Meningococcal Group B Vaccine

BIOLOGICAL7 trials

Conditions

Gonococcal InfectionGonorrhea MaleGonorrhoeaHealthy VolunteersHealthy Volunteers (Meningococcal Infection)Meningococcal ImmunisationMeningococcal ImmunizationNeisseria Gonorrhoeae Infection

Phase 1

Study of an Investigational Pentavalent Meningococcal ABCYW Vaccine in Adults and Adolescents

CompletedNCT06128733

Sanofi Pasteur, a Sanofi CompanyHealthy Volunteers, Meningococcal Immunisation

Start: 2023-10-31End: 2025-08-27Updated: 2026-01-13

Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants

Active, not recruitingNCT06647407

Sanofi Pasteur, a Sanofi CompanyHealthy Volunteers, Meningococcal Immunization

Start: 2024-11-05End: 2027-05-17Target: 750Updated: 2026-01-20

Phase 2

Safety and Efficacy Study of Meningococcal Group B Vaccine rMenB+OMV NZ (Bexsero) to Prevent Gonococcal Infection

Active, not recruitingNCT04350138

National Institute of Allergy and Infectious Diseases (NIAID)Gonococcal Infection

Start: 2020-12-29End: 2026-10-01Updated: 2026-03-20

Mucosal Immunity Against Neisseria Gonorrhoeae After 4CMenB Vaccination

CompletedNCT04722003

National Institute of Allergy and Infectious Diseases (NIAID)Gonorrhoea

Start: 2021-11-01End: 2023-10-02Updated: 2024-11-05

Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae

CompletedNCT05294588

University of North Carolina, Chapel HillGonorrhea Male

Start: 2022-04-18End: 2026-02-05Updated: 2026-03-02

Phase 3

Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine in Infants and Toddlers When Administered Concomitantly With Routine Pediatric Vaccines in the United Kingdom

CompletedNCT03632720

Sanofi Pasteur, a Sanofi CompanyHealthy Volunteers (Meningococcal Infection)

Start: 2018-10-10End: 2022-12-05Updated: 2023-11-07

Phase 4

Study to Assess Gonorrhoeae Immune Responses Induced by a N. Meningitidis Vaccine

CompletedNCT04094883

University of North Carolina, Chapel HillNeisseria Gonorrhoeae Infection

Start: 2019-10-09End: 2020-09-01Updated: 2021-07-15

Related Papers

Efficacy of the Serogroup B Neisseria meningitidis Vaccine (4CMenB) in Preventing Experimental Neisseria gonorrhoeae Urethral Infection: A Double-Blind Randomized Controlled Human Challenge Study Protocol

2025-12-15

Multicentre double-blind randomised placebo-controlled trial evaluating the efficacy of the meningococcal B vaccine, 4CMenB (Bexsero), againstNeisseria gonorrhoeaeinfection in men who have sex with men: the GoGoVax study protocol

BMJ Open2024-04-018 citations

An Observational Study to Assess the Effectiveness of 4CMenB against Meningococcal Disease and Carriage and Gonorrhea in Adolescents in the Northern Territory, Australia—Study Protocol

Vaccines2022-02-1613 citations