | 0.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4 | 99.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:8 | 99.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:16 | 98.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:32 | 98.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:64 | 98.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:128 | 93.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:256 | 84.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:512 | 70.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:1024 | 45.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:2048 | 15.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4096 | 9.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:8192 | 2.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:16384 | 1.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: <1:4 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:32768 | 1.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:512 | 61.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:128 | 93.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:8192 | 3.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:8 | 99.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:8192 | 1.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4096 | 14.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:16 | 98.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:2048 | 13.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:32 | 94.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:512 | 73.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:16384 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:64 | 87.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:16384 | 1.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:16 | 99.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:128 | 75.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:64 | 98.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:256 | 85.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:256 | 58.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:32 | 98.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:512 | 35.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:8192 | 5.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:64 | 98.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:1024 | 17.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:64 | 95.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:16384 | 0.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:2048 | 1.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:32 | 98.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:128 | 89.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:1024 | 58.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:512 | 64.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: <1:4 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:256 | 81.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:32768 | 0.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:16384 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:16 | 99.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4096 | 4.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:256 | 86.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: <1:4 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: <1:4 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 32.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:2048 | 25.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:1024 | 43.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 9.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:16 | 99.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: <1:4 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:128 | 92.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:32 | 99.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 5.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:8 | 78.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:16 | 69.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:8 | 2.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:65536 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:32 | 56.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:64 | 30.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:128 | 22.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:16 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:256 | 7.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:512 | 4.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:1024 | 2.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:8192 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:8192 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:16384 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:32768 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:65536 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: <1:4 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: <1:4 | 46.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4 | 53.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:8 | 35.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:16 | 23.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:32 | 6.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:16384 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4 | 100 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:8 | 100 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:8192 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:16 | 100 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:32 | 97.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:64 | 93.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:16384 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:128 | 90.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:256 | 83.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:512 | 76.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:32768 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:1024 | 52.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:65536 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:2048 | 26.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:32768 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:65536 | 1.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4096 | 15.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:8192 | 5.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: <1:4 | 96.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:16384 | 2.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:32768 | 1.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: <1:4 | 10.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4 | 3.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4 | 89.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4096 | 0 percentage of participants |
Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Percentage of participants with hSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: Before vaccination at the age of 3 months
Population: Analysis was performed on PPAS1. Here, 'number analyzed' = participants with available data for each specified category and '0' in the number analyzed field denotes that no participant had available data for the specified titer category.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:32 | 4.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:256 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:32 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:32 | 22.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:128 | 3.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:64 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:64 | 3.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:128 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:16 | 4.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:32 | 3.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:256 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:64 | 4.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:4 | 81.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:8 | 8.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: <1:4 | 70.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:128 | 4.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:16 | 7.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:4 | 29.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:8 | 22.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:4 | 16.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:256 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:8 | 59.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: <1:4 | 18.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: <1:4 | 44.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:64 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: <1:4 | 83.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:4 | 55.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:16 | 36.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:8 | 25.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:16 | 7.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: <1:4 | 25.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:4 | 74.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:8 | 48.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:16 | 33.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:32 | 11.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:64 | 7.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:128 | 7.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:256 | 3.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: <1:4 | 61.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:4 | 38.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:8 | 20.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:16 | 11.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:32 | 5.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:64 | 5.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:128 | 5.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:256 | 2.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:512 | 2.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: <1:4 | 73.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:4 | 26.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:8 | 10.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:16 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:32 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:64 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: <1:4 | 89.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:8 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:16 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:32 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:64 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:4 | 10.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:8 | 14.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:8 | 48.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:4 | 37.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: <1:4 | 24.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: <1:4 | 62.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: <1:4 | 87.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:128 | 3.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:64 | 10.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:4 | 75.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:8 | 3.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:4 | 15.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:32 | 20.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:8 | 12.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: <1:4 | 84.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:4 | 12.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:16 | 3.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:16 | 3.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:64 | 2.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:16 | 27.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:32 | 2.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:16 | 11.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:32 | 3.1 percentage of participants |
Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with hSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192; \>=1:16384; \>=1:32768; \>=1:65536 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: Before vaccination at the age of 12 to 13 months
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Here, '0' in the number analyzed field denotes that no participant had available data for the specified titer category.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:256 | 6.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:16384 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:16384 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: <1:4 | 2.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:8 | 93.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4 | 97.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:8 | 88.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: <1:4 | 5.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:16 | 77.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:32 | 60.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:16 | 90.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:64 | 45.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4 | 94.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:128 | 28.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:256 | 8.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:512 | 5.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:8 | 85.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:16 | 71.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:16384 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:32 | 64.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:32 | 65.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:64 | 48.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:64 | 48.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:128 | 20.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:256 | 5.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:128 | 29.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:256 | 22.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:512 | 3.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:16384 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: <1:4 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: <1:4 | 3.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4 | 96.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:8 | 93.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:2048 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:16 | 78.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:32 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:64 | 28.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:128 | 12.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:16 | 42.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:16384 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:32 | 34.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4 | 96.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:16 | 34.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:64 | 3.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:64 | 23.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:16384 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:2048 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:128 | 15.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: <1:4 | 15.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:32 | 19.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4 | 84.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:8 | 76.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: <1:4 | 11.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:8 | 69.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:16 | 46.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: <1:4 | 26.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:32 | 61.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:32 | 23.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4 | 88.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:64 | 11.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: <1:4 | 3.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:128 | 3.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4 | 73.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:256 | 3.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:16 | 73.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:128 | 3.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:8 | 53.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:16384 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:8 | 73.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:64 | 11.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:16384 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:65536 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:32 | 41.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:16384 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: <1:4 | 11.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4 | 88.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:16 | 55.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:64 | 29.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:128 | 23.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:256 | 5.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:512 | 2.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:8192 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:16384 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:32768 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:65536 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: <1:4 | 94.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4 | 5.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:8 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:16 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:8192 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:16384 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:32768 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:65536 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: <1:4 | 94.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4 | 5.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:8 | 5.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:16 | 2.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:32 | 2.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:64 | 2.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:128 | 2.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:256 | 2.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:8192 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:16384 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:32768 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:65536 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: <1:4 | 100 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:8 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:16 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:8192 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:32768 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of hSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:8 | 73.5 percentage of participants |
Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with rSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months)
Population: Analysis was performed on PPAS1. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Here, '0' in the number analyzed field denotes that no participant had available data for the specified titer category.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:32 | 89.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:128 | 75.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:1024 | 5.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:64 | 81.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:64 | 36.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:512 | 36.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:128 | 78.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:2048 | 5.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:256 | 63.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:256 | 71.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:64 | 75.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:128 | 80.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:512 | 55.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:128 | 19.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:64 | 80.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:1024 | 23.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:4 | 61.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:32 | 83.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:2048 | 5.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:32 | 75.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:16 | 88.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:4096 | 2.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:256 | 8.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: <1:4 | 8.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:16 | 77.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:8 | 91.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:4 | 91.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:512 | 5.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:1024 | 11.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:8 | 77.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:1024 | 5.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:8 | 52.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:4 | 77.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:2048 | 2.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: <1:4 | 22.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:512 | 19.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:16 | 44.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: <1:4 | 2.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: <1:4 | 38.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:256 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:8 | 97.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:32 | 41.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:16 | 94.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:4 | 97.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:2048 | 2.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:4 | 92.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: <1:4 | 21.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:4 | 78.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:8 | 65.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:16 | 53.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:32 | 43.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:64 | 31.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:128 | 28.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:256 | 21.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:512 | 9.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:1024 | 3.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:2048 | 3.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: <1:4 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:16 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:32 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:64 | 96.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:128 | 96.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:256 | 65.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:512 | 40.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:1024 | 28.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:2048 | 9.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:4096 | 3.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:8192 | 3.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: <1:4 | 8.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:8 | 92.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:16 | 88.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:32 | 80.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:64 | 72.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:128 | 68.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:256 | 48.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:512 | 36.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:1024 | 12.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:2048 | 4.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:4096 | 4.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: <1:4 | 33.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:4 | 66.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:8 | 63.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:16 | 63.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:32 | 63.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:64 | 63.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:128 | 53.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:256 | 50.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:512 | 26.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:1024 | 13.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:2048 | 3.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:1024 | 3.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:16 | 5.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:2048 | 3.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:8 | 8.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:16 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:4 | 13.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: <1:4 | 97.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: <1:4 | 100 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:8 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:4 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:8 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:16 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:4 | 9.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: <1:4 | 90.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:8 | 9.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:4 | 2.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:16 | 9.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:32 | 6.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:64 | 3.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: <1:4 | 86.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:128 | 3.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup W: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:256 | 3.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup A: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup Y: >=1:512 | 3.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS1 | Serogroup C: >=1:32 | 5.4 percentage of participants |
Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Percentage of participants with rSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192; \>=1:16384; \>=1:32768 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Here, '0' in the number analyzed field denotes that no participant had available data for the specified titer category.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:64 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:512 | 97.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:8192 | 17.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:128 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:128 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 44.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:256 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 77.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:512 | 89.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:256 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 93.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:256 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:512 | 97.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:2048 | 51.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:256 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4096 | 21.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:128 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:128 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:8192 | 8.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:512 | 97.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:16384 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:8192 | 28.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:64 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: <1:4 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:1024 | 87.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:64 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:32 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:32 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:16 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:2048 | 53.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:16 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4096 | 29.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4096 | 39.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:8192 | 6.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:16 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:16384 | 2.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: <1:4 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:2048 | 73.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: <1:4 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:32 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:1024 | 74.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: <1:4 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:1024 | 87.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:16 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:64 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:32768 | 2.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:32 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:16384 | 2.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:16384 | 2.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: <1:4 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:16 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:32 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:64 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:128 | 97.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:256 | 97.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:512 | 88.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:1024 | 79.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:2048 | 51.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4096 | 32.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:8192 | 9.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:16384 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: <1:4 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:16 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:32 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:64 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:128 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:256 | 95.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:512 | 88.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:1024 | 72.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:2048 | 53.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4096 | 34.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:8192 | 9.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:16384 | 4.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: <1:4 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:16 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:32 | 97.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:64 | 97.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:128 | 97.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:256 | 95.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:512 | 95.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 79.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 53.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 20.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:8192 | 9.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:16384 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: <1:4 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:16 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:32 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:64 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:128 | 97.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:256 | 97.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:512 | 95.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:1024 | 86.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:2048 | 74.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4096 | 46.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:8192 | 25.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:16384 | 9.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 11.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:64 | 11.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:64 | 85.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:32 | 11.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4 | 85.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:16 | 11.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:512 | 2.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4 | 11.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:32 | 85.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: <1:4 | 81.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: <1:4 | 88.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4 | 19.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:4096 | 17.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:16 | 85.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:8 | 16.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:2048 | 36.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: <1:4 | 14.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:16 | 16.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:1024 | 51.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:32 | 16.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:8 | 93.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:512 | 68.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:16 | 93.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:4 | 93.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:8 | 85.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:32 | 93.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: <1:4 | 7.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:64 | 16.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:64 | 93.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:256 | 75.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:128 | 93.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:8 | 11.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:256 | 90.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:128 | 11.9 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:512 | 79.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup A: >=1:128 | 85.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 67.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 46.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup C: >=1:128 | 9.1 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W After Vaccination - PPAS3 | Serogroup W: >=1:256 | 4.8 percentage of participants |
Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with rSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: Before vaccination at the age of 3 months
Population: Analysis was performed on PPAS1. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Here, '0' in the number analyzed field denotes that no participant had available data for the specified titer category.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:2048 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:64 | 5.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:128 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:128 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:256 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:256 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:128 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:256 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:64 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:8 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:32 | 10.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:32 | 11.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: <1:4 | 89.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:64 | 5.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:16 | 10.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:4 | 10.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:16 | 11.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:8 | 10.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:2048 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:16 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:8 | 11.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: <1:4 | 84.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:32 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:4 | 11.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:4 | 15.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:4 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: <1:4 | 88.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:8 | 15.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:16 | 10.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:64 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:32 | 5.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: <1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: <1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:4 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:8 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:16 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:32 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:64 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:2048 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: <1:4 | 82.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:4 | 17.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:8 | 17.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:16 | 17.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:32 | 17.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:64 | 13.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:128 | 4.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:256 | 4.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: <1:4 | 87.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:4 | 13.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:8 | 13.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:16 | 8.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:32 | 4.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:64 | 4.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:2048 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: <1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:4 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:8 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:16 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:32 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:64 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:16 | 7.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:8 | 11.5 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:4 | 15.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:4 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: <1:4 | 96.2 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: <1:4 | 84.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:4 | 3.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:16 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:8 | 3.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:16 | 3.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:4 | 15.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:8 | 15.4 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: <1:4 | 84.6 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:32 | 3.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:16 | 7.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:8 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:32 | 3.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:64 | 3.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:64 | 3.8 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: <1:4 | 100 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup C: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS1 | Serogroup A: >=1:64 | 0 percentage of participants |
Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with rSBA antibody titers distribution \<1:4, \>=1:4, \>=1:8, \>=1:16; \>=1:32; \>=1:64, \>=1:128, \>=1:256; \>=1:512; \>=1:1024; \>=1:2048; \>=1:4096; \>=1:8192; \>=1:16384; \>=1:32768 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: Before vaccination at the age of 12 to 13 months
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Here, '0' in the number analyzed field denotes that no participant had available data for the specified titer category.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:64 | 71.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:16384 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:128 | 42.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:256 | 14.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:256 | 33.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 14.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:8 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 14.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 14.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:512 | 33.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:512 | 14.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:128 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:256 | 14.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:128 | 20.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:16384 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:1024 | 33.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: <1:4 | 14.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:2048 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:128 | 28.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4 | 85.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:16 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:64 | 57.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:8 | 85.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:64 | 20.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:32 | 71.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:16 | 85.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:32 | 20.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:8192 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4096 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:16384 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:32 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:32768 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: <1:4 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:16 | 40.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:64 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:8 | 40.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: <1:4 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4 | 60.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:16 | 85.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: <1:4 | 40.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:32 | 71.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:16384 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:8 | 60.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: <1:4 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4 | 80.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:8 | 80.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:16 | 80.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:32 | 80.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:64 | 80.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:128 | 80.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:256 | 60.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:512 | 40.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:1024 | 40.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:2048 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:16384 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: <1:4 | 80.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:8 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:16 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:32 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:64 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:16384 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: <1:4 | 40.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4 | 60.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:8 | 40.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:16 | 40.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:32 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:64 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:16384 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:32768 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: <1:4 | 40.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4 | 60.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:16 | 40.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:32 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:64 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4096 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:8192 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:16384 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:64 | 50.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: <1:4 | 50.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:16 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: <1:4 | 100 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:8 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:32 | 50.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:8 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: <1:4 | 100 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4 | 50.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:16 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:4096 | 16.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:2048 | 16.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:16 | 50.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:512 | 33.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:16 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:8 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:1024 | 16.7 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:32 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:4 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:64 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: <1:4 | 100 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:256 | 33.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:128 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:4096 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup W: >=1:256 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:128 | 33.3 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:1024 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:512 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup A: >=1:8 | 50.0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup Y: >=1:2048 | 0 percentage of participants |
| Group 3: Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Distribution of rSBA Titers Against Meningococcal Serogroups A, C, Y, and W Before Vaccination - PPAS3 | Serogroup C: >=1:256 | 0 percentage of participants |
Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.4 and \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months)
Population: Analysis was performed on PPAS1. Here, 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:4 | 87.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:8 | 73.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:4 | 93.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:8 | 87.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:4 | 81.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:8 | 66.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:4 | 56.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:8 | 35.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:8 | 27.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:4 | 85.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:4 | 69.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:8 | 66.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:4 | 46.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:4 | 90.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:8 | 54.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:8 | 88.3 percentage of participants |
Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Percentage of participants with antibody titers \>=1.4 and \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:4 | 99.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:8 | 99.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:8 | 99.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:4 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:8 | 100 percentage of participants |
Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.4 and \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: Before vaccination at the age of 3 months
Population: Analysis was performed on PPAS1. Here, 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:4 | 81.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:8 | 59.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:4 | 55.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:8 | 25.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:4 | 29.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:8 | 22.2 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:4 | 16.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:8 | 8.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:8 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:4 | 74.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:4 | 26.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:8 | 48.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:4 | 10.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:4 | 38.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:8 | 10.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:8 | 20.6 percentage of participants |
Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.4 and \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: Before vaccination at the age of 12 to 13 months
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:4 | 97.1 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:4 | 94.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:8 | 85.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:8 | 88.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:4 | 96.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:8 | 93.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:8 | 93.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:8 | 76.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:4 | 84.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:8 | 69.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:4 | 96.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:8 | 73.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:4 | 73.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:8 | 53.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:4 | 88.5 percentage of participants |
Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by hSBA assay. Percentage of participants with hSBA antibody titers \>=1.4 and \>=1:8 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) and before vaccination at the age of 12-13 months
Population: Analysis was performed on PPAS2. Here, 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: 30 days after 3-month vaccination: >= 1:4 | 75.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: 30 days after 3-month vaccination: >= 1:4 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: 30 days after 3-month vaccination: >= 1:8 | 65.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: Before 12-13 months vaccination: >= 1:8 | 91.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: Before 12-13 months vaccination: >= 1:4 | 94.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: 30 days after 3-month vaccination: >= 1:8 | 92.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: Before 12-13 months vaccination: >= 1:8 | 89.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: 30 days after 3-month vaccination: >= 1:8 | 81.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: 30 days after 3-month vaccination: >= 1:4 | 51.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: Before 12-13 months vaccination: >= 1:4 | 87.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: 30 days after 3-month vaccination: >= 1:8 | 37.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: 30 days after 3-month vaccination: >= 1:4 | 88.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: Before 12-13 months vaccination: >= 1:4 | 92.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: Before 12-13 months vaccination: >= 1:8 | 80.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: Before 12-13 months vaccination: >= 1:8 | 85.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: Before 12-13 months vaccination: >= 1:4 | 97.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: Before 12-13 months vaccination: >= 1:8 | 68.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: Before 12-13 months vaccination: >= 1:8 | 83.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: 30 days after 3-month vaccination: >= 1:4 | 89.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: 30 days after 3-month vaccination: >= 1:8 | 64.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: 30 days after 3-month vaccination: >= 1:4 | 96.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: 30 days after 3-month vaccination: >= 1:8 | 92.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: Before 12-13 months vaccination: >= 1:4 | 80.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: Before 12-13 months vaccination: >= 1:8 | 69.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: 30 days after 3-month vaccination: >= 1:4 | 57.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: 30 days after 3-month vaccination: >= 1:8 | 46.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: Before 12-13 months vaccination: >= 1:4 | 90.9 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: Before 12-13 months vaccination: >= 1:8 | 78.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: 30 days after 3-month vaccination: >= 1:4 | 39.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: 30 days after 3-month vaccination: >= 1:8 | 28.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: Before 12-13 months vaccination: >= 1:4 | 88.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With hSBA Antibody Titers >=1:4 and >=1:8 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: Before 12-13 months vaccination: >= 1:4 | 97.2 percentage of participants |
Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.8 and \>=1:128 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months)
Population: Analysis was performed on PPAS1. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:8 | 52.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:128 | 19.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:8 | 97.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:128 | 78.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:8 | 91.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:128 | 80.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:8 | 77.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:128 | 75.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:128 | 53.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:8 | 65.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:8 | 92.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:128 | 28.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:8 | 63.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:128 | 68.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:128 | 96.9 percentage of participants |
Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Percentage of participants with antibody titers \>=1.8 and \>=1:128 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:128 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:128 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:128 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:128 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:128 | 97.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:128 | 97.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:128 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:128 | 97.7 percentage of participants |
Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.8 and \>=1:128 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: Before vaccination at the age of 3 months
Population: Analysis was performed on PPAS1. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:8 | 10.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:8 | 15.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:128 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:8 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:8 | 11.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:128 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:128 | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:8 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:8 | 17.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup C: >= 1:128 | 4.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:8 | 13.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y: >= 1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup W: >= 1:8 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS1 | Serogroup A: >= 1:128 | 0 percentage of participants |
Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Infancy was defined as up to 4 months of age. Percentage of participants with antibody titers \>=1.8 and \>=1:128 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: Before vaccination at the age of 12 to 13 months
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:8 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:128 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:128 | 42.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:8 | 85.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:128 | 28.6 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:8 | 40.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:128 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:8 | 80.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:8 | 40.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup A: >= 1:128 | 80.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup W: >= 1:8 | 60.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:8 | 20.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y: >= 1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W Before Vaccination: Group 1 and 2 - PPAS3 | Serogroup C: >= 1:128 | 0 percentage of participants |
Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2
Antibody titers of Meningococcal Serogroups A, C, Y, and W were measured by rSBA assay. Percentage of participants with rSBA antibody titers \>=1:8 and \>=1:128 for meningococcal serogroups A, C, Y, and W were reported in this outcome measure.
Time frame: 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months) and before vaccination at the age of 12-13 months
Population: Analysis was performed on PPAS2. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: 30 days after 3-month vaccination: >= 1:8 | 66.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: 30 days after 3-month vaccination: >= 1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: 30 days after 3-month vaccination: >= 1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: 30 days after 3-month vaccination: >= 1:128 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: Before 12-13 months vaccination: >= 1:8 | 42.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: Before 12-13 months vaccination: >= 1:8 | 87.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: 30 days after 3-month vaccination: >= 1:128 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: Before 12-13 months vaccination: >= 1:128 | 37.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: 30 days after 3-month vaccination: >= 1:128 | 66.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: 30 days after 3-month vaccination: >= 1:8 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: Before 12-13 months vaccination: >= 1:8 | 87.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: 30 days after 3-month vaccination: >= 1:128 | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: Before 12-13 months vaccination: >= 1:128 | 42.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: Before 12-13 months vaccination: >= 1:8 | 50.0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: Before 12-13 months vaccination: >= 1:128 | 37.5 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: Before 12-13 months vaccination: >= 1:128 | 33.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: Before 12-13 months vaccination: >= 1:128 | 11.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: 30 days after 3-month vaccination: >= 1:8 | 66.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: 30 days after 3-month vaccination: >= 1:128 | 16.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: Before 12-13 months vaccination: >= 1:8 | 55.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup A: Before 12-13 months vaccination: >= 1:128 | 44.4 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: 30 days after 3-month vaccination: >= 1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: 30 days after 3-month vaccination: >= 1:128 | 83.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup C: Before 12-13 months vaccination: >= 1:8 | 55.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: Before 12-13 months vaccination: >= 1:128 | 0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: 30 days after 3-month vaccination: >= 1:8 | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: 30 days after 3-month vaccination: >= 1:128 | 50.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: Before 12-13 months vaccination: >= 1:8 | 62.5 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup Y: Before 12-13 months vaccination: >= 1:128 | 25.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: 30 days after 3-month vaccination: >= 1:8 | 66.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: 30 days after 3-month vaccination: >= 1:128 | 66.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With rSBA Antibody Titers >=1:8 and >=1:128 Against Meningococcal Serogroups A, C, Y, and W - PPAS2 | Serogroup W: Before 12-13 months vaccination: >= 1:8 | 33.3 percentage of participants |
Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1
The hSBA vaccine seroresponse against serogroups A, C, Y, and W was defined as post-vaccination hSBA titer \>=1:16 for participants with pre-vaccination hSBA titer \<1:8 or at least a 4-fold increase in hSBA titers from pre to post-vaccination for participants with pre-vaccination hSBA titers \>=1:8. Infancy was defined as up to 4 months of age.
Time frame: Before vaccination at the age of 3 months up to 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months)
Population: Analysis was performed on PPAS1. Here, 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 0 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 66.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 33.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 25.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 11.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 20.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 30.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 79.4 percentage of participants |
Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
The hSBA vaccine seroresponse against serogroups A, C, Y, and W was defined as post-vaccination hSBA titer \>=1:16 for participants with pre-vaccination hSBA titer \<1:8 or at least a 4-fold increase in hSBA titers from pre to post-vaccination for participants with pre-vaccination hSBA titers \>=1:8.
Time frame: Before vaccination at the age of 3 months up to 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 92.9 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 96.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 91.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 96.6 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 93.8 percentage of participants |
Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
The hSBA vaccine seroresponse against serogroups A, C, Y, and W was defined as post-vaccination hSBA titer \>=1:16 for participants with pre-vaccination hSBA titer \<1:8 or at least a 4-fold increase in hSBA titers from pre to post-vaccination for participants with pre-vaccination hSBA titers \>=1:8.
Time frame: Before vaccination at the age of 12 to 13 months up to 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 89.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 85.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 53.8 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 96.2 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by hSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 96.0 percentage of participants |
Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1
The rSBA vaccine seroresponse against serogroups A, C, Y, and W was defined as post-vaccination rSBA titer \>=1:32 for participants with pre-vaccination rSBA titer \<1:8 or at least a 4-fold increase in hSBA titers from pre to post-vaccination for participants with pre-vaccination hSBA titers \>=1:8. Infancy was defined as up to 4 months of age.
Time frame: Before vaccination at the age of 3 months up to 30 days post-vaccination at the age of 3 months (i.e., at the age of 4 months)
Population: Analysis was performed on PPAS1. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 30.8 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 86.7 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 71.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 57.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup W | 53.3 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup A | 50.0 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup Y | 72.7 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS1 | Serogroup C | 87.5 percentage of participants |
Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
The rSBA vaccine seroresponse against serogroups A, C, Y, and W was defined as post-vaccination rSBA titer \>=1:32 for participants with pre-vaccination rSBA titer \<1:8 or at least a 4-fold increase in hSBA titers from pre to post-vaccination for participants with pre-vaccination hSBA titers \>=1:8.
Time frame: Before vaccination at the age of 12 to 13 months up to 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 83.3 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 71.4 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3
The rSBA vaccine seroresponse against serogroups A, C, Y, and W was defined as post-vaccination rSBA titer \>=1:32 for participants with pre-vaccination rSBA titer \<1:8 or at least a 4-fold increase in hSBA titers from pre to post-vaccination for participants with pre-vaccination hSBA titers \>=1:8.
Time frame: Before vaccination at the age of 3 months up to 30 days post-vaccination at the age of 12 to 13 months (i.e., at the age of 13 to 14 months)
Population: Analysis was performed on PPAS3. Here, 'overall number of participants analyzed' = participants with available data for this outcome measure and 'number analyzed' = participants with available data for each specified category. Data for this outcome measure was not planned to be collected and analyzed for Group 3.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 100 percentage of participants |
| Group 1: MenACYW Conjugate Vaccine + Bexsero® (2, 4, and 12 to 13 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup W | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup A | 100 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup Y | 94.1 percentage of participants |
| Group 2: MenACYW Conjugate Vaccine + Bexsero® (2 and 4 Months) | Percentage of Participants With Vaccine Seroresponse Measured by rSBA Against Meningococcal Serogroups A, C, Y, and W After Vaccination: Group 1 and 2 - PPAS3 | Serogroup C | 100 percentage of participants |